Gene Symbol: SIGE
Description: sigma factor E
Alias: ATSIG5, MLE8.4, MLE8_4, SIG5, SIGMA FACTOR, SIGMA FACTOR 5, sigma factor E, sigma factor E
Species: thale cress

Top Publications

  1. Zhao P, Cui R, Xu P, Wu J, Mao J, Chen Y, et al. ATHB17 enhances stress tolerance by coordinating photosynthesis associated nuclear gene and ATSIG5 expression in response to abiotic stress. Sci Rep. 2017;7:45492 pubmed publisher
    ..Moreover, we identified ATSIG5, encoding a plastid sigma factor, as one of the target genes of ATHB17...
  2. Yao J, Roy Chowdhury S, Allison L. AtSig5 is an essential nucleus-encoded Arabidopsis sigma-like factor. Plant Physiol. 2003;132:739-47 pubmed
    ..One of these genes, Arabidopsis SIG5, encodes a sigma-factor, AtSig5, which is phylogenetically distinct from the other family members...
  3. Schweer J, Loschelder H, Link G. A promoter switch that can rescue a plant sigma factor mutant. FEBS Lett. 2006;580:6617-22 pubmed
    ..The NEP promoter cluster can help maintain RNA synthesis in situations where no functional sigma factor is available for PEP.
  4. Fujiwara M, Nagashima A, Kanamaru K, Tanaka K, Takahashi H. Three new nuclear genes, sigD, sigE and sigF, encoding putative plastid RNA polymerase sigma factors in Aarabidopsis thaliana. FEBS Lett. 2000;481:47-52 pubmed
    Three new nuclear genes (sigD, sigE and sigF) of Arabidopsis thaliana, encoding putative plastid RNA polymerase sigma factors, were identified and analyzed...
  5. Brown B, Jenkins G. UV-B signaling pathways with different fluence-rate response profiles are distinguished in mature Arabidopsis leaf tissue by requirement for UVR8, HY5, and HYH. Plant Physiol. 2008;146:576-88 pubmed
    ..This research provides evidence that, in UV-B signaling, UVR8, HY5, and HYH act together in a photoregulatory pathway and demonstrates a new role for HYH in UV-B responses. ..
  6. Tsunoyama Y, Ishizaki Y, Morikawa K, Kobori M, Nakahira Y, Takeba G, et al. Blue light-induced transcription of plastid-encoded psbD gene is mediated by a nuclear-encoded transcription initiation factor, AtSig5. Proc Natl Acad Sci U S A. 2004;101:3304-9 pubmed publisher
    ..The replacement of the plastid sigma factor associated with PEP may be the major mechanism for switching of plastid transcription pattern in response to ..
  7. Belbin F, Noordally Z, Wetherill S, Atkins K, Franklin K, Dodd A. Integration of light and circadian signals that regulate chloroplast transcription by a nuclear-encoded sigma factor. New Phytol. 2017;213:727-738 pubmed publisher
    ..Transcripts encoding the sigma factor SIG5 are regulated by light and the circadian clock...
  8. Yu F, Shi J, Zhou J, Gu J, Chen Q, Li J, et al. ANK6, a mitochondrial ankyrin repeat protein, is required for male-female gamete recognition in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2010;107:22332-7 pubmed publisher
    ..ANK6 was localized to the mitochondria, where it interacted with SIG5, a transcription initiation factor previously found to be essential for fertility...
  9. Noordally Z, Ishii K, Atkins K, Wetherill S, Kusakina J, Walton E, et al. Circadian control of chloroplast transcription by a nuclear-encoded timing signal. Science. 2013;339:1316-9 pubmed publisher
    ..We show that, in Arabidopsis, nuclear-encoded SIGMA FACTOR5 (SIG5) controls circadian rhythms of transcription of several chloroplast genes, revealing one pathway by which the ..

More Information


  1. Tsunoyama Y, Morikawa K, Shiina T, Toyoshima Y. Blue light specific and differential expression of a plastid sigma factor, Sig5 in Arabidopsis thaliana. FEBS Lett. 2002;516:225-8 pubmed
    ..levels of six different SIG genes in Arabidopsis and found that blue light extensively induced the accumulation of SIG5 transcripts, but red light did not...
  2. Onda Y, Yagi Y, Saito Y, Takenaka N, Toyoshima Y. Light induction of Arabidopsis SIG1 and SIG5 transcripts in mature leaves: differential roles of cryptochrome 1 and cryptochrome 2 and dual function of SIG5 in the recognition of plastid promoters. Plant J. 2008;55:968-78 pubmed publisher
    ..We analysed the light induction profiles of transcripts from six Arabidopsis sigma factor (AtSIG) genes in mature leaves, focusing on the effects of wavelength and intensity...
  3. Yamburenko M, Zubo Y, Börner T. Abscisic acid affects transcription of chloroplast genes via protein phosphatase 2C-dependent activation of nuclear genes: repression by guanosine-3'-5'-bisdiphosphate and activation by sigma factor 5. Plant J. 2015;82:1030-41 pubmed publisher
    ..On the other hand, sigma factor 5 (SIG5) and plastid transcription factor 1 (PTF1) are known to be necessary for the transcription of psbD from ..
  4. Tepperman J, Hwang Y, Quail P. phyA dominates in transduction of red-light signals to rapidly responding genes at the initiation of Arabidopsis seedling de-etiolation. Plant J. 2006;48:728-42 pubmed
  5. Ruckle M, Burgoon L, Lawrence L, Sinkler C, Larkin R. Plastids are major regulators of light signaling in Arabidopsis. Plant Physiol. 2012;159:366-90 pubmed publisher
    ..We conclude that the integration of light and plastid signaling regulates a number of END genes that help optimize chloroplast function and that at least some END genes affect photosynthesis-related gene expression...