Gene Symbol: SEUSS
Description: SEUSS transcriptional co-regulator
Alias: F28H19.10, F28H19_10, seuss, SEUSS transcriptional co-regulator
Species: thale cress
Products:     SEUSS

Top Publications

  1. Sridhar V, Surendrarao A, Gonzalez D, Conlan R, Liu Z. Transcriptional repression of target genes by LEUNIG and SEUSS, two interacting regulatory proteins for Arabidopsis flower development. Proc Natl Acad Sci U S A. 2004;101:11494-9 pubmed
    ..LEUNIG (LUG) and SEUSS (SEU) normally act to prevent ectopic expression of the floral homeotic gene AGAMOUS in flowers...
  2. Bao F, Azhakanandam S, Franks R. SEUSS and SEUSS-LIKE transcriptional adaptors regulate floral and embryonic development in Arabidopsis. Plant Physiol. 2010;152:821-36 pubmed publisher
    ..The Arabidopsis (Arabidopsis thaliana) SEUSS (SEU) gene encodes a transcriptional adaptor that shares sequence similarity with metazoan Lim domain-binding ..
  3. Nole Wilson S, Rueschhoff E, Bhatti H, Franks R. Synergistic disruptions in seuss cyp85A2 double mutants reveal a role for brassinolide synthesis during gynoecium and ovule development. BMC Plant Biol. 2010;10:198 pubmed publisher
    The Arabidopsis SEUSS (SEU) gene encodes a transcriptional adaptor protein that is required for a diverse set of developmental events, including floral organ identity specification, as well as gynoecium, ovule and embryo development...
  4. Sridhar V, Surendrarao A, Liu Z. APETALA1 and SEPALLATA3 interact with SEUSS to mediate transcription repression during flower development. Development. 2006;133:3159-66 pubmed
    ..Previously, we identified and isolated two Arabidopsis transcription co-repressors LEUNIG (LUG) and SEUSS (SEU) that function together in a putative co-repressor complex to prevent ectopic AGAMOUS (AG) transcription in ..
  5. Franks R, Wang C, Levin J, Liu Z. SEUSS, a member of a novel family of plant regulatory proteins, represses floral homeotic gene expression with LEUNIG. Development. 2002;129:253-63 pubmed
    ..We report the genetic identification and characterization of a novel gene, SEUSS, that is required in the negative regulation of AGAMOUS...
  6. Gregis V, Sessa A, Colombo L, Kater M. AGL24, SHORT VEGETATIVE PHASE, and APETALA1 redundantly control AGAMOUS during early stages of flower development in Arabidopsis. Plant Cell. 2006;18:1373-82 pubmed
    ..The observed phenotypes remarkably resembled the leunig (lug) and seuss (seu) mutants...
  7. Sitaraman J, Bui M, Liu Z. LEUNIG_HOMOLOG and LEUNIG perform partially redundant functions during Arabidopsis embryo and floral development. Plant Physiol. 2008;147:672-81 pubmed publisher
    ..LUG was previously shown to form a putative corepressor complex with another protein, SEUSS (SEU), and to repress the transcription of AGAMOUS in floral organ identity specification...
  8. Pfluger J, Zambryski P. The role of SEUSS in auxin response and floral organ patterning. Development. 2004;131:4697-707 pubmed
    ..The modifier was discovered to be a new allele of the seuss (seu) mutant...
  9. Azhakanandam S, Nole Wilson S, Bao F, Franks R. SEUSS and AINTEGUMENTA mediate patterning and ovule initiation during gynoecium medial domain development. Plant Physiol. 2008;146:1165-81 pubmed publisher
    ..Here we report a synergistic genetic interaction between seuss and aintegumenta mutants resulting in a complete loss of ovule initiation and a reduction of the structures ..

More Information


  1. Wynn A, Rueschhoff E, Franks R. Transcriptomic characterization of a synergistic genetic interaction during carpel margin meristem development in Arabidopsis thaliana. PLoS ONE. 2011;6:e26231 pubmed publisher
    ..When fertilized the ovules will develop into seeds. SEUSS (SEU) and AINTEGUMENTA (ANT) encode transcriptional regulators that are critical for the proper formation of ..
  2. Gong X, Flores Vergara M, Hong J, Chu H, Lim J, Franks R, et al. SEUSS Integrates Gibberellin Signaling with Transcriptional Inputs from the SHR-SCR-SCL3 Module to Regulate Middle Cortex Formation in the Arabidopsis Root. Plant Physiol. 2016;170:1675-83 pubmed publisher
    ..However, how their functions are regulated remains obscure. Here we show that mutations in the SEUSS (SEU) gene led to a higher frequency of MC formation...
  3. Smaczniak C, Immink R, MuiƱo J, Blanvillain R, Busscher M, Busscher Lange J, et al. Characterization of MADS-domain transcription factor complexes in Arabidopsis flower development. Proc Natl Acad Sci U S A. 2012;109:1560-5 pubmed publisher
    ..Furthermore, members of other transcription factor families were identified as interaction partners of floral MADS-domain proteins suggesting various specific combinatorial modes of action. ..
  4. Grigorova B, Mara C, Hollender C, Sijacic P, Chen X, Liu Z. LEUNIG and SEUSS co-repressors regulate miR172 expression in Arabidopsis flowers. Development. 2011;138:2451-6 pubmed publisher
    ..We show that the LEUNIG (LUG) and SEUSS (SEU) co-repressors repress miR172 expression in the outer whorls of A. thaliana flowers...
  5. Miller M, Barrett Wilt G, Hua Z, Vierstra R. Proteomic analyses identify a diverse array of nuclear processes affected by small ubiquitin-like modifier conjugation in Arabidopsis. Proc Natl Acad Sci U S A. 2010;107:16512-7 pubmed publisher
    ..Taken together, we propose that SUMOylation represents a rapid and global mechanism for reversibly manipulating plant chromosomal functions, especially during environmental stress. ..
  6. Stahle M, Kuehlich J, Staron L, von Arnim A, Golz J. YABBYs and the transcriptional corepressors LEUNIG and LEUNIG_HOMOLOG maintain leaf polarity and meristem activity in Arabidopsis. Plant Cell. 2009;21:3105-18 pubmed publisher
    ..transcriptional repressor complex that include LEUNIG (LUG), LEUNIG_HOMOLOG (LUH), the LUG-associated coregulator SEUSS, and related SEUSS-LIKE proteins...
  7. Lee J, Lampugnani E, Bacic A, Golz J. SEUSS and SEUSS-LIKE 2 coordinate auxin distribution and KNOXI activity during embryogenesis. Plant J. 2014;80:122-35 pubmed publisher
    In Arabidopsis, SEUSS (SEU) and SEUSS-LIKE 2 (SLK2) are components of the LEUNIG (LUG) repressor complex that coordinates various aspects of post-embryonic development...
  8. Franks R, Liu Z, Fischer R. SEUSS and LEUNIG regulate cell proliferation, vascular development and organ polarity in Arabidopsis petals. Planta. 2006;224:801-11 pubmed
    ..We have investigated the role of the SEUSS and LEUNIG genes in Arabidopsis thaliana (L.) Heynh...