Gene Symbol: SEP2
Description: K-box region and MADS-box transcription factor family protein
Alias: AGAMOUS-like 4, AGL4, F14P3.4, F14P3_4, SEPALLATA 2, TRANSCRIPTION FACTOR, K-box region and MADS-box transcription factor family protein
Species: thale cress
Ma H, Yanofsky M, Meyerowitz E. AGL1-AGL6, an Arabidopsis gene family with similarity to floral homeotic and transcription factor genes. Genes Dev. 1991;5:484-95 pubmed
..RNA dot blot analysis indicates that five of these genes (AGL1, AGL2, AGL4, AGL5, and AGL6) are preferentially expressed in flowers...
Favaro R, Pinyopich A, Battaglia R, Kooiker M, Borghi L, Ditta G, et al
. MADS-box protein complexes control carpel and ovule development in Arabidopsis. Plant Cell. 2003;15:2603-11 pubmed
..Together, these results indicate that the SEP proteins, which are known to form multimeric complexes in the control of flower organ identity, also form complexes to control normal ovule development. ..
Fan H, Hu Y, Tudor M, Ma H. Specific interactions between the K domains of AG and AGLs, members of the MADS domain family of DNA binding proteins. Plant J. 1997;12:999-1010 pubmed
..These clones each encode one of four highly related MADS domain proteins: AGL2, AGL4, AGL6 and AGL9...
Kaufmann K, Anfang N, Saedler H, Theissen G. Mutant analysis, protein-protein interactions and subcellular localization of the Arabidopsis B sister (ABS) protein. Mol Genet Genomics. 2005;274:103-18 pubmed
..These data suggest that the formation of multimeric transcription factor complexes might be a general phenomenon among MIKC-type MADS-domain proteins in angiosperms...
Jetha K, TheiÃŸen G, Melzer R. Arabidopsis SEPALLATA proteins differ in cooperative DNA-binding during the formation of floral quartet-like complexes. Nucleic Acids Res. 2014;42:10927-42 pubmed publisher
..However, SEP1 also bound strongly to CArG-box pairs separated by smaller or larger distances, whereas SEP2 preferred large and SEP4 preferred small inter-site distances for binding...
Li D, Fu X, Guo L, Huang Z, Li Y, Liu Y, et al
. FAR-RED ELONGATED HYPOCOTYL3 activates SEPALLATA2 but inhibits CLAVATA3 to regulate meristem determinacy and maintenance in Arabidopsis. Proc Natl Acad Sci U S A. 2016;113:9375-80 pubmed publisher
Plant meristems are responsible for the generation of all plant tissues and organs. Here we show that the transcription factor (TF) FAR-RED ELONGATED HYPOCOTYL3 (FHY3) plays an important role in both floral meristem (FM) determinacy and ..