Gene Symbol: SEP1
Description: K-box region and MADS-box transcription factor family protein
Alias: AGAMOUS-like 2, AGL2, F14F8.180, F14F8_180, SEPALLATA1, K-box region and MADS-box transcription factor family protein
Species: thale cress

Top Publications

  1. Flanagan C, Ma H. Spatially and temporally regulated expression of the MADS-box gene AGL2 in wild-type and mutant arabidopsis flowers. Plant Mol Biol. 1994;26:581-95 pubmed
    b>AGL2 is one of several Arabidopsis floral MADS-box genes that were isolated based on sequence similarity to the homeotic gene AGAMOUS...
  2. Favaro R, Pinyopich A, Battaglia R, Kooiker M, Borghi L, Ditta G, et al. MADS-box protein complexes control carpel and ovule development in Arabidopsis. Plant Cell. 2003;15:2603-11 pubmed
    ..Together, these results indicate that the SEP proteins, which are known to form multimeric complexes in the control of flower organ identity, also form complexes to control normal ovule development. ..
  3. Ma H, Yanofsky M, Meyerowitz E. AGL1-AGL6, an Arabidopsis gene family with similarity to floral homeotic and transcription factor genes. Genes Dev. 1991;5:484-95 pubmed
    ..RNA dot blot analysis indicates that five of these genes (AGL1, AGL2, AGL4, AGL5, and AGL6) are preferentially expressed in flowers...
  4. Huang H, Tudor M, Su T, Zhang Y, Hu Y, Ma H. DNA binding properties of two Arabidopsis MADS domain proteins: binding consensus and dimer formation. Plant Cell. 1996;8:81-94 pubmed
    ..MADS box genes confer their specific functions? Here, we describe results from DNA binding studies of AGL1 and AGL2 (for AGAMOUS-like), two Arabidopsis MADS domain proteins that are preferentially expressed in flowers...
  5. Fornara F, Parenicová L, Falasca G, Pelucchi N, Masiero S, Ciannamea S, et al. Functional characterization of OsMADS18, a member of the AP1/SQUA subfamily of MADS box genes. Plant Physiol. 2004;135:2207-19 pubmed
    ..Thus, when compared to AP1, OsMADS18 during evolution seems to have conserved the mechanistic properties of protein-protein interactions, although it cannot complement the AP1 function. ..
  6. Jetha K, Theißen G, Melzer R. Arabidopsis SEPALLATA proteins differ in cooperative DNA-binding during the formation of floral quartet-like complexes. Nucleic Acids Res. 2014;42:10927-42 pubmed publisher
    ..However, SEP1 also bound strongly to CArG-box pairs separated by smaller or larger distances, whereas SEP2 preferred large and ..
  7. Kaufmann K, Anfang N, Saedler H, Theissen G. Mutant analysis, protein-protein interactions and subcellular localization of the Arabidopsis B sister (ABS) protein. Mol Genet Genomics. 2005;274:103-18 pubmed
    ..Thus the evolutionary developmental genetics of B(sister) genes can probably only be understood as part of a complex and redundant gene network that may govern ovule formation in a conserved manner, which has yet to be fully explored. ..
  8. Fan H, Hu Y, Tudor M, Ma H. Specific interactions between the K domains of AG and AGLs, members of the MADS domain family of DNA binding proteins. Plant J. 1997;12:999-1010 pubmed
    ..These clones each encode one of four highly related MADS domain proteins: AGL2, AGL4, AGL6 and AGL9...
  9. Yang Y, Jack T. Defining subdomains of the K domain important for protein-protein interactions of plant MADS proteins. Plant Mol Biol. 2004;55:45-59 pubmed
    ..we report on our studies on the interactions of the B class MADS proteins AP3 and PI with the E class MADS proteins SEP1, SEP2, and SEP3...

More Information


  1. Yang Y, Xiang H, Jack T. pistillata-5, an Arabidopsis B class mutant with strong defects in petal but not in stamen development. Plant J. 2003;33:177-88 pubmed
    ..The decreased concentration of PI/AP3/SEP complexes offers an explanation for the petal defects observed in both pi-5 and 35S::SEP3 antisense plants. ..