Gene Symbol: SCL3
Description: scarecrow-like 3
Alias: F11F12.22, F11F12_22, SCARECROW-LIKE 3, SCL-3, scarecrow-like 3, scarecrow-like 3
Species: thale cress
Pysh L, Wysocka Diller J, Camilleri C, Bouchez D, Benfey P. The GRAS gene family in Arabidopsis: sequence characterization and basic expression analysis of the SCARECROW-LIKE genes. Plant J. 1999;18:111-9 pubmed
..The SCLs have distinct patterns of expression, but all of those analyzed show expression in the root. One of them, SCL3, has a tissue-specific pattern of expression in the root similar to SCR...
Gong X, Flores Vergara M, Hong J, Chu H, Lim J, Franks R, et al
. SEUSS Integrates Gibberellin Signaling with Transcriptional Inputs from the SHR-SCR-SCL3 Module to Regulate Middle Cortex Formation in the Arabidopsis Root. Plant Physiol. 2016;170:1675-83 pubmed publisher
..by several GRAS family transcription factors, including SHORT-ROOT (SHR), SCARECROW (SCR), and SCARECROW-LIKE3 (SCL3). However, how their functions are regulated remains obscure...
Yoshida H, Hirano K, Sato T, Mitsuda N, Nomoto M, Maeo K, et al
. DELLA protein functions as a transcriptional activator through the DNA binding of the indeterminate domain family proteins. Proc Natl Acad Sci U S A. 2014;111:7861-6 pubmed publisher
..family which bind physically to both DELLA and the promoter sequence of the GA-positive regulator SCARECROW-LIKE 3 (SCL3), which previously was characterized as a DELLA direct target gene...
Zentella R, Zhang Z, Park M, Thomas S, Endo A, Murase K, et al
. Global analysis of della direct targets in early gibberellin signaling in Arabidopsis. Plant Cell. 2007;19:3037-57 pubmed
..In addition, one of the putative DELLA targets, XERICO, promotes accumulation of abscisic acid (ABA) that antagonizes GA effects. Therefore, DELLA may restrict GA-promoted processes by modulating both GA and ABA pathways. ..
Yoshida H, Ueguchi Tanaka M. DELLA and SCL3 balance gibberellin feedback regulation by utilizing INDETERMINATE DOMAIN proteins as transcriptional scaffolds. Plant Signal Behav. 2014;9:e29726 pubmed publisher
..regulators in GA signaling, such as GA 20-oxidase, GA receptor, and a transcriptional regulator, SCARECROW-LIKE3 (SCL3), which enables the regulation of GA feedback...
Zhang Z, Ogawa M, Fleet C, Zentella R, Hu J, Heo J, et al
. Scarecrow-like 3 promotes gibberellin signaling by antagonizing master growth repressor DELLA in Arabidopsis. Proc Natl Acad Sci U S A. 2011;108:2160-5 pubmed publisher
..This study reveals an important step of the mechanism. Previous microarray studies identified scarecrow-like 3 (SCL3) as a direct target gene of DELLA in Arabidopsis seedlings. SCL3 expression is induced by DELLA and repressed by GA...
Cho Y, Yoo S, Sheen J. Regulatory functions of nuclear hexokinase1 complex in glucose signaling. Cell. 2006;127:579-89 pubmed
..The findings support a model in which conserved metabolic enzymes and proteins of well-established activities may perform previously unrecognized nuclear functions. ..