Gene Symbol: RUP2
Description: Transducin/WD40 repeat-like superfamily protein
Alias: EARLY FLOWERING BY OVEREXPRESSION 2, EFO2, MRO11.23, MRO11_23, REPRESSOR OF UV-B PHOTOMORPHOGENESIS 2, Transducin/WD40 repeat-like superfamily protein
Species: thale cress
Cloix C, Kaiserli E, Heilmann M, Baxter K, Brown B, O Hara A, et al
. C-terminal region of the UV-B photoreceptor UVR8 initiates signaling through interaction with the COP1 protein. Proc Natl Acad Sci U S A. 2012;109:16366-70 pubmed publisher
..Furthermore, we show that C27 interacts in yeast with the REPRESSOR OF UV-B PHOTOMORPHOGENESIS proteins, RUP1 and RUP2, which are negative regulators of UVR8 function. Hence the C27 region has a key role in UVR8 function.
Heijde M, Binkert M, Yin R, Ares Orpel F, Rizzini L, Van De Slijke E, et al
. Constitutively active UVR8 photoreceptor variant in Arabidopsis. Proc Natl Acad Sci U S A. 2013;110:20326-31 pubmed publisher
..Moreover, we have identified COP1, REPRESSOR OF UV-B PHOTOMORPHOGENESIS 1 and 2 (RUP1 and RUP2), and the SUPPRESSOR OF PHYA-105 (SPA) family as proteins copurifying with UVR8(W285A)...
Gruber H, Heijde M, Heller W, Albert A, Seidlitz H, Ulm R. Negative feedback regulation of UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis. Proc Natl Acad Sci U S A. 2010;107:20132-7 pubmed publisher
..Here, we describe two highly related WD40-repeat proteins, REPRESSOR OF UV-B PHOTOMORPHOGENESIS 1 (RUP1) and RUP2, that interact directly with UVR8 as potent repressors of UV-B signaling...
Heijde M, Ulm R. Reversion of the Arabidopsis UV-B photoreceptor UVR8 to the homodimeric ground state. Proc Natl Acad Sci U S A. 2013;110:1113-8 pubmed publisher
..We also demonstrate that the UVR8-interacting proteins repressor of UV-B photomorphogenesis (RUP)1 and RUP2 mediate UVR8 redimerization independently of COP1...
Ruckle M, Burgoon L, Lawrence L, Sinkler C, Larkin R. Plastids are major regulators of light signaling in Arabidopsis. Plant Physiol. 2012;159:366-90 pubmed publisher
..We conclude that the integration of light and plastid signaling regulates a number of END genes that help optimize chloroplast function and that at least some END genes affect photosynthesis-related gene expression...
Wang W, Yang D, Feldmann K. EFO1 and EFO2, encoding putative WD-domain proteins, have overlapping and distinct roles in the regulation of vegetative development and flowering of Arabidopsis. J Exp Bot. 2011;62:1077-88 pubmed publisher
..overexpression lines, two Arabidopsis genes were identified, EFO1 (early flowering by overexpression 1) and EFO2, that confer early flowering when overexpressed...
Yin R, Arongaus A, Binkert M, Ulm R. Two distinct domains of the UVR8 photoreceptor interact with COP1 to initiate UV-B signaling in Arabidopsis. Plant Cell. 2015;27:202-13 pubmed publisher
..further show, in contrast with COP1, that the WD40 repeat proteins REPRESSOR OF UV-B PHOTOMORPHOGENESIS1 (RUP1) and RUP2 interact only with the UVR8 C27 domain...
Huang X, Yang P, Ouyang X, Chen L, Deng X. Photoactivated UVR8-COP1 module determines photomorphogenic UV-B signaling output in Arabidopsis. PLoS Genet. 2014;10:e1004218 pubmed publisher
..Based on our molecular and biochemical evidence, we propose that the UVR8-COP1 affinity in plants critically determines the photomorphogenic UV-B signal transduction coupling with UVR8-mediated UV-B light perception. ..
Findlay K, Jenkins G. Regulation of UVR8 photoreceptor dimer/monomer photo-equilibrium in Arabidopsis plants grown under photoperiodic conditions. Plant Cell Environ. 2016;39:1706-14 pubmed publisher
..Experiments with mutants in REPRESSOR OF UV-B PHOTOMORPHOGENESIS 1 (RUP1) and RUP2 show that these proteins are crucial in regulating the photo-equilibrium because they promote reversion to the ..