RPB2

Summary

Gene Symbol: RPB2
Description: DNA-directed RNA polymerase family protein
Alias: EMB1989, EMBRYO DEFECTIVE 1989, F17L22.170, F17L22_170, RPB2, DNA-directed RNA polymerase family protein
Species: thale cress

Top Publications

  1. Kim Y, Zheng B, Yu Y, Won S, Mo B, Chen X. The role of Mediator in small and long noncoding RNA production in Arabidopsis thaliana. EMBO J. 2011;30:814-22 pubmed publisher
    ..This study expands the function of Mediator to include Pol II-mediated intergenic transcription and implicates a role of Mediator in genome stability. ..
  2. Oxelman B, Bremer B. Discovery of paralogous nuclear gene sequences coding for the second-largest subunit of RNA polymerase II (RPB2) and their phylogenetic utility in gentianales of the asterids. Mol Biol Evol. 2000;17:1131-45 pubmed
    Paralogous sequences of the RPB2 gene are demonstrated in the angiosperm order Gentianales...
  3. Ream T, Haag J, Wierzbicki A, Nicora C, Norbeck A, Zhu J, et al. Subunit compositions of the RNA-silencing enzymes Pol IV and Pol V reveal their origins as specialized forms of RNA polymerase II. Mol Cell. 2009;33:192-203 pubmed publisher
    ..Our findings support the hypothesis that Pol IV and Pol V are Pol II-like enzymes that evolved specialized roles in the production of noncoding transcripts for RNA silencing and genome defense. ..
  4. Fukudome A, Aksoy E, Wu X, Kumar K, Jeong I, May K, et al. Arabidopsis CPL4 is an essential C-terminal domain phosphatase that suppresses xenobiotic stress responses. Plant J. 2014;80:27-39 pubmed publisher
    ..Mass spectrometry analysis identified the pol II subunits RPB1, RPB2 and RPB3 in the affinity-purified CPL4 complex...
  5. Zhang S, Liu Y, Yu B. PRL1, an RNA-binding protein, positively regulates the accumulation of miRNAs and siRNAs in Arabidopsis. PLoS Genet. 2014;10:e1004841 pubmed publisher
    ..Based on these results, we propose that CDC5 and PRL1 cooperatively regulate pri-miRNA levels, which results in their synergistic effects on miRNA accumulation, while they function together as a complex to enhance DCL1 activity. ..
  6. Gonzalez N, Pauwels L, Baekelandt A, De Milde L, Van Leene J, Besbrugge N, et al. A Repressor Protein Complex Regulates Leaf Growth in Arabidopsis. Plant Cell. 2015;27:2273-87 pubmed publisher
    ..The identified conserved complex might be specific for leaf growth in the second dimension, since it is not present in Poaceae (grasses), which also lack the developmental program it controls. ..