Gene Symbol: ROPGEF4
Description: RHO guanyl-nucleotide exchange factor 4
Alias: ATROPGEF4, F4I18.13, GEF4, RHO GUANYL-NUCLEOTIDE EXCHANGE FACTOR 4, RHO guanyl-nucleotide exchange factor 4, RHS11, ROOT HAIR SPECIFIC 11, ROP (rho of plants) guanine nucleotide exchange factor 4, guanine exchange factor 4, RHO guanyl-nucleotide exchange factor 4
Species: thale cress

Top Publications

  1. Berken A, Thomas C, Wittinghofer A. A new family of RhoGEFs activates the Rop molecular switch in plants. Nature. 2005;436:1176-80 pubmed
    ..RopGEFs may represent the missing link in signal transduction from receptor kinases to Rops and their identification has implications for the evolution of the Rho molecular switch. ..
  2. Oikawa A, Joshi H, Rennie E, Ebert B, Manisseri C, Heazlewood J, et al. An integrative approach to the identification of Arabidopsis and rice genes involved in xylan and secondary wall development. PLoS ONE. 2010;5:e15481 pubmed publisher
  3. Gu Y, Li S, Lord E, Yang Z. Members of a novel class of Arabidopsis Rho guanine nucleotide exchange factors control Rho GTPase-dependent polar growth. Plant Cell. 2006;18:366-81 pubmed
    ..Green fluorescent protein-tagged RopGEF1 was localized to the tip of pollen tubes where ROP1 is activated. These results provide strong evidence that RopGEF1 activates ROP1 in control of polar growth in pollen tubes. ..
  4. Oda Y, Fukuda H. Initiation of cell wall pattern by a Rho- and microtubule-driven symmetry breaking. Science. 2012;337:1333-6 pubmed publisher
    ..By using a reconstitution assay, we revealed that ROPGEF4 (Rho of plant guanine nucleotide exchange factor 4) and ROPGAP3 [ROP guanosine triphosphatase (GTPase)-activating ..
  5. Qu S, Zhang X, Song Y, Lin J, Shan X. THESEUS1 positively modulates plant defense responses against Botrytis cinerea through GUANINE EXCHANGE FACTOR4 signaling. J Integr Plant Biol. 2017;59:797-804 pubmed publisher
    ..Here, we found that THE1 interacts with GUANINE EXCHANGE FACTOR4 (GEF4) and that both proteins play regulatory roles in plant resistance to the necrotrophic fungus Botrytis cinerea...
  6. Lin W, Liao Y, Yang T, Pan C, Buckhout T, Schmidt W. Coexpression-based clustering of Arabidopsis root genes predicts functional modules in early phosphate deficiency signaling. Plant Physiol. 2011;155:1383-402 pubmed publisher
    ..The combined results provide a novel, integrated view at a systems level of the root responses that acclimate Arabidopsis (Arabidopsis thaliana) to suboptimal Pi levels. ..
  7. Li Z, Liu D. ROPGEF1 and ROPGEF4 are functional regulators of ROP11 GTPase in ABA-mediated stomatal closure in Arabidopsis. FEBS Lett. 2012;586:1253-8 pubmed publisher
    ..In this study, we show that ROPGEF1 and ROPGEF4 interact with ROP11 on plasma membranes in guard cells...
  8. Yu F, Qian L, Nibau C, Duan Q, Kita D, Levasseur K, et al. FERONIA receptor kinase pathway suppresses abscisic acid signaling in Arabidopsis by activating ABI2 phosphatase. Proc Natl Acad Sci U S A. 2012;109:14693-8 pubmed publisher
    ..The FER pathway consists of a FER kinase interacting with guanine exchange factors GEF1, GEF4, and GEF10 that, in turn, activate GTPase ROP11/ARAC10...
  9. Huang G, Li E, Ge F, Li S, Wang Q, Zhang C, et al. Arabidopsis RopGEF4 and RopGEF10 are important for FERONIA-mediated developmental but not environmental regulation of root hair growth. New Phytol. 2013;200:1089-101 pubmed publisher
    ..thaliana, involving the receptor-like kinase FERONIA (FER), two guanine nucleotide exchange factors for ROPs (RopGEF4 and RopGEF10), and the small GTPase Rho of plants (ROPs)...