Gene Symbol: RIC4
Description: ROP-interactive CRIB motif-containing protein 4
Alias: MQK4.23, MQK4_23, ROP-interactive CRIB motif-containing protein 4, ROP-interactive CRIB motif-containing protein 4
Species: thale cress

Top Publications

  1. Wu G, Gu Y, Li S, Yang Z. A genome-wide analysis of Arabidopsis Rop-interactive CRIB motif-containing proteins that act as Rop GTPase targets. Plant Cell. 2001;13:2841-56 pubmed
    ..RIC3 (group III) and RIC4 (group V) both cause depolarized growth like Rop1 and display Rop1-enhanced localization to the tip of pollen tubes,..
  2. Gu Y, Fu Y, Dowd P, Li S, Vernoud V, Gilroy S, et al. A Rho family GTPase controls actin dynamics and tip growth via two counteracting downstream pathways in pollen tubes. J Cell Biol. 2005;169:127-38 pubmed
    ..shows that ROP1 activates two counteracting pathways involving the direct targets of tip-localized ROP1: RIC3 and RIC4. RIC4 promotes F-actin assembly, whereas RIC3 activates Ca(2+) signaling that leads to F-actin disassembly...
  3. Fu Y, Gu Y, Zheng Z, Wasteneys G, Yang Z. Arabidopsis interdigitating cell growth requires two antagonistic pathways with opposing action on cell morphogenesis. Cell. 2005;120:687-700 pubmed
    ..Locally activated ROP2, a Rho-related GTPase from plants, activates RIC4 to promote the assembly of cortical actin microfilaments required for localized outgrowth...
  4. Lee Y, Szumlanski A, Nielsen E, Yang Z. Rho-GTPase-dependent filamentous actin dynamics coordinate vesicle targeting and exocytosis during tip growth. J Cell Biol. 2008;181:1155-68 pubmed publisher
    The dynamic activity of tip-localized filamentous actin (F-actin) in pollen tubes is controlled by counteracting RIC4 and RIC3 pathways downstream of the ROP1 guanosine triphosphatase promoting actin assembly and disassembly, respectively...
  5. Oikawa A, Joshi H, Rennie E, Ebert B, Manisseri C, Heazlewood J, et al. An integrative approach to the identification of Arabidopsis and rice genes involved in xylan and secondary wall development. PLoS ONE. 2010;5:e15481 pubmed publisher