Gene Symbol: RDR1
Description: RNA-dependent RNA polymerase 1
Alias: ATRDRP1, AtRDR1, F10B6.19, F10B6_19, RNA-dependent RNA polymerase 1, RNA-dependent RNA polymerase 1
Species: thale cress
Xie Z, Johansen L, Gustafson A, Kasschau K, Lellis A, Zilberman D, et al
. Genetic and functional diversification of small RNA pathways in plants. PLoS Biol. 2004;2:E104 pubmed
..We conclude that proliferation and diversification of DCL and RDR genes during evolution of plants contributed to specialization of small RNA-directed pathways for development, chromatin structure, and defense. ..
Diaz Pendon J, Li F, Li W, Ding S. Suppression of antiviral silencing by cucumber mosaic virus 2b protein in Arabidopsis is associated with drastically reduced accumulation of three classes of viral small interfering RNAs. Plant Cell. 2007;19:2053-63 pubmed
..We found that production of CMV siRNAs without 2b interference depended largely on RNA-dependent RNA polymerase 1 (RDR1) inducible by SA...
Yu D, Fan B, MacFarlane S, Chen Z. Analysis of the involvement of an inducible Arabidopsis RNA-dependent RNA polymerase in antiviral defense. Mol Plant Microbe Interact. 2003;16:206-16 pubmed
..In the present study, we analyzed roles of a newly identified Arabidopsis RdRP gene (AtRdRP1) in plant antiviral defense...
Xu T, Zhang L, Zhen J, Fan Y, Zhang C, Wang L. Expressional and regulatory characterization of Arabidopsis RNA-dependent RNA polymerase 1. Planta. 2013;237:1561-9 pubmed publisher
..Histochemical staining and fluorescent signal detection revealed that AtRDR1 was expressed primarily in the plant vascular tissue system and its expression was specifically localized in ..
Garcia Ruiz H, Takeda A, Chapman E, Sullivan C, Fahlgren N, Brempelis K, et al
. Arabidopsis RNA-dependent RNA polymerases and dicer-like proteins in antiviral defense and small interfering RNA biogenesis during Turnip Mosaic Virus infection. Plant Cell. 2010;22:481-96 pubmed publisher
..revealed that the vast majority of virus-derived small interfering RNAs (siRNAs) were dependent on DCL4 and RDR1, although full antiviral defense also required DCL2 and RDR6...
Liao Y, Sun Z, Zhou Y, Shi K, Li X, Zhang G, et al
. The role of hydrogen peroxide and nitric oxide in the induction of plant-encoded RNA-dependent RNA polymerase 1 in the basal defense against Tobacco mosaic virus. PLoS ONE. 2013;8:e76090 pubmed publisher
Plant RNA-dependent RNA Polymerase 1 (RDR1) is an important element of the RNA silencing pathway in the plant defense against viruses...
Lam P, Zhao L, McFarlane H, Aiga M, Lam V, Hooker T, et al
. RDR1 and SGS3, components of RNA-mediated gene silencing, are required for the regulation of cuticular wax biosynthesis in developing inflorescence stems of Arabidopsis. Plant Physiol. 2012;159:1385-95 pubmed publisher