Gene Symbol: PRR7
Description: pseudo-response regulator 7
Alias: APRR7, F9G14.120, F9G14_120, pseudo-response regulator 7, pseudo-response regulator 7
Species: thale cress

Top Publications

  1. Kaczorowski K, Quail P. Arabidopsis PSEUDO-RESPONSE REGULATOR7 is a signaling intermediate in phytochrome-regulated seedling deetiolation and phasing of the circadian clock. Plant Cell. 2003;15:2654-65 pubmed
    ..lesions responsible for the phenotype were shown to be mutations in the Arabidopsis PSEUDO-RESPONSE REGULATOR7 (PRR7) gene...
  2. Matsushika A, Makino S, Kojima M, Mizuno T. Circadian waves of expression of the APRR1/TOC1 family of pseudo-response regulators in Arabidopsis thaliana: insight into the plant circadian clock. Plant Cell Physiol. 2000;41:1002-12 pubmed
    ..It was found that all these members of the APRR1/TOC1 family (APRR1, APRR3, APRR5, APRR7, and APRR9) are subjected to a circadian rhythm at the level of transcription...
  3. Salome P, McClung C. PSEUDO-RESPONSE REGULATOR 7 and 9 are partially redundant genes essential for the temperature responsiveness of the Arabidopsis circadian clock. Plant Cell. 2005;17:791-803 pubmed
    ..Here, we show that two PRR family members, PRR7 and PRR9, are partially redundant; single prr7-3 or prr9-1 mutants exhibit modest period lengthening, but the prr7-..
  4. Farré E, Kay S. PRR7 protein levels are regulated by light and the circadian clock in Arabidopsis. Plant J. 2007;52:548-60 pubmed
    ..Recent findings indicate that the TOC1 homologues PRR7 and PRR9 might also be involved in transcriptional regulatory loops with CCA1 and LHY...
  5. Nakamichi N, Kita M, Ito S, Yamashino T, Mizuno T. PSEUDO-RESPONSE REGULATORS, PRR9, PRR7 and PRR5, together play essential roles close to the circadian clock of Arabidopsis thaliana. Plant Cell Physiol. 2005;46:686-98 pubmed
    ..Nonetheless, it was not yet certain whether or not other PRR family members (PRR9, PRR7, PRR5 and PRR3) are implicated in clock function per se...
  6. Nakamichi N, Kita M, Niinuma K, Ito S, Yamashino T, Mizoguchi T, et al. Arabidopsis clock-associated pseudo-response regulators PRR9, PRR7 and PRR5 coordinately and positively regulate flowering time through the canonical CONSTANS-dependent photoperiodic pathway. Plant Cell Physiol. 2007;48:822-32 pubmed
    ..Here, we first showed that the clock-associated genes PSEUDO-RESPONSE REGULATOR (PRR) PRR9, PRR7 and PRR5 are involved in activation of CO expression during the daytime...
  7. Farré E, Harmer S, Harmon F, Yanovsky M, Kay S. Overlapping and distinct roles of PRR7 and PRR9 in the Arabidopsis circadian clock. Curr Biol. 2005;15:47-54 pubmed
    ..TOC1 is a member of the Arabidopsis circadian-regulated PRR gene family . Analysis of single and double mutants in PRR7 and PRR9 indicates that these morning-expressed genes play a dual role in the circadian clock, being involved in ..
  8. Salome P, Weigel D, McClung C. The role of the Arabidopsis morning loop components CCA1, LHY, PRR7, and PRR9 in temperature compensation. Plant Cell. 2010;22:3650-61 pubmed publisher
    ..We describe here the role of PSEUDO RESPONSE REGULATOR7 (PRR7) and PRR9 in temperature compensation...
  9. Kolmos E, Chow B, Pruneda Paz J, Kay S. HsfB2b-mediated repression of PRR7 directs abiotic stress responses of the circadian clock. Proc Natl Acad Sci U S A. 2014;111:16172-7 pubmed publisher
    ..Hsfs, including Heat Shock Factor B2b (HsfB2b), a transcriptional repressor that binds the promoter of Pseudo Response Regulator 7 (PRR7) at a conserved binding site...

More Information


  1. Ito S, Nakamichi N, Nakamura Y, Niwa Y, Kato T, Murakami M, et al. Genetic linkages between circadian clock-associated components and phytochrome-dependent red light signal transduction in Arabidopsis thaliana. Plant Cell Physiol. 2007;48:971-83 pubmed
    ..In addition, five members of a small family, PSEUDO-RESPONSE REGULATORS (including PRR1, PRR3, PRR5, PRR7 and PRR9), are believed to be another type of clock component...
  2. Higham C, Husmeier D. A Bayesian approach for parameter estimation in the extended clock gene circuit of Arabidopsis thaliana. BMC Bioinformatics. 2013;14 Suppl 10:S3 pubmed publisher
  3. Arana M, Tognacca R, Estravis Barcalá M, Sánchez R, Botto J. Physiological and molecular mechanisms underlying the integration of light and temperature cues in Arabidopsis thaliana seeds. Plant Cell Environ. 2017;40:3113-3121 pubmed publisher
    ..that the germination mediated by phytochrome B requires the presence of functional PSEUDO-RESPONSE REGULATOR 7 (PRR7) and TIMING OF CAB EXPRESSION 1 (TOC1) alleles...
  4. Nakamichi N, Kita M, Ito S, Sato E, Yamashino T, Mizuno T. The Arabidopsis pseudo-response regulators, PRR5 and PRR7, coordinately play essential roles for circadian clock function. Plant Cell Physiol. 2005;46:609-19 pubmed
    ..a small family of proteins, designated as ARABIDOPSIS PSEUDO-RESPONSE REGULATOR, including PRR1/TOC1, PRR3, PRR5, PRR7 and PRR9...
  5. Nakamichi N, Kiba T, Henriques R, Mizuno T, Chua N, Sakakibara H. PSEUDO-RESPONSE REGULATORS 9, 7, and 5 are transcriptional repressors in the Arabidopsis circadian clock. Plant Cell. 2010;22:594-605 pubmed publisher
    ..Genetic studies have suggested that PRR9, PRR7, and PRR5 also act within or close to the loop; however, their molecular functions remain unknown...
  6. Wang L, Kim J, Somers D. Transcriptional corepressor TOPLESS complexes with pseudoresponse regulator proteins and histone deacetylases to regulate circadian transcription. Proc Natl Acad Sci U S A. 2013;110:761-6 pubmed publisher
    ..PRR5, PRR7, and PRR9 can bind the promoters of the core clock genes circadian clock associated 1 (CCA1) and late elongated ..
  7. Liu T, Carlsson J, Takeuchi T, Newton L, Farr E. Direct regulation of abiotic responses by the Arabidopsis circadian clock component PRR7. Plant J. 2013;76:101-14 pubmed publisher
    ..Here, we show that PSEUDO-RESPONSE REGULATOR 7 (PRR7), a central component of the Arabidopsis clock, is directly involved in the repression of master regulators of ..