PRR5

Summary

Gene Symbol: PRR5
Description: two-component response regulator-like protein
Alias: APRR5, T31K7.5, T31K7_5, pseudo-response regulator 5, two-component response regulator-like protein
Species: thale cress

Top Publications

  1. Yamamoto Y, Sato E, Shimizu T, Nakamich N, Sato S, Kato T, et al. Comparative genetic studies on the APRR5 and APRR7 genes belonging to the APRR1/TOC1 quintet implicated in circadian rhythm, control of flowering time, and early photomorphogenesis. Plant Cell Physiol. 2003;44:1119-30 pubmed
    ..a member of a small family of proteins, designated as Arabidopsis PSEUDO-RESPONSE REGULATORS (APRR1/TOC1, APRR3, APRR5, APRR7, and APRR9)...
  2. Matsushika A, Makino S, Kojima M, Mizuno T. Circadian waves of expression of the APRR1/TOC1 family of pseudo-response regulators in Arabidopsis thaliana: insight into the plant circadian clock. Plant Cell Physiol. 2000;41:1002-12 pubmed
    ..It was found that all these members of the APRR1/TOC1 family (APRR1, APRR3, APRR5, APRR7, and APRR9) are subjected to a circadian rhythm at the level of transcription...
  3. Ito S, Nakamichi N, Nakamura Y, Niwa Y, Kato T, Murakami M, et al. Genetic linkages between circadian clock-associated components and phytochrome-dependent red light signal transduction in Arabidopsis thaliana. Plant Cell Physiol. 2007;48:971-83 pubmed
    ..In addition, five members of a small family, PSEUDO-RESPONSE REGULATORS (including PRR1, PRR3, PRR5, PRR7 and PRR9), are believed to be another type of clock component...
  4. Fujiwara S, Wang L, Han L, Suh S, Salome P, McClung C, et al. Post-translational regulation of the Arabidopsis circadian clock through selective proteolysis and phosphorylation of pseudo-response regulator proteins. J Biol Chem. 2008;283:23073-83 pubmed publisher
    ..Peak expression of TOC1 (timing of cab expression 1)/PRR1, PRR3, PRR5, PRR7, and PRR9 are each phased differently over the course of the day and loss of any PRR protein alters period...
  5. Matsushika A, Kawamura M, Nakamura Y, Kato T, Murakami M, Yamashino T, et al. Characterization of circadian-associated pseudo-response regulators: II. The function of PRR5 and its molecular dissection in Arabidopsis thaliana. Biosci Biotechnol Biochem. 2007;71:535-44 pubmed
    Together with PRR1/TOC1, PRR5 belongs to the small family of Pseudo-Response Regulators (PRRs), which function as clock components of Arabidopsis thaliana...
  6. Nakamichi N, Kita M, Ito S, Sato E, Yamashino T, Mizuno T. The Arabidopsis pseudo-response regulators, PRR5 and PRR7, coordinately play essential roles for circadian clock function. Plant Cell Physiol. 2005;46:609-19 pubmed
    ..of a small family of proteins, designated as ARABIDOPSIS PSEUDO-RESPONSE REGULATOR, including PRR1/TOC1, PRR3, PRR5, PRR7 and PRR9...
  7. Nakamichi N, Kiba T, Henriques R, Mizuno T, Chua N, Sakakibara H. PSEUDO-RESPONSE REGULATORS 9, 7, and 5 are transcriptional repressors in the Arabidopsis circadian clock. Plant Cell. 2010;22:594-605 pubmed publisher
    ..Genetic studies have suggested that PRR9, PRR7, and PRR5 also act within or close to the loop; however, their molecular functions remain unknown...
  8. Eriksson M, Hanano S, Southern M, Hall A, Millar A. Response regulator homologues have complementary, light-dependent functions in the Arabidopsis circadian clock. Planta. 2003;218:159-62 pubmed
    ..We show that prr9 and prr5 null mutants have reciprocal period defects for multiple circadian rhythms, consistent with subtly altered ..
  9. Kiba T, Henriques R, Sakakibara H, Chua N. Targeted degradation of PSEUDO-RESPONSE REGULATOR5 by an SCFZTL complex regulates clock function and photomorphogenesis in Arabidopsis thaliana. Plant Cell. 2007;19:2516-30 pubmed
    ..Using a PRR5-specific antibody, we characterized changes in PRR5 protein levels in relation to its mRNA levels under various ..
  10. Sato E, Nakamichi N, Yamashino T, Mizuno T. Aberrant expression of the Arabidopsis circadian-regulated APRR5 gene belonging to the APRR1/TOC1 quintet results in early flowering and hypersensitiveness to light in early photomorphogenesis. Plant Cell Physiol. 2002;43:1374-85 pubmed
    ..accumulating after dawn rhythmically and one after another at intervals in the order of APRR9-->APRR7-->APRR5-->APRR3-->APRR1/TOC1 under continuous light...

Detail Information

Publications30

  1. Yamamoto Y, Sato E, Shimizu T, Nakamich N, Sato S, Kato T, et al. Comparative genetic studies on the APRR5 and APRR7 genes belonging to the APRR1/TOC1 quintet implicated in circadian rhythm, control of flowering time, and early photomorphogenesis. Plant Cell Physiol. 2003;44:1119-30 pubmed
    ..a member of a small family of proteins, designated as Arabidopsis PSEUDO-RESPONSE REGULATORS (APRR1/TOC1, APRR3, APRR5, APRR7, and APRR9)...
  2. Matsushika A, Makino S, Kojima M, Mizuno T. Circadian waves of expression of the APRR1/TOC1 family of pseudo-response regulators in Arabidopsis thaliana: insight into the plant circadian clock. Plant Cell Physiol. 2000;41:1002-12 pubmed
    ..It was found that all these members of the APRR1/TOC1 family (APRR1, APRR3, APRR5, APRR7, and APRR9) are subjected to a circadian rhythm at the level of transcription...
  3. Ito S, Nakamichi N, Nakamura Y, Niwa Y, Kato T, Murakami M, et al. Genetic linkages between circadian clock-associated components and phytochrome-dependent red light signal transduction in Arabidopsis thaliana. Plant Cell Physiol. 2007;48:971-83 pubmed
    ..In addition, five members of a small family, PSEUDO-RESPONSE REGULATORS (including PRR1, PRR3, PRR5, PRR7 and PRR9), are believed to be another type of clock component...
  4. Fujiwara S, Wang L, Han L, Suh S, Salome P, McClung C, et al. Post-translational regulation of the Arabidopsis circadian clock through selective proteolysis and phosphorylation of pseudo-response regulator proteins. J Biol Chem. 2008;283:23073-83 pubmed publisher
    ..Peak expression of TOC1 (timing of cab expression 1)/PRR1, PRR3, PRR5, PRR7, and PRR9 are each phased differently over the course of the day and loss of any PRR protein alters period...
  5. Matsushika A, Kawamura M, Nakamura Y, Kato T, Murakami M, Yamashino T, et al. Characterization of circadian-associated pseudo-response regulators: II. The function of PRR5 and its molecular dissection in Arabidopsis thaliana. Biosci Biotechnol Biochem. 2007;71:535-44 pubmed
    Together with PRR1/TOC1, PRR5 belongs to the small family of Pseudo-Response Regulators (PRRs), which function as clock components of Arabidopsis thaliana...
  6. Nakamichi N, Kita M, Ito S, Sato E, Yamashino T, Mizuno T. The Arabidopsis pseudo-response regulators, PRR5 and PRR7, coordinately play essential roles for circadian clock function. Plant Cell Physiol. 2005;46:609-19 pubmed
    ..of a small family of proteins, designated as ARABIDOPSIS PSEUDO-RESPONSE REGULATOR, including PRR1/TOC1, PRR3, PRR5, PRR7 and PRR9...
  7. Nakamichi N, Kiba T, Henriques R, Mizuno T, Chua N, Sakakibara H. PSEUDO-RESPONSE REGULATORS 9, 7, and 5 are transcriptional repressors in the Arabidopsis circadian clock. Plant Cell. 2010;22:594-605 pubmed publisher
    ..Genetic studies have suggested that PRR9, PRR7, and PRR5 also act within or close to the loop; however, their molecular functions remain unknown...
  8. Eriksson M, Hanano S, Southern M, Hall A, Millar A. Response regulator homologues have complementary, light-dependent functions in the Arabidopsis circadian clock. Planta. 2003;218:159-62 pubmed
    ..We show that prr9 and prr5 null mutants have reciprocal period defects for multiple circadian rhythms, consistent with subtly altered ..
  9. Kiba T, Henriques R, Sakakibara H, Chua N. Targeted degradation of PSEUDO-RESPONSE REGULATOR5 by an SCFZTL complex regulates clock function and photomorphogenesis in Arabidopsis thaliana. Plant Cell. 2007;19:2516-30 pubmed
    ..Using a PRR5-specific antibody, we characterized changes in PRR5 protein levels in relation to its mRNA levels under various ..
  10. Sato E, Nakamichi N, Yamashino T, Mizuno T. Aberrant expression of the Arabidopsis circadian-regulated APRR5 gene belonging to the APRR1/TOC1 quintet results in early flowering and hypersensitiveness to light in early photomorphogenesis. Plant Cell Physiol. 2002;43:1374-85 pubmed
    ..accumulating after dawn rhythmically and one after another at intervals in the order of APRR9-->APRR7-->APRR5-->APRR3-->APRR1/TOC1 under continuous light...
  11. Nakamichi N, Kita M, Ito S, Yamashino T, Mizuno T. PSEUDO-RESPONSE REGULATORS, PRR9, PRR7 and PRR5, together play essential roles close to the circadian clock of Arabidopsis thaliana. Plant Cell Physiol. 2005;46:686-98 pubmed
    ..Nonetheless, it was not yet certain whether or not other PRR family members (PRR9, PRR7, PRR5 and PRR3) are implicated in clock function per se...
  12. Nakamichi N, Kita M, Niinuma K, Ito S, Yamashino T, Mizoguchi T, et al. Arabidopsis clock-associated pseudo-response regulators PRR9, PRR7 and PRR5 coordinately and positively regulate flowering time through the canonical CONSTANS-dependent photoperiodic pathway. Plant Cell Physiol. 2007;48:822-32 pubmed
    ..Here, we first showed that the clock-associated genes PSEUDO-RESPONSE REGULATOR (PRR) PRR9, PRR7 and PRR5 are involved in activation of CO expression during the daytime...
  13. Ito S, Niwa Y, Nakamichi N, Kawamura H, Yamashino T, Mizuno T. Insight into missing genetic links between two evening-expressed pseudo-response regulator genes TOC1 and PRR5 in the circadian clock-controlled circuitry in Arabidopsis thaliana. Plant Cell Physiol. 2008;49:201-13 pubmed publisher
    ..TOC1 encodes a member of the PSEUDO-RESPONSE REGULATOR (PRR) family, including PRR9, PRR7, PRR5, PRR3,and PRR1/TOC1...
  14. Wang L, Fujiwara S, Somers D. PRR5 regulates phosphorylation, nuclear import and subnuclear localization of TOC1 in the Arabidopsis circadian clock. EMBO J. 2010;29:1903-15 pubmed publisher
    ..Both TOC1 and a closely related protein, PRR5, are nuclear localized, expressed in the same phase, and shorten period when deficient, but their molecular ..
  15. Yasuhara M, Mitsui S, Hirano H, Takanabe R, Tokioka Y, Ihara N, et al. Identification of ASK and clock-associated proteins as molecular partners of LKP2 (LOV kelch protein 2) in Arabidopsis. J Exp Bot. 2004;55:2015-27 pubmed
    ..An interaction between LKP2 and APRR5, a paralogue of TOC1, was also observed, but LKP2 did not interact with APRR3, APRR7, or APRR9, other paralogues ..
  16. Fujimori T, Sato E, Yamashino T, Mizuno T. PRR5 (PSEUDO-RESPONSE REGULATOR 5) plays antagonistic roles to CCA1 (CIRCADIAN CLOCK-ASSOCIATED 1) in Arabidopsis thaliana. Biosci Biotechnol Biochem. 2005;69:426-30 pubmed
    ..have been characterizing a small family of proteins, designated ARABIDOPSIS PSEUDO-RESPONSE REGULATOR (PRR1, PRR3, PRR5, PRR7, and PRR9), based on the fact that one of the members (PRR1) is identical to TOC1...
  17. Takase M, Mizoguchi T, Kozuka T, Tsukaya H. The unique function of the Arabidopsis circadian clock gene PRR5 in the regulation of shade avoidance response. Plant Signal Behav. 2013;8:e23534 pubmed publisher
    ..A.R regulated by circadian clock. Expression analyses of S.A.R-related genes suggested that PRR5 functions as a repressor of S.A.R...
  18. Baudry A, Ito S, Song Y, Strait A, Kiba T, Lu S, et al. F-box proteins FKF1 and LKP2 act in concert with ZEITLUPE to control Arabidopsis clock progression. Plant Cell. 2010;22:606-22 pubmed publisher
    ..In addition, FKF1 and LKP2 also interacted with TIMING OF CAB EXPRESSION1 (TOC1) and PSEUDO-RESPONSE REGULATOR5 (PRR5), and both proteins were further stabilized in ztl fkf1 and ztl fkf1 lkp2 compared with in ztl...
  19. Li X, Ma D, Lu S, Hu X, Huang R, Liang T, et al. Blue Light- and Low Temperature-Regulated COR27 and COR28 Play Roles in the Arabidopsis Circadian Clock. Plant Cell. 2016;28:2755-2769 pubmed
    ..Finally, we report that COR27 and COR28 bind to the chromatin of TOC1 and PRR5 to repress their transcription, suggesting that their effects on rhythms are in part due to their regulation of ..
  20. Tepperman J, Hwang Y, Quail P. phyA dominates in transduction of red-light signals to rapidly responding genes at the initiation of Arabidopsis seedling de-etiolation. Plant J. 2006;48:728-42 pubmed
  21. Wang L, Kim J, Somers D. Transcriptional corepressor TOPLESS complexes with pseudoresponse regulator proteins and histone deacetylases to regulate circadian transcription. Proc Natl Acad Sci U S A. 2013;110:761-6 pubmed publisher
    ..b>PRR5, PRR7, and PRR9 can bind the promoters of the core clock genes circadian clock associated 1 (CCA1) and late ..
  22. Nakamichi N, Murakami Kojima M, Sato E, Kishi Y, Yamashino T, Mizuno T. Compilation and characterization of a novel WNK family of protein kinases in Arabiodpsis thaliana with reference to circadian rhythms. Biosci Biotechnol Biochem. 2002;66:2429-36 pubmed
    ..These results suggested that certain members of the WNK family of protein kinases might play roles in a mechanism that generates circadian rhythms in Arabidopsis. ..
  23. Xie Q, Wang P, Liu X, Yuan L, Wang L, Zhang C, et al. LNK1 and LNK2 are transcriptional coactivators in the Arabidopsis circadian oscillator. Plant Cell. 2014;26:2843-57 pubmed publisher
    ..been established as transcriptional activators of central clock components, including PSEUDO-RESPONSE REGULATOR5 (PRR5) and TIMING OF CAB EXPRESSION1 (TOC1)...
  24. Kawamura H, Ito S, Yamashino T, Niwa Y, Nakamichi N, Mizuno T. Characterization of genetic links between two clock-associated genes, GI and PRR5 in the current clock model of Arabidopsis thaliana. Biosci Biotechnol Biochem. 2008;72:2770-4 pubmed
    The GI (GIGANTEA) and PRR5 (PSEUDO-RESPONSE REGULATOR 5) genes are crucially implicated in the Arabidopsis circadian clock...
  25. Kamioka M, Takao S, Suzuki T, Taki K, Higashiyama T, Kinoshita T, et al. Direct Repression of Evening Genes by CIRCADIAN CLOCK-ASSOCIATED1 in the Arabidopsis Circadian Clock. Plant Cell. 2016;28:696-711 pubmed publisher
    ..Here, we demonstrate that direct regulation of PRR5 by CIRCADIAN CLOCK-ASSOCIATED1 (CCA1) determines the repression state of PRR5 in the morning...
  26. Giraud E, Ng S, Carrie C, Duncan O, Low J, Lee C, et al. TCP transcription factors link the regulation of genes encoding mitochondrial proteins with the circadian clock in Arabidopsis thaliana. Plant Cell. 2010;22:3921-34 pubmed publisher
  27. Rawat R, Takahashi N, Hsu P, Jones M, Schwartz J, Salemi M, et al. REVEILLE8 and PSEUDO-REPONSE REGULATOR5 form a negative feedback loop within the Arabidopsis circadian clock. PLoS Genet. 2011;7:e1001350 pubmed publisher
    ..Another key regulatory circuit involves CCA1 and LHY and the TOC1 homologs PRR5, PRR7, and PRR9...
  28. Higham C, Husmeier D. A Bayesian approach for parameter estimation in the extended clock gene circuit of Arabidopsis thaliana. BMC Bioinformatics. 2013;14 Suppl 10:S3 pubmed publisher
  29. Murakami Kojima M, Nakamichi N, Yamashino T, Mizuno T. The APRR3 component of the clock-associated APRR1/TOC1 quintet is phosphorylated by a novel protein kinase belonging to the WNK family, the gene for which is also transcribed rhythmically in Arabidopsis thaliana. Plant Cell Physiol. 2002;43:675-83 pubmed
    ..after dawn rhythmically and sequentially at approximately 2 h intervals in the order of APRR9-->APRR7-->APRR5-->APRR3-->APRR1/ TOC1...
  30. Ueoka Nakanishi H, Yamashino T, Ishida K, Kamioka M, Nakamichi N, Mizuno T. Molecular mechanisms of circadian rhythm in Lotus japonicus and Arabidopsis thaliana are sufficiently compatible to regulate heterologous core clock genes robustly. Biosci Biotechnol Biochem. 2012;76:2332-4 pubmed
    ..thaliana core clock genes CCA1 and PRR5 in heterologous L. japonicus cells and found that the molecular mechanism of circadian rhythm in L...