Gene Symbol: PKT3
Description: peroxisomal 3-ketoacyl-CoA thiolase 3
Alias: 3-KETOACYL-COA THIOLASE 2, KAT2, PED1, PEROXISOME DEFECTIVE 1, peroxisomal 3-ketoacyl-CoA thiolase 3, potassium channel in Arabidopsis thaliana 2, peroxisomal 3-ketoacyl-CoA thiolase 3
Species: thale cress

Top Publications

  1. He Y, Fukushige H, Hildebrand D, Gan S. Evidence supporting a role of jasmonic acid in Arabidopsis leaf senescence. Plant Physiol. 2002;128:876-84 pubmed
    ..transcript levels of 12-oxo-PDA reductase 1 and 12-oxo-PDA reductase 3 also increase in senescing leaves, as does PED1 (encoding a 3-keto-acyl-thiolase for beta-oxidation)...
  2. Castillo M, Leon J. Expression of the beta-oxidation gene 3-ketoacyl-CoA thiolase 2 (KAT2) is required for the timely onset of natural and dark-induced leaf senescence in Arabidopsis. J Exp Bot. 2008;59:2171-9 pubmed publisher
    ..activated expression of the gene coding for the JA-biosynthetic beta-oxidation enzyme 3-ketoacyl-CoA thiolase 2 (KAT2) in natural and dark-induced senescing leaves of Arabidopsis thaliana is reported here...
  3. Germain V, Rylott E, Larson T, Sherson S, Bechtold N, Carde J, et al. Requirement for 3-ketoacyl-CoA thiolase-2 in peroxisome development, fatty acid beta-oxidation and breakdown of triacylglycerol in lipid bodies of Arabidopsis seedlings. Plant J. 2001;28:1-12 pubmed
    ..Expression of the Arabidopsis thaliana KAT gene on chromosome 2 (KAT2), which encodes a peroxisomal thiolase, is activated in early seedling growth...
  4. Footitt S, Cornah J, Pracharoenwattana I, Bryce J, Smith S. The Arabidopsis 3-ketoacyl-CoA thiolase-2 (kat2-1) mutant exhibits increased flowering but reduced reproductive success. J Exp Bot. 2007;58:2959-68 pubmed
    ..3.1.16) catalyses a key step in fatty acid beta-oxidation. In Arabidopsis thaliana, expression of the KAT2 gene is known to be required for the efficient mobilization of triacylglycerol during germination and seedling ..
  5. Hayashi M, Toriyama K, Kondo M, Nishimura M. 2,4-Dichlorophenoxybutyric acid-resistant mutants of Arabidopsis have defects in glyoxysomal fatty acid beta-oxidation. Plant Cell. 1998;10:183-95 pubmed
    ..revealed that these mutants can be classified as carrying alleles at three independent loci, which we designated ped1, ped2, and ped3, respectively (where ped stands for peroxisome defective)...
  6. Eubel H, Meyer E, Taylor N, Bussell J, O Toole N, Heazlewood J, et al. Novel proteins, putative membrane transporters, and an integrated metabolic network are revealed by quantitative proteomic analysis of Arabidopsis cell culture peroxisomes. Plant Physiol. 2008;148:1809-29 pubmed publisher
  7. Wiszniewski A, Bussell J, Long R, Smith S. Knockout of the two evolutionarily conserved peroxisomal 3-ketoacyl-CoA thiolases in Arabidopsis recapitulates the abnormal inflorescence meristem 1 phenotype. J Exp Bot. 2014;65:6723-33 pubmed publisher
    ..Three genes encode peroxisomal 3-ketoacyl-CoA thiolase (KAT) in Arabidopsis. KAT2 and KAT5 are present throughout angiosperms whereas KAT1 is a Brassicaceae-specific duplication of KAT2 expressed ..
  8. Taylor N, Heazlewood J, Day D, Millar A. Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis. Plant Physiol. 2004;134:838-48 pubmed
    ..The potential role of branched-chain amino acid catabolism as an oxidative phosphorylation energy source or as a detoxification pathway during plant stress is discussed. ..
  9. Jiang T, Zhang X, Wang X, Zhang D. Arabidopsis 3-ketoacyl-CoA thiolase-2 (KAT2), an enzyme of fatty acid ?-oxidation, is involved in ABA signal transduction. Plant Cell Physiol. 2011;52:528-38 pubmed publisher
    ..Here, we report that an enzyme catalyzing ?-oxidation of fatty acids, 3-ketoacyl-CoA thiolase-2 (KAT2/PED1/PKT3) (EC, is involved in ABA signaling...