Gene Symbol: PGR5
Description: proton gradient regulation 5
Alias: AtPGR5, T20G20.3, T20G20_3, proton gradient regulation 5, proton gradient regulation 5
Species: thale cress

Top Publications

  1. Munekage Y, Genty B, Peltier G. Effect of PGR5 impairment on photosynthesis and growth in Arabidopsis thaliana. Plant Cell Physiol. 2008;49:1688-98 pubmed publisher
    b>PGR5 has been reported as an important factor for the activity of the ferredoxin-dependent cyclic electron transport around PSI...
  2. Nandha B, Finazzi G, Joliot P, Hald S, Johnson G. The role of PGR5 in the redox poising of photosynthetic electron transport. Biochim Biophys Acta. 2007;1767:1252-9 pubmed
    The pgr5 mutant of Arabidopsis thaliana has been described as being deficient in cyclic electron flow around photosystem I, however, the precise role of the PGR5 protein remains unknown...
  3. Long T, Okegawa Y, Shikanai T, Schmidt G, Covert S. Conserved role of proton gradient regulation 5 in the regulation of PSI cyclic electron transport. Planta. 2008;228:907-18 pubmed publisher
    ..Recent studies indicate that FQR-dependent CET is dependent upon PGR5, a small protein of unknown function...
  4. Munekage Y, Hojo M, Meurer J, Endo T, Tasaka M, Shikanai T. PGR5 is involved in cyclic electron flow around photosystem I and is essential for photoprotection in Arabidopsis. Cell. 2002;110:361-71 pubmed
    ..We isolated an Arabidopsis mutant, pgr5 (proton gradient regulation), in which downregulation of photosystem II photochemistry in response to intense light ..
  5. Hertle A, Blunder T, Wunder T, Pesaresi P, Pribil M, Armbruster U, et al. PGRL1 is the elusive ferredoxin-plastoquinone reductase in photosynthetic cyclic electron flow. Mol Cell. 2013;49:511-23 pubmed publisher
    ..exist in flowering plants, of which one is sensitive to antimycin A (AA) and involves the two thylakoid proteins, PGR5 and PGRL1...
  6. Sato R, Ohta H, Masuda S. Prediction of respective contribution of linear electron flow and PGR5-dependent cyclic electron flow to non-photochemical quenching induction. Plant Physiol Biochem. 2014;81:190-6 pubmed publisher
    ..The Arabidopsis CEF mutant, pgr5, showed significantly lower NPQ values than those observed in WT, indicating that ?pH, generated by the PGR5-..
  7. Suorsa M, Rossi F, Tadini L, Labs M, Colombo M, Jahns P, et al. PGR5-PGRL1-Dependent Cyclic Electron Transport Modulates Linear Electron Transport Rate in Arabidopsis thaliana. Mol Plant. 2016;9:271-288 pubmed publisher
    ..three sextuple mutants lacking the qE component of NPQ (Δ5 npq4-1), NDH-mediated CET (Δ5 crr4-3), or PGR5-PGRL1-mediated CET (Δ5 pgr5)...
  8. Okegawa Y, Long T, Iwano M, Takayama S, Kobayashi Y, Covert S, et al. A balanced PGR5 level is required for chloroplast development and optimum operation of cyclic electron transport around photosystem I. Plant Cell Physiol. 2007;48:1462-71 pubmed
    ..Although the thylakoid protein PGR5 (Proton Gradient Regulation 5) has been shown to be essential for the main route of PSI cyclic electron transport, its exact function ..
  9. Nellaepalli S, Kodru S, Raghavendra A, Subramanyam R. Antimycin A sensitive pathway independent from PGR5 cyclic electron transfer triggers non-photochemical reduction of PQ pool and state transitions in Arabidopsis thaliana. J Photochem Photobiol B. 2015;146:24-33 pubmed publisher
    ..Later, in pgr5 mutant, non-photochemical reduction of PQ pool was observed indicating the involvement of alternative electron ..

More Information


  1. DalCorso G, Pesaresi P, Masiero S, Aseeva E, Schünemann D, Finazzi G, et al. A complex containing PGRL1 and PGR5 is involved in the switch between linear and cyclic electron flow in Arabidopsis. Cell. 2008;132:273-85 pubmed publisher
    ..With the exception of PGR5, other components facilitating CEF are unknown...
  2. Okegawa Y, Kagawa Y, Kobayashi Y, Shikanai T. Characterization of factors affecting the activity of photosystem I cyclic electron transport in chloroplasts. Plant Cell Physiol. 2008;49:825-34 pubmed publisher
    ..Although a small thylakoid protein, PGR5 (PROTON GRADIENT REGULATION 5), is essential for this pathway, its function is still unclear, and there are numerous debates on the ..
  3. Suorsa M, Järvi S, Grieco M, Nurmi M, Pietrzykowska M, Rantala M, et al. PROTON GRADIENT REGULATION5 is essential for proper acclimation of Arabidopsis photosystem I to naturally and artificially fluctuating light conditions. Plant Cell. 2012;24:2934-48 pubmed publisher
    ..We showed that PROTON GRADIENT REGULATION5 (PGR5)-dependent regulation of electron transfer and proton motive force is crucial for protection of PSI against ..
  4. Sugimoto K, Okegawa Y, Tohri A, Long T, Covert S, Hisabori T, et al. A single amino acid alteration in PGR5 confers resistance to antimycin A in cyclic electron transport around PSI. Plant Cell Physiol. 2013;54:1525-34 pubmed publisher ruptured chloroplasts was less sensitive to antimycin A in Arabidopsis that overaccumulated PGR5 (PROTON GRADIENT REGULATION 5) originating from Pinus taeda (PtPGR5) than that in the wild type...