Gene Symbol: PGGT-I
Description: Prenyltransferase family protein
Species: thale cress

Top Publications

  1. Caldelari D, Sternberg H, Rodríguez Concepción M, Gruissem W, Yalovsky S. Efficient prenylation by a plant geranylgeranyltransferase-I requires a functional CaaL box motif and a proximal polybasic domain. Plant Physiol. 2001;126:1416-29 pubmed
  2. Johnson C, Chary S, Chernoff E, Zeng Q, Running M, Crowell D. Protein geranylgeranyltransferase I is involved in specific aspects of abscisic acid and auxin signaling in Arabidopsis. Plant Physiol. 2005;139:722-33 pubmed
    ..mutations in the Arabidopsis GGB gene, which encodes the beta-subunit of protein geranylgeranyltransferase type I (PGGT I)...
  3. Zeng Q, Wang X, Running M. Dual lipid modification of Arabidopsis Ggamma-subunits is required for efficient plasma membrane targeting. Plant Physiol. 2007;143:1119-31 pubmed
    ..Our data show the large degree to which PFT and PGGT-I can compensate for each other in plants and suggest that differential lipid modification plays an important regulatory role in plant protein localization. ..
  4. Andrews M, Huizinga D, Crowell D. The CaaX specificities of Arabidopsis protein prenyltransferases explain era1 and ggb phenotypes. BMC Plant Biol. 2010;10:118 pubmed publisher
    ..In contrast, ggb mutants lacking protein geranylgeranyltransferase type 1 exhibit subtle changes in ABA and auxin responsiveness, ..
  5. Sorek N, Gutman O, Bar E, Abu Abied M, Feng X, Running M, et al. Differential effects of prenylation and s-acylation on type I and II ROPS membrane interaction and function. Plant Physiol. 2011;155:706-20 pubmed publisher
    ..Taken together, our studies show how prenyl and S-acyl lipid modifications affect ROP subcellular distribution, membrane interaction dynamics, and function. ..