Gene Symbol: PDX2
Description: pyridoxine biosynthesis 2
Alias: ATPDX2, EMB2407, EMBRYO DEFECTIVE 2407, MUF9.1, MUF9_1, PYRIDOXINE BIOSYNTHESIS 2, pyridoxine biosynthesis 2, pyridoxine biosynthesis 2
Species: thale cress
Wagner S, Bernhardt A, Leuendorf J, Drewke C, Lytovchenko A, Mujahed N, et al
. Analysis of the Arabidopsis rsr4-1/pdx1-3 mutant reveals the critical function of the PDX1 protein family in metabolism, development, and vitamin B6 biosynthesis. Plant Cell. 2006;18:1722-35 pubmed
..In summary, our results demonstrate the critical function of the PDX1 protein family for metabolism, whole-plant development, and vitamin B6 biosynthesis in higher plants. ..
Tambasco Studart M, Tews I, Amrhein N, Fitzpatrick T. Functional analysis of PDX2 from Arabidopsis, a glutaminase involved in vitamin B6 biosynthesis. Plant Physiol. 2007;144:915-25 pubmed
..formation is catalyzed by a single glutamine amidotransferase (PLP synthase) composed of a glutaminase domain, PDX2, and a synthase domain, PDX1...
Tambasco Studart M, Titiz O, Raschle T, Forster G, Amrhein N, Fitzpatrick T. Vitamin B6 biosynthesis in higher plants. Proc Natl Acad Sci U S A. 2005;102:13687-92 pubmed
..on the recent discovery that, in bacteria and fungi, a novel pathway is in place that involves two genes (PDX1 and PDX2), neither of which is homologous to any of those involved in the previously doctrined E. coli pathway...
Leuendorf J, Genau A, Szewczyk A, Mooney S, Drewke C, Leistner E, et al
. The Pdx1 family is structurally and functionally conserved between Arabidopsis thaliana and Ginkgo biloba. FEBS J. 2008;275:960-9 pubmed publisher
..assays, we show that the protein can interact with itself and with members of Arabidopsis thaliana AtPDX1 and AtPDX2 families...