Gene Symbol: PCL1
Description: Homeodomain-like superfamily protein
Alias: LUX, LUX ARRHYTHMO, PHYTOCLOCK 1, Homeodomain-like superfamily protein
Species: thale cress

Top Publications

  1. Hazen S, Schultz T, Pruneda Paz J, Borevitz J, Ecker J, Kay S. LUX ARRHYTHMO encodes a Myb domain protein essential for circadian rhythms. Proc Natl Acad Sci U S A. 2005;102:10387-92 pubmed
    ..This screen identified five mutant alleles of a clock gene, LUX ARRHYTHMO (LUX), that significantly affect amplitude and robustness of rhythms in both constant white light and dark ..
  2. Nusinow D, Helfer A, Hamilton E, King J, Imaizumi T, Schultz T, et al. The ELF4-ELF3-LUX complex links the circadian clock to diurnal control of hypocotyl growth. Nature. 2011;475:398-402 pubmed publisher
    ..of the proteins encoded by EARLY FLOWERING 3 (ELF3), ELF4 and the transcription-factor-encoding gene LUX ARRHYTHMO (LUX; also known as PHYTOCLOCK 1)--that directly regulates plant growth...
  3. Onai K, Ishiura M. PHYTOCLOCK 1 encoding a novel GARP protein essential for the Arabidopsis circadian clock. Genes Cells. 2005;10:963-72 pubmed publisher
    ..for mutants with phenotypes of extensively altered circadian rhythms, and identified three loci, PHYTOCLOCK 1 (PCL1), PCL2 and PCL3, whose mutations cause arrhythmia...
  4. Helfer A, Nusinow D, Chow B, Gehrke A, Bulyk M, Kay S. LUX ARRHYTHMO encodes a nighttime repressor of circadian gene expression in the Arabidopsis core clock. Curr Biol. 2011;21:126-33 pubmed publisher
    ..Genetic screens previously identified LUX ARRHYTHMO (LUX) [5], also known as PHYTOCLOCK1 (PCL1) [6], an evening-expressed putative transcription factor essential ..
  5. Hsu P, Devisetty U, Harmer S. Accurate timekeeping is controlled by a cycling activator in Arabidopsis. elife. 2013;2:e00473 pubmed publisher
    ..Further, our work suggests that the plant clock consists of a highly interconnected, complex regulatory network rather than of coupled morning and evening feedback loops. DOI:http://dx.doi.org/10.7554/eLife.00473.001. ..
  6. Chow B, Sanchez S, Breton G, Pruneda Paz J, Krogan N, Kay S. Transcriptional regulation of LUX by CBF1 mediates cold input to the circadian clock in Arabidopsis. Curr Biol. 2014;24:1518-24 pubmed publisher
    ..To overcome these, we performed a high-throughput yeast one-hybrid screen using the LUX ARRYHTHMO (LUX) gene promoter as bait against an Arabidopsis TF library...
  7. Huang H, Yoo C, Bindbeutel R, Goldsworthy J, Tielking A, Alvarez S, et al. PCH1 integrates circadian and light-signaling pathways to control photoperiod-responsive growth in Arabidopsis. elife. 2016;5:e13292 pubmed publisher
    ..Thus, PCH1 is a new factor that regulates photoperiod-responsive growth by integrating the clock with light perception pathways through modulating daily phyB-signaling. ..
  8. Higham C, Husmeier D. A Bayesian approach for parameter estimation in the extended clock gene circuit of Arabidopsis thaliana. BMC Bioinformatics. 2013;14 Suppl 10:S3 pubmed publisher