Gene Symbol: NP1
Description: NPK1-related protein kinase 1
Alias: ANP1, F7G19.13, F7G19_13, MAP KINASE KINASE KINASE 1, MAPKKK1, NPK1-related protein kinase 1, NPK1-related protein kinase 1
Species: thale cress

Top Publications

  1. Nishihama R, Banno H, Kawahara E, Irie K, Machida Y. Possible involvement of differential splicing in regulation of the activity of Arabidopsis ANP1 that is related to mitogen-activated protein kinase kinase kinases (MAPKKKs). Plant J. 1997;12:39-48 pubmed
    ..of Arabidopsis cDNA (cANP1, cANP2 and cANP3) have been isolated that encode putative protein kinases, designated ANP1, ANP2 and ANP3...
  2. Krysan P, Jester P, Gottwald J, Sussman M. An Arabidopsis mitogen-activated protein kinase kinase kinase gene family encodes essential positive regulators of cytokinesis. Plant Cell. 2002;14:1109-20 pubmed
    ..Using a reverse-genetic approach, we isolated plants carrying knockout alleles of the Arabidopsis MAPKKK genes ANP1, ANP2, and ANP3...
  3. Sasabe M, Boudolf V, De Veylder L, Inze D, Genschik P, Machida Y. Phosphorylation of a mitotic kinesin-like protein and a MAPKKK by cyclin-dependent kinases (CDKs) is involved in the transition to cytokinesis in plants. Proc Natl Acad Sci U S A. 2011;108:17844-9 pubmed publisher
    ..Thus, timely and coordinated phosphorylation by CDKs and dephosphorylation of cytokinetic regulators from prophase to anaphase appear to be critical for the appropriate onset and/or progression of cytokinesis. ..
  4. Kovtun Y, Chiu W, Tena G, Sheen J. Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants. Proc Natl Acad Sci U S A. 2000;97:2940-5 pubmed
    ..assay, we show that H(2)O(2) can activate a specific Arabidopsis mitogen-activated protein kinase kinase kinase, ANP1, which initiates a phosphorylation cascade involving two stress MAPKs, AtMPK3 and AtMPK6...