Gene Symbol: NAP1;2
Description: nucleosome assembly protein 1;2
Alias: F3P11.8, F3P11_8, NFA02, NFA2, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP A 02, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP A 2, nucleosome assembly protein 1;2, nucleosome assembly protein 1;2
Species: thale cress
Zhou W, Gao J, Ma J, Cao L, Zhang C, Zhu Y, et al
. Distinct roles of the histone chaperones NAP1 and NRP and the chromatin-remodeling factor INO80 in somatic homologous recombination in Arabidopsis thaliana. Plant J. 2016;88:397-410 pubmed publisher
..X (?-H2A.X) are not impaired in the mutants. Collectively, our study indicates that NRP and AtNAP1 synergistically promote HR upstream of AtINO80-mediated chromatin remodeling after the formation of ?-H2A.X foci during DNA damage repair. ..
Crane Y, Gelvin S. RNAi-mediated gene silencing reveals involvement of Arabidopsis chromatin-related genes in Agrobacterium-mediated root transformation. Proc Natl Acad Sci U S A. 2007;104:15156-61 pubmed
..response to three transformation assays (HAG3, HDT1, HDA15, CHR1, HAC1, HON5, HDT2, GTE2, GTE4, GTE7, HDA19, HAF1, NFA2, NFA3, SGA1, and SGB2); or (iii) varying response among the three transformation assays (DMT1, DMT2, DMT4, SDG1, ..
Liu Z, Zhu Y, Gao J, Yu F, Dong A, Shen W. Molecular and reverse genetic characterization of NUCLEOSOME ASSEMBLY PROTEIN1 (NAP1) genes unravels their function in transcription and nucleotide excision repair in Arabidopsis thaliana. Plant J. 2009;59:27-38 pubmed publisher
..Taken together, our results highlight conserved and isoform-specific properties of AtNAP1 proteins, and unravel their function in the NER pathway of DNA damage repair. ..
Liu Z, Gao J, Dong A, Shen W. A truncated Arabidopsis NUCLEOSOME ASSEMBLY PROTEIN 1, AtNAP1;3T, alters plant growth responses to abscisic acid and salt in the Atnap1;3-2 mutant. Mol Plant. 2009;2:688-699 pubmed publisher
..Taken together, our study uncovered AtNAP1 proteins as positive regulators and AtNAP1;3T as a negative regulator in ABA signaling pathways, providing a novel link of chromatin remodeling to hormonal and stress responses. ..
Son O, Kim S, Shin Y, Kim W, Koh H, Cheon C. Identification of nucleosome assembly protein 1 (NAP1) as an interacting partner of plant ribosomal protein S6 (RPS6) and a positive regulator of rDNA transcription. Biochem Biophys Res Commun. 2015;465:200-5 pubmed publisher
Budhiraja R, Hermkes R, Muller S, Schmidt J, Colby T, Panigrahi K, et al
. Substrates related to chromatin and to RNA-dependent processes are modified by Arabidopsis SUMO isoforms that differ in a conserved residue with influence on desumoylation. Plant Physiol. 2009;149:1529-40 pubmed publisher
..The majority of the identified bona fide substrates contain predicted sumoylation sites. A subset of the proteins was expressed in Escherichia coli and could be sumoylated in vitro. ..
Okada S, Nagabuchi M, Takamura Y, Nakagawa T, Shinmyozu K, Nakayama J, et al
. Reconstitution of Arabidopsis thaliana SUMO pathways in E. coli: functional evaluation of SUMO machinery proteins and mapping of SUMOylation sites by mass spectrometry. Plant Cell Physiol. 2009;50:1049-61 pubmed publisher
..This system will be a powerful tool for elucidation of the role of SUMOylation and of the biochemical and structural features of SUMOylated proteins in plants. ..
Gao J, Zhu Y, Zhou W, Molinier J, Dong A, Shen W. NAP1 family histone chaperones are required for somatic homologous recombination in Arabidopsis. Plant Cell. 2012;24:1437-47 pubmed publisher
..Our study highlights distinct functions for different families of histone chaperones in the maintenance of genome stability and establishes a crucial function for NAP1 family histone chaperones in somatic HR. ..