Gene Symbol: MUR4
Description: NAD(P)-binding Rossmann-fold superfamily protein
Alias: HIGH SUGAR RESPONSE8, HSR8, MURUS 4, T5I8.7, T5I8_7, UDP-D-XYLOSE 4-EPIMERASE 1, UXE1, NAD(P)-binding Rossmann-fold superfamily protein
Species: thale cress

Top Publications

  1. Burget E, Verma R, Mølhøj M, Reiter W. The biosynthesis of L-arabinose in plants: molecular cloning and characterization of a Golgi-localized UDP-D-xylose 4-epimerase encoded by the MUR4 gene of Arabidopsis. Plant Cell. 2003;15:523-31 pubmed
    The mur4 mutant of Arabidopsis shows a 50% reduction in the monosaccharide L-Ara in leaf-derived cell wall material because of a partial defect in the 4-epimerization of UDP-D-Xyl to UDP-L-Ara...
  2. Seguela Arnaud M, Smith C, Uribe M, May S, Fischl H, McKenzie N, et al. The Mediator complex subunits MED25/PFT1 and MED8 are required for transcriptional responses to changes in cell wall arabinose composition and glucose treatment in Arabidopsis thaliana. BMC Plant Biol. 2015;15:215 pubmed publisher
    ..of the Mediator transcription complex suppressed the sugar-hypersensitive hypocotyl elongation phenotype of the hsr8-1 mutant, which has cell wall defects due to arabinose deficiency that do not permit normal cell elongation...
  3. Reiter W, Chapple C, Somerville C. Mutants of Arabidopsis thaliana with altered cell wall polysaccharide composition. Plant J. 1997;12:335-45 pubmed
    ..Mutants with reductions in a single monosaccharide have been identified for fucose (mur2, mur3), arabinose (mur4, mur5, mur6, mur7), and rhamnose (mur8)...
  4. Li Y, Smith C, Corke F, Zheng L, Merali Z, Ryden P, et al. Signaling from an altered cell wall to the nucleus mediates sugar-responsive growth and development in Arabidopsis thaliana. Plant Cell. 2007;19:2500-15 pubmed
    ..the molecular mechanisms of sugar responses, we isolated and characterized an Arabidopsis thaliana mutant, high sugar response8 (hsr8), which enhances sugar-responsive growth and gene expression...
  5. Burget E, Reiter W. The mur4 mutant of arabidopsis is partially defective in the de novo synthesis of uridine diphospho L-arabinose. Plant Physiol. 1999;121:383-9 pubmed
    To obtain information on the synthesis and function of arabinosylated glycans, the mur4 mutant of Arabidopsis was characterized...