Genomes and Genes
Gene Symbol: MKK4
Description: mitogen-activated protein kinase kinase 4
Alias: ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4, ATMEK4, ATMKK4, F19C24.26, F19C24_26, MAP KINASE KINASE 4, mitogen-activated protein kinase kinase 4, mitogen-activated protein kinase kinase 4
Species: thale cress
- Samuel M, Chaal B, Lampard G, Green B, Ellis B. Surviving the passage: Non-canonical stromal targeting of an Arabidopsis mitogen-activated protein kinase kinase. Plant Signal Behav. 2008;3:6-12 pubmed..In vitro uptake experiments confirm the predicted import of an oxidant-responsive MAPKK, AtMKK4, into the chloroplast...
- Zhao C, Nie H, Shen Q, Zhang S, Lukowitz W, Tang D. EDR1 physically interacts with MKK4/MKK5 and negatively regulates a MAP kinase cascade to modulate plant innate immunity. PLoS Genet. 2014;10:e1004389 pubmed publisher..Here, we showed that EDR1 negatively regulates the MKK4/MKK5-MPK3/MPK6 kinase cascade in Arabidopsis...
- Yamada K, Yamaguchi K, Shirakawa T, Nakagami H, Mine A, Ishikawa K, et al. The Arabidopsis CERK1-associated kinase PBL27 connects chitin perception to MAPK activation. EMBO J. 2016;35:2468-2483 pubmed..These data indicate that PBL27 is the MAPKKK kinase that provides the missing link between the cell surface chitin receptor and the intracellular MAPK cascade in plants. ..
- Cho S, Larue C, Chevalier D, Wang H, Jinn T, Zhang S, et al. Regulation of floral organ abscission in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2008;105:15629-34 pubmed publisher..receptor-like protein kinases HAESA (HAE) and HAESA-like 2 (HSL2), the Mitogen-Activated Protein Kinase Kinase 4 (MKK4) and MKK5, and a dominant-negative form of Mitogen-Activated Protein Kinase 6 (MPK6) in a mpk3 mutant background ..
- Patharkar O, Walker J. Floral organ abscission is regulated by a positive feedback loop. Proc Natl Acad Sci U S A. 2015;112:2906-11 pubmed publisher..This study helps define the mechanisms and regulatory networks involved in a receptor-mediated signaling pathway that controls floral organ abscission. ..