Gene Symbol: MAF1
Description: K-box region and MADS-box transcription factor family protein
Alias: AGAMOUS-like 27, AGL27, FLM, FLOWERING LOCUS M, MADS AFFECTING FLOWERING 1, K-box region and MADS-box transcription factor family protein
Species: thale cress

Top Publications

  1. Ratcliffe O, Nadzan G, Reuber T, Riechmann J. Regulation of flowering in Arabidopsis by an FLC homologue. Plant Physiol. 2001;126:122-32 pubmed
    ..We have isolated an Arabidopsis gene, MAF1, which encodes a protein that is closely related to FLC...
  2. Pelaz S, Gustafson Brown C, Kohalmi S, Crosby W, Yanofsky M. APETALA1 and SEPALLATA3 interact to promote flower development. Plant J. 2001;26:385-94 pubmed
    ..Taken together, these studies suggest that SEP3 interacts with AP1 to promote normal flower development. ..
  3. Airoldi C, McKay M, Davies B. MAF2 Is Regulated by Temperature-Dependent Splicing and Represses Flowering at Low Temperatures in Parallel with FLM. PLoS ONE. 2015;10:e0126516 pubmed publisher
    ..SVP binds DNA in complexes with other MADS-box transcription factors, including FLOWERING LOCUS M (FLM), which acts with SVP to repress the floral transition at low temperatures...
  4. Sureshkumar S, Dent C, Seleznev A, Tasset C, Balasubramanian S. Nonsense-mediated mRNA decay modulates FLM-dependent thermosensory flowering response in Arabidopsis. Nat Plants. 2016;2:16055 pubmed publisher
    ..of FLOWERING LOCUS T (FT) by transcription factor PHYTOCHROME INTERACTING FACTOR 4 (PIF4) or the FLOWERING LOCUS M (FLM)-SHORT VEGETATIVE PHASE (SVP) complex, respectively, have been suggested to be involved(3-6)...
  5. Hwan Lee J, Sook Chung K, Kim S, Ahn J. Post-translational regulation of short vegetative phase as a major mechanism for thermoregulation of flowering. Plant Signal Behav. 2014;9:e28193 pubmed
    ..Recent reports revealed that flowering locus M (FLM) and short vegetative phase (SVP) regulate high ambient temperature-responsive flowering through two ..
  6. Lutz U, Posé D, Pfeifer M, Gundlach H, Hagmann J, Wang C, et al. Modulation of Ambient Temperature-Dependent Flowering in Arabidopsis thaliana by Natural Variation of FLOWERING LOCUS M. PLoS Genet. 2015;11:e1005588 pubmed publisher
    ..In Arabidopsis thaliana, FLOWERING LOCUS M (FLM) is a critical flowering regulator of the ambient temperature pathway...
  7. Posé D, Verhage L, Ott F, Yant L, Mathieu J, Angenent G, et al. Temperature-dependent regulation of flowering by antagonistic FLM variants. Nature. 2013;503:414-7 pubmed publisher
    ..In Arabidopsis thaliana, the MADS-box transcription factor genes FLOWERING LOCUS M (FLM) and SHORT VEGETATIVE PHASE (SVP) have key roles in this process...
  8. Pouteau S, Carré I, Gaudin V, Ferret V, Lefebvre D, Wilson M. Diversification of photoperiodic response patterns in a collection of early-flowering mutants of Arabidopsis. Plant Physiol. 2008;148:1465-73 pubmed publisher
    ..Furthermore, the frequency of circadian defects in mutants with normal photoperiodic responses suggested that the circadian clock may regulate the number of leaves independently of its effect on daylength perception. ..
  9. Khan M, Khan I, Ali G. MPF2-like MADS-box genes affecting expression of SOC1 and MAF1 are recruited to control flowering time. Mol Biotechnol. 2013;54:25-36 pubmed publisher
    ..effects on the expression of SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1, a floral promoter) and MADS AFFECTING FLOWERING 1 (MAF1, a floral repressor) genes...

More Information


  1. Alvarez Buylla E, Liljegren S, Pelaz S, Gold S, Burgeff C, Ditta G, et al. MADS-box gene evolution beyond flowers: expression in pollen, endosperm, guard cells, roots and trichomes. Plant J. 2000;24:457-66 pubmed
    ..and mRNA spatio-temporal expression patterns of five new MADS-box genes from Arabidopsis: AGL16, AGL18, AGL19, AGL27 and AGL31...
  2. MacLean A, Orlovskis Z, Kowitwanich K, Zdziarska A, Angenent G, Immink R, et al. Phytoplasma effector SAP54 hijacks plant reproduction by degrading MADS-box proteins and promotes insect colonization in a RAD23-dependent manner. PLoS Biol. 2014;12:e1001835 pubmed publisher
  3. Lee J, Ryu H, Chung K, Posé D, Kim S, Schmid M, et al. Regulation of temperature-responsive flowering by MADS-box transcription factor repressors. Science. 2013;342:628-32 pubmed publisher
    ..Here, we show that levels of FLM-?, an alternatively spliced form of the flowering repressor FLOWERING LOCUS M, increase at lower temperatures, repressing flowering...
  4. Werner J, Borevitz J, Warthmann N, Trainer G, Ecker J, Chory J, et al. Quantitative trait locus mapping and DNA array hybridization identify an FLM deletion as a cause for natural flowering-time variation. Proc Natl Acad Sci U S A. 2005;102:2460-5 pubmed
    ..of largest effect, termed FLOWERING 1 (FLW1), was found to be associated with a Nd-specific deletion of FLOWERING LOCUS M (FLM), which encodes a floral repressor closely related to FLC...