Gene Symbol: LTI78
Description: low-temperature-responsive protein 78 (LTI78) / desiccation-responsive protein 29A (RD29A)
Alias: COLD REGULATED 78, COR78, K24M7.4, K24M7_4, LOW-TEMPERATURE-INDUCED 78, LTI140, RD29A, RESPONSIVE TO DESSICATION 29A, low-temperature-responsive protein 78 (LTI78) / desiccation-responsive protein 29A (RD29A)
Species: thale cress

Top Publications

  1. Msanne J, Lin J, Stone J, Awada T. Characterization of abiotic stress-responsive Arabidopsis thaliana RD29A and RD29B genes and evaluation of transgenes. Planta. 2011;234:97-107 pubmed publisher
    Abiotic stresses have adverse effects on plant growth and productivity. The homologous RD29A and RD29B genes are exquisitely sensitive to various abiotic stressors...
  2. Narusaka Y, Nakashima K, Shinwari Z, Sakuma Y, Furihata T, Abe H, et al. Interaction between two cis-acting elements, ABRE and DRE, in ABA-dependent expression of Arabidopsis rd29A gene in response to dehydration and high-salinity stresses. Plant J. 2003;34:137-48 pubmed
    ..We precisely analyzed the 120 bp promoter region (-174 to -55) of the Arabidopsis rd29A gene whose expression is induced by dehydration, high-salinity, low-temperature, and abscisic acid (ABA) ..
  3. Kim J, To T, Ishida J, Morosawa T, Kawashima M, Matsui A, et al. Alterations of lysine modifications on the histone H3 N-tail under drought stress conditions in Arabidopsis thaliana. Plant Cell Physiol. 2008;49:1580-8 pubmed publisher
    ..H3K23ac and H3K27ac in the histone H3 N-tail on the regions of four Arabidopsis drought stress-inducible genes, RD29A, RD29B, RD20 and At2g20880 [corrected], under drought stress conditions by chromatin immunoprecipitation analysis...
  4. Xiong L, Lee H, Ishitani M, Zhu J. Regulation of osmotic stress-responsive gene expression by the LOS6/ABA1 locus in Arabidopsis. J Biol Chem. 2002;277:8588-96 pubmed
    ..RNA blot analysis indicates that under osmotic stress the transcript levels for stress-responsive genes such as RD29A, COR15A, KIN1, COR47, RD19, and ADH are lower in los6 plants than in wild type plants...
  5. Vergnolle C, Vaultier M, Taconnat L, Renou J, Kader J, Zachowski A, et al. The cold-induced early activation of phospholipase C and D pathways determines the response of two distinct clusters of genes in Arabidopsis cell suspensions. Plant Physiol. 2005;139:1217-33 pubmed
    ..The connection of these pathways with the CBF pathway, currently the most understood genetic system playing a role in cold acclimation, is discussed. ..
  6. Lee S, Boon N, Webb A, Tanaka R. Synergistic Activation of RD29A Via Integration of Salinity Stress and Abscisic Acid in Arabidopsis thaliana. Plant Cell Physiol. 2016;57:2147-2160 pubmed
    ..We measured dynamics of Response-to-Dehydration 29A (RD29A) expression induced by single or combined NaCl and ABA treatments in Arabidopsis thaliana...
  7. Bihmidine S, Lin J, Stone J, Awada T, Specht J, Clemente T. Activity of the Arabidopsis RD29A and RD29B promoter elements in soybean under water stress. Planta. 2013;237:55-64 pubmed publisher
    The constitutive and drought-induced activities of the Arabidopsis thaliana RD29A and RD29B promoters were monitored in soybean (Glycine max (L.) Merr.] via fusions with the visual marker gene ?-glucuronidase (GUS)...
  8. Nordin K, Vahala T, Palva E. Differential expression of two related, low-temperature-induced genes in Arabidopsis thaliana (L.) Heynh. Plant Mol Biol. 1993;21:641-53 pubmed
    ..The nucleotide sequences of the two genes, lti78 and lti65, predict novel hydrophilic polypeptides with molecular weights of 77,856 and 64,510, respectively, lti78 ..
  9. Knight H, Trewavas A, Knight M. Calcium signalling in Arabidopsis thaliana responding to drought and salinity. Plant J. 1997;12:1067-78 pubmed
    ..Data obtained by using inhibitors of inositol signalling suggested that this release was occurring through IP3-dependent calcium channels. ..

More Information


  1. Kim J, To T, Ishida J, Matsui A, Kimura H, Seki M. Transition of chromatin status during the process of recovery from drought stress in Arabidopsis thaliana. Plant Cell Physiol. 2012;53:847-56 pubmed publisher
    ..status toward gene repression during the process of recovery from drought stress of drought-inducible genes (RD20, RD29A and AtGOLS2) and a rehydration-inducible gene (ProDH)...
  2. Rayirath P, Benkel B, Mark Hodges D, Allan Wojtas P, MacKinnon S, Critchley A, et al. Lipophilic components of the brown seaweed, Ascophyllum nodosum, enhance freezing tolerance in Arabidopsis thaliana. Planta. 2009;230:135-47 pubmed publisher
    ..Further, the A. nodosum extract treatment modulated the expression of the cold response genes, COR15A, RD29A, and CBF3, resulting in enhanced tolerance to freezing temperatures. More than 2...
  3. Lee Y, Fleming A, Körner C, Meins F. Differential expression of the CBF pathway and cell cycle-related genes in Arabidopsis accessions in response to chronic low-temperature exposure. Plant Biol (Stuttg). 2009;11:273-83 pubmed publisher
    ..chronic) effects of low, non-freezing temperatures on the expression of CBF pathway genes (CBF2/3, COR15a, RD29A) and cell cycle-related genes (CDKA;1, CYCD2;1, CYCB1;1) in roots of accessions from habitats differing in growing ..
  4. Yang S, Seo P, Yoon H, Park C. The Arabidopsis NAC transcription factor VNI2 integrates abscisic acid signals into leaf senescence via the COR/RD genes. Plant Cell. 2011;23:2155-68 pubmed publisher
    ..These observations indicate that the VNI2 transcription factor serves as a molecular link that integrates plant responses to environmental stresses into modulation of leaf longevity. ..
  5. Alet A, Sanchez D, Ferrando A, Tiburcio A, Alcázar R, Cuevas J, et al. Homeostatic control of polyamine levels under long-term salt stress in Arabidopsis: changes in putrescine content do not alleviate ionic toxicity. Plant Signal Behav. 2011;6:237-42 pubmed
  6. Yang T, Chaudhuri S, Yang L, Du L, Poovaiah B. A calcium/calmodulin-regulated member of the receptor-like kinase family confers cold tolerance in plants. J Biol Chem. 2010;285:7119-26 pubmed publisher
    ..Northern analysis showed that the induction of cold-responsive genes, including CBF1, RD29A, COR15a, and KIN1 in crlk1 mutants, is delayed as compared with wild-type plants...
  7. Dodd A, Jakobsen M, Baker A, Telzerow A, Hou S, Laplaze L, et al. Time of day modulates low-temperature Ca signals in Arabidopsis. Plant J. 2006;48:962-73 pubmed
    ..calcium ([Ca(2+)](cyt)), and regulation of [Ca(2+)](cyt)-dependent outputs of the LT-signalling network (RD29A transcript abundance and stomatal closure)...
  8. Nakashima K, Fujita Y, Katsura K, Maruyama K, Narusaka Y, Seki M, et al. Transcriptional regulation of ABI3- and ABA-responsive genes including RD29B and RD29A in seeds, germinating embryos, and seedlings of Arabidopsis. Plant Mol Biol. 2006;60:51-68 pubmed
    ..Dehydration-responsive elements (DREs) function as coupling elements of ABRE in the expression of RD29A in response to ABA...
  9. Zhang L, Li Z, Quan R, Li G, Wang R, Huang R. An AP2 domain-containing gene, ESE1, targeted by the ethylene signaling component EIN3 is important for the salt response in Arabidopsis. Plant Physiol. 2011;157:854-65 pubmed publisher
    ..ESE1 in turn binds to promoters of salt-related genes, such as RD29A and COR15A...
  10. Modarresi M, Eyvazi A. Bioinformatical evaluation of desiccation-responsive rd29A gene in Arabidopsis thaliana. Pak J Biol Sci. 2014;17:80-5 pubmed
    ..These two genes called, rd29A and rd29B are located in 8-9 Kb of Arabidopsis genome...
  11. Yang T, Shad Ali G, Yang L, Du L, Reddy A, Poovaiah B. Calcium/calmodulin-regulated receptor-like kinase CRLK1 interacts with MEKK1 in plants. Plant Signal Behav. 2010;5:991-4 pubmed publisher
    ..These results suggest that calcium/calmodulin-regulated CRLK1 modulates cold acclimation through MAP kinase cascade in plants. ..
  12. Xiong L, Ishitani M, Zhu J. Interaction of osmotic stress, temperature, and abscisic acid in the regulation of gene expression in Arabidopsis. Plant Physiol. 1999;119:205-12 pubmed
    ..By using a transgene (RD29A-LUC) consisting of the firefly luciferase coding sequence (LUC) driven by the stress-responsive RD29A promoter, we ..
  13. Liu X, Zhu Y, Zhai H, Cai H, Ji W, Luo X, et al. AtPP2CG1, a protein phosphatase 2C, positively regulates salt tolerance of Arabidopsis in abscisic acid-dependent manner. Biochem Biophys Res Commun. 2012;422:710-5 pubmed publisher
    ..Under salt treatment, AtPP2CG1 up-regulated the expression levels of stress-responsive genes, including RD29A, RD29B, DREB2A and KIN1...
  14. Hu Y, Chen L, Wang H, Zhang L, Wang F, Yu D. Arabidopsis transcription factor WRKY8 functions antagonistically with its interacting partner VQ9 to modulate salinity stress tolerance. Plant J. 2013;74:730-45 pubmed publisher
    ..Moreover, chromatin immunoprecipitation (ChIP) assays showed that WRKY8 directly bound the promoter of RD29A under salt conditions...
  15. Yamaguchi Shinozaki K, Shinozaki K. A novel cis-acting element in an Arabidopsis gene is involved in responsiveness to drought, low-temperature, or high-salt stress. Plant Cell. 1994;6:251-64 pubmed
    Two genes, rd29A and rd29B, which are closely located on the Arabidopsis genome, are differentially induced under conditions of dehydration, low temperature, high salt, or treatment with exogenous abscisic acid (ABA)...
  16. Kaye Y, Golani Y, Singer Y, Leshem Y, Cohen G, Ercetin M, et al. Inositol polyphosphate 5-phosphatase7 regulates the production of reactive oxygen species and salt tolerance in Arabidopsis. Plant Physiol. 2011;157:229-41 pubmed publisher
    ..Analysis of salt-responsive gene expression showed that mutants failed to induce the RD29A and RD22 genes, which contain several ROS-dependent elements in their promoters...
  17. Zalejski C, Paradis S, Maldiney R, Habricot Y, Miginiac E, Rona J, et al. Induction of abscisic acid-regulated gene expression by diacylglycerol pyrophosphate involves Ca2+ and anion currents in Arabidopsis suspension cells. Plant Physiol. 2006;141:1555-62 pubmed
    ..At5g06760, LTI30, RD29A, and RAB18 were stimulated by ABA and also specifically expressed in DGPP-treated cells...
  18. Kim K, Jang Y, Lee S, Oh B, Chae J, Lee K. Alleviation of salt stress by enterobacter sp. EJ01 in tomato and Arabidopsis is accompanied by up-regulation of conserved salinity responsive factors in plants. Mol Cells. 2014;37:109-17 pubmed publisher
    ..level, short-term treatment with EJ01 increased the expression of salt stress responsive genes such as DREB2b, RD29A, RD29B, and RAB18 in Arabidopsis. The expression of proline biosynthetic genes (i.e...
  19. Horvath D, McLarney B, Thomashow M. Regulation of Arabidopsis thaliana L. (Heyn) cor78 in response to low temperature. Plant Physiol. 1993;103:1047-53 pubmed
    ..Heyn). Here we examine the cold-regulated expression of A. thaliana cor78. The results of gene-fusion experiments confirm the finding of Yamaguchi-Shinozaki and Shinozaki ([1993] Mol Gen ..
  20. Behnam B, Kikuchi A, Celebi Toprak F, Kasuga M, Yamaguchi Shinozaki K, Watanabe K. Arabidopsis rd29A::DREB1A enhances freezing tolerance in transgenic potato. Plant Cell Rep. 2007;26:1275-82 pubmed
    ..The lines were transgenic for the DREB1A gene under control of the rd29A promoter, both of which were derived from Arabidopsis thaliana...
  21. Yamaguchi Shinozaki K, Shinozaki K. The plant hormone abscisic acid mediates the drought-induced expression but not the seed-specific expression of rd22, a gene responsive to dehydration stress in Arabidopsis thaliana. Mol Gen Genet. 1993;238:17-25 pubmed
    ..thaliana genome, while the gene for USP from V. faba is actually a family of genes with 10 to 20 members.(ABSTRACT TRUNCATED AT 250 WORDS) ..