LOX2

Summary

Gene Symbol: LOX2
Description: lipoxygenase 2
Alias: ARABIODOPSIS THALIANA LIPOXYGENASE 2, ATLOX2, lipoxygenase 2, lipoxygenase 2
Species: thale cress
Products:     LOX2

Top Publications

  1. Bell E, Mullet J. Characterization of an Arabidopsis lipoxygenase gene responsive to methyl jasmonate and wounding. Plant Physiol. 1993;103:1133-7 pubmed
    A cDNA corresponding to the gene AtLox2 was isolated from an Arabidopsis thaliana library using a lipoxygenase (LOX) probe from soybean...
  2. Bannenberg G, Martínez M, Hamberg M, Castresana C. Diversity of the enzymatic activity in the lipoxygenase gene family of Arabidopsis thaliana. Lipids. 2009;44:85-95 pubmed publisher
    ..None of the enzymes had dual positional specificity. The determined activities correlated with that predicted by their phylogenetic relationship to other biochemically-characterized plant lipoxygenases. ..
  3. Mochizuki S, Sugimoto K, Koeduka T, Matsui K. Arabidopsis lipoxygenase 2 is essential for formation of green leaf volatiles and five-carbon volatiles. FEBS Lett. 2016;590:1017-27 pubmed publisher
    ..Here we identify a lipoxygenase 2 (LOX2) involved in GLV biosynthesis in Arabidopsis using mutant lines for each of the six LOX isoforms present ..
  4. Freire M, Tourneur C, Granier F, Camonis J, El Amrani A, Browning K, et al. Plant lipoxygenase 2 is a translation initiation factor-4E-binding protein. Plant Mol Biol. 2000;44:129-40 pubmed
    ..thaliana using the yeast genetic interaction system identified a clone encoding a lipoxygenase type 2 (AtLOX2). In vitro and in vivo biochemical assays confirm an interaction between AtLOX2 and plant eIF4E(iso) factor...
  5. Jakob K, Kniskern J, Bergelson J. The role of pectate lyase and the jasmonic acid defense response in Pseudomonas viridiflava virulence. Mol Plant Microbe Interact. 2007;20:146-58 pubmed
    ..thaliana to several strains of P. viridiflava collected from this host by quantifying the expression of PR-1 and LOX2/PDF1.2, which serve as markers for induction of the salicylic and jasmonic acid (JA) pathways, respectively...
  6. Weech M, Chapleau M, Pan L, Ide C, Bede J. Caterpillar saliva interferes with induced Arabidopsis thaliana defence responses via the systemic acquired resistance pathway. J Exp Bot. 2008;59:2437-48 pubmed publisher
    ..This salivary-specific difference in jasmonic acid levels was alleviated in SAR(-) mutants. These results support the model that caterpillar saliva interferes with jasmonate-dependent plant defences by activating the SAR pathway. ..
  7. Kilaru A, Herrfurth C, Keereetaweep J, Hornung E, Venables B, Feussner I, et al. Lipoxygenase-mediated oxidation of polyunsaturated N-acylethanolamines in Arabidopsis. J Biol Chem. 2011;286:15205-14 pubmed publisher
    ..Escherichia coli utilized NAE 18:2 and NAE 18:3 as substrates with AtLOX1 and AtLOX5 exhibiting 9-LOX activity and AtLOX2, AtLOX3, AtLOX4, and AtLOX6 showing predominantly 13-LOX activity...
  8. Bell E, Creelman R, Mullet J. A chloroplast lipoxygenase is required for wound-induced jasmonic acid accumulation in Arabidopsis. Proc Natl Acad Sci U S A. 1995;92:8675-9 pubmed
    ..The potential involvement of a specific Arabidopsis thaliana lipoxygenase isozyme, LOX2, in the biosynthesis of the plant growth regulators jasmonic acid (JA) and abscisic acid was investigated...
  9. Zhao Y, Zhou J, Xing D. Phytochrome B-mediated activation of lipoxygenase modulates an excess red light-induced defence response in Arabidopsis. J Exp Bot. 2014;65:4907-18 pubmed publisher
    ..In conditions of RL-induced defence, Arabidopsis LOX activity and transcription levels of LOX2, LOX3, and LOX4 were both upregulated...
  10. Ren C, Pan J, Peng W, Genschik P, Hobbie L, Hellmann H, et al. Point mutations in Arabidopsis Cullin1 reveal its essential role in jasmonate response. Plant J. 2005;42:514-24 pubmed
    ..Furthermore, we show that the point mutations in AtCUL1 affect the assembly of COI1 into SCF, thus attenuating SCF(COI1) formation. ..

Detail Information

Publications12

  1. Bell E, Mullet J. Characterization of an Arabidopsis lipoxygenase gene responsive to methyl jasmonate and wounding. Plant Physiol. 1993;103:1133-7 pubmed
    A cDNA corresponding to the gene AtLox2 was isolated from an Arabidopsis thaliana library using a lipoxygenase (LOX) probe from soybean...
  2. Bannenberg G, Martínez M, Hamberg M, Castresana C. Diversity of the enzymatic activity in the lipoxygenase gene family of Arabidopsis thaliana. Lipids. 2009;44:85-95 pubmed publisher
    ..None of the enzymes had dual positional specificity. The determined activities correlated with that predicted by their phylogenetic relationship to other biochemically-characterized plant lipoxygenases. ..
  3. Mochizuki S, Sugimoto K, Koeduka T, Matsui K. Arabidopsis lipoxygenase 2 is essential for formation of green leaf volatiles and five-carbon volatiles. FEBS Lett. 2016;590:1017-27 pubmed publisher
    ..Here we identify a lipoxygenase 2 (LOX2) involved in GLV biosynthesis in Arabidopsis using mutant lines for each of the six LOX isoforms present ..
  4. Freire M, Tourneur C, Granier F, Camonis J, El Amrani A, Browning K, et al. Plant lipoxygenase 2 is a translation initiation factor-4E-binding protein. Plant Mol Biol. 2000;44:129-40 pubmed
    ..thaliana using the yeast genetic interaction system identified a clone encoding a lipoxygenase type 2 (AtLOX2). In vitro and in vivo biochemical assays confirm an interaction between AtLOX2 and plant eIF4E(iso) factor...
  5. Jakob K, Kniskern J, Bergelson J. The role of pectate lyase and the jasmonic acid defense response in Pseudomonas viridiflava virulence. Mol Plant Microbe Interact. 2007;20:146-58 pubmed
    ..thaliana to several strains of P. viridiflava collected from this host by quantifying the expression of PR-1 and LOX2/PDF1.2, which serve as markers for induction of the salicylic and jasmonic acid (JA) pathways, respectively...
  6. Weech M, Chapleau M, Pan L, Ide C, Bede J. Caterpillar saliva interferes with induced Arabidopsis thaliana defence responses via the systemic acquired resistance pathway. J Exp Bot. 2008;59:2437-48 pubmed publisher
    ..This salivary-specific difference in jasmonic acid levels was alleviated in SAR(-) mutants. These results support the model that caterpillar saliva interferes with jasmonate-dependent plant defences by activating the SAR pathway. ..
  7. Kilaru A, Herrfurth C, Keereetaweep J, Hornung E, Venables B, Feussner I, et al. Lipoxygenase-mediated oxidation of polyunsaturated N-acylethanolamines in Arabidopsis. J Biol Chem. 2011;286:15205-14 pubmed publisher
    ..Escherichia coli utilized NAE 18:2 and NAE 18:3 as substrates with AtLOX1 and AtLOX5 exhibiting 9-LOX activity and AtLOX2, AtLOX3, AtLOX4, and AtLOX6 showing predominantly 13-LOX activity...
  8. Bell E, Creelman R, Mullet J. A chloroplast lipoxygenase is required for wound-induced jasmonic acid accumulation in Arabidopsis. Proc Natl Acad Sci U S A. 1995;92:8675-9 pubmed
    ..The potential involvement of a specific Arabidopsis thaliana lipoxygenase isozyme, LOX2, in the biosynthesis of the plant growth regulators jasmonic acid (JA) and abscisic acid was investigated...
  9. Zhao Y, Zhou J, Xing D. Phytochrome B-mediated activation of lipoxygenase modulates an excess red light-induced defence response in Arabidopsis. J Exp Bot. 2014;65:4907-18 pubmed publisher
    ..In conditions of RL-induced defence, Arabidopsis LOX activity and transcription levels of LOX2, LOX3, and LOX4 were both upregulated...
  10. Ren C, Pan J, Peng W, Genschik P, Hobbie L, Hellmann H, et al. Point mutations in Arabidopsis Cullin1 reveal its essential role in jasmonate response. Plant J. 2005;42:514-24 pubmed
    ..Furthermore, we show that the point mutations in AtCUL1 affect the assembly of COI1 into SCF, thus attenuating SCF(COI1) formation. ..
  11. Moran P, Thompson G. Molecular responses to aphid feeding in Arabidopsis in relation to plant defense pathways. Plant Physiol. 2001;125:1074-85 pubmed
    ..Transcripts encoding JA-inducible lipoxygenase (LOX2) and SA/JA-inducible Phe-ammonia lyase increased 1.5- to 2-fold. PDF1...
  12. Thatcher L, Manners J, Kazan K. Fusarium oxysporum hijacks COI1-mediated jasmonate signaling to promote disease development in Arabidopsis. Plant J. 2009;58:927-39 pubmed publisher
    ..Together, our results indicate that F. oxysporum hijacks non-defensive aspects of the JA-signaling pathway to cause wilt-disease symptoms that lead to plant death in Arabidopsis. ..