Gene Symbol: LKP2
Description: LOV KELCH protein 2
Alias: ADAGIO 2, ADO2, LOV KELCH protein 2, LOV KELCH protein 2
Species: thale cress
Fukamatsu Y, Mitsui S, Yasuhara M, Tokioka Y, Ihara N, Fujita S, et al
. Identification of LOV KELCH PROTEIN2 (LKP2)-interacting factors that can recruit LKP2 to nuclear bodies. Plant Cell Physiol. 2005;46:1340-9 pubmed
LOV KELCH PROTEIN2 (LKP2) is an F-box protein that has been postulated to function centrally, or near to the circadian clock oscillator...
Kim W, Fujiwara S, Suh S, Kim J, Kim Y, Han L, et al
. ZEITLUPE is a circadian photoreceptor stabilized by GIGANTEA in blue light. Nature. 2007;449:356-60 pubmed
..This mechanism of establishing and sustaining robust oscillations of ZTL results in the high-amplitude TOC1 rhythms necessary for proper clock function. ..
Baudry A, Ito S, Song Y, Strait A, Kiba T, Lu S, et al
. F-box proteins FKF1 and LKP2 act in concert with ZEITLUPE to control Arabidopsis clock progression. Plant Cell. 2010;22:606-22 pubmed publisher
..Here, we report that FLAVIN BINDING, KELCH REPEAT, F-BOX1 (FKF1) and LOV KELCH PROTEIN2 (LKP2) play similar roles to ZTL in the circadian clock when ZTL is absent...
Liu H, Wang Q, Liu Y, Zhao X, Imaizumi T, Somers D, et al
. Arabidopsis CRY2 and ZTL mediate blue-light regulation of the transcription factor CIB1 by distinct mechanisms. Proc Natl Acad Sci U S A. 2013;110:17582-7 pubmed publisher
..Instead, two of the three light-oxygen-voltage (LOV)-domain photoreceptors, ZEITLUPE and LOV KELCH PROTEIN 2, but not FLAVIN-BINDING KELCH REPEAT 1, are required for the function and blue-light suppression of ..
Jarillo J, Capel J, Tang R, Yang H, Alonso J, Ecker J, et al
. An Arabidopsis circadian clock component interacts with both CRY1 and phyB. Nature. 2001;410:487-90 pubmed
..Both yeast two-hybrid and in vitro binding studies show that there is a physical interaction between ADO1 and the photoreceptors CRY1 and phyB. We propose that ADO1 is an important component of the Arabidopsis circadian system. ..
Schultz T, Kiyosue T, Yanovsky M, Wada M, Kay S. A role for LKP2 in the circadian clock of Arabidopsis. Plant Cell. 2001;13:2659-70 pubmed
A third member of the ZTL gene family was identified in the Arabidopsis genome and was named LKP2 (for LOV kelch protein2). A cDNA was isolated corresponding to this gene, and plants overexpressing LKP2 were generated...
Mas P, Kim W, Somers D, Kay S. Targeted degradation of TOC1 by ZTL modulates circadian function in Arabidopsis thaliana. Nature. 2003;426:567-70 pubmed
..Our results show that the TOC1-ZTL interaction is important in the control of TOC1 protein stability, and is probably responsible for the regulation of circadian period by the clock. ..
Takase T, Nishiyama Y, Tanihigashi H, Ogura Y, Miyazaki Y, Yamada Y, et al
. LOV KELCH PROTEIN2 and ZEITLUPE repress Arabidopsis photoperiodic flowering under non-inductive conditions, dependent on FLAVIN-BINDING KELCH REPEAT F-BOX1. Plant J. 2011;67:608-21 pubmed publisher
LOV KELCH PROTEIN2 (LKP2), ZEITLUPE (ZTL)/LOV KELCH PROTEIN1 (LKP1) and FLAVIN-BINDING KELCH REPEAT F-BOX1 (FKF1) constitute a family of Arabidopsis F-box proteins that regulate the circadian clock...
Yasuhara M, Mitsui S, Hirano H, Takanabe R, Tokioka Y, Ihara N, et al
. Identification of ASK and clock-associated proteins as molecular partners of LKP2 (LOV kelch protein 2) in Arabidopsis. J Exp Bot. 2004;55:2015-27 pubmed
..have a LOV domain, an F-box motif, and a kelch repeat region. LKP2 is a member of this family and functions either within or very close to the circadian oscillator in Arabidopsis...