Gene Symbol: IVD
Description: isovaleryl-CoA-dehydrogenase
Species: thale cress

Top Publications

  1. Däschner K, Couée I, Binder S. The mitochondrial isovaleryl-coenzyme a dehydrogenase of arabidopsis oxidizes intermediates of leucine and valine catabolism. Plant Physiol. 2001;126:601-12 pubmed
    We recently identified a cDNA encoding a putative isovaleryl-coenzyme A (CoA) dehydrogenase in Arabidopsis (AtIVD)...
  2. Gu L, Jones A, Last R. Broad connections in the Arabidopsis seed metabolic network revealed by metabolite profiling of an amino acid catabolism mutant. Plant J. 2010;61:579-90 pubmed publisher
    ..of impaired branched chain amino acid catabolic enzyme isovaleryl-CoA dehydrogenase (encoded by gene At3g45300 or atIVD) as the cause of this metabolic syndrome...
  3. Däschner K, Thalheim C, Guha C, Brennicke A, Binder S. In plants a putative isovaleryl-CoA-dehydrogenase is located in mitochondria. Plant Mol Biol. 1999;39:1275-82 pubmed
    ..protein and corresponding cDNA for an enzyme of the leucine catabolic pathway, the isovaleryl-CoA-dehydrogenase (IVD)...
  4. Taylor N, Heazlewood J, Day D, Millar A. Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis. Plant Physiol. 2004;134:838-48 pubmed
    ..The potential role of branched-chain amino acid catabolism as an oxidative phosphorylation energy source or as a detoxification pathway during plant stress is discussed. ..
  5. Araujo W, Ishizaki K, Nunes Nesi A, Larson T, Tohge T, Krahnert I, et al. Identification of the 2-hydroxyglutarate and isovaleryl-CoA dehydrogenases as alternative electron donors linking lysine catabolism to the electron transport chain of Arabidopsis mitochondria. Plant Cell. 2010;22:1549-63 pubmed publisher