Gene Symbol: IAA19
Description: indole-3-acetic acid inducible 19
Alias: MASSUGU 2, MJK13.22, MSG2, indole-3-acetic acid inducible 19, indole-3-acetic acid inducible 19
Species: thale cress
Products:     IAA19

Top Publications

  1. Tashiro S, Tian C, Watahiki M, Yamamoto K. Changes in growth kinetics of stamen filaments cause inefficient pollination in massugu2, an auxin insensitive, dominant mutant of Arabidopsis thaliana. Physiol Plant. 2009;137:175-87 pubmed publisher
    ..basis of lower fecundity of massugu2 (msg2), which is a dominant mutant of an auxin primary response gene, IAA19, in Arabidopsis thaliana...
  2. Tatematsu K, Kumagai S, Muto H, Sato A, Watahiki M, Harper R, et al. MASSUGU2 encodes Aux/IAA19, an auxin-regulated protein that functions together with the transcriptional activator NPH4/ARF7 to regulate differential growth responses of hypocotyl and formation of lateral roots in Arabidopsis thaliana. Plant Cell. 2004;16:379-93 pubmed
    ..alleles result in amino acid substitutions in the conserved domain II of an Auxin/Indole-3-Acetic Acid protein, IAA19. Interestingly, auxin inducibility of MSG2/IAA19 gene expression is reduced by 65% in nph4/arf7...
  3. Muto H, Nagao I, Demura T, Fukuda H, Kinjo M, Yamamoto K. Fluorescence cross-correlation analyses of the molecular interaction between an Aux/IAA protein, MSG2/IAA19, and protein-protein interaction domains of auxin response factors of arabidopsis expressed in HeLa cells. Plant Cell Physiol. 2006;47:1095-101 pubmed
    ..the C-terminal protein-protein interaction domains (CTDs) of Arabidopsis ARFs, MP/ARF5 and NPH4/ARF7, and MSG2/IAA19, fused to fluorescent proteins in HeLa cells, and determined their molecular interactions with fluorescence cross-..
  4. Muto H, Watahiki M, Nakamoto D, Kinjo M, Yamamoto K. Specificity and similarity of functions of the Aux/IAA genes in auxin signaling of Arabidopsis revealed by promoter-exchange experiments among MSG2/IAA19, AXR2/IAA7, and SLR/IAA14. Plant Physiol. 2007;144:187-96 pubmed
    ..function, we examined phenotypes of transgenic plants expressing the green fluorescent protein (GFP)-tagged msg2-1/iaa19, axr2-1/iaa7, or slr-1/iaa14 cDNA by the MSG2 or AXR2 promoter...
  5. Liscum E, Reed J. Genetics of Aux/IAA and ARF action in plant growth and development. Plant Mol Biol. 2002;49:387-400 pubmed
    ..We will also discuss potential mechanisms for interactions between auxin and light response pathways that are suggested by these mutants. ..
  6. Zhou X, Song L, Xue H. Brassinosteroids regulate the differential growth of Arabidopsis hypocotyls through auxin signaling components IAA19 and ARF7. Mol Plant. 2013;6:887-904 pubmed publisher
    ..hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of ..
  7. Shin R, Burch A, Huppert K, Tiwari S, Murphy A, Guilfoyle T, et al. The Arabidopsis transcription factor MYB77 modulates auxin signal transduction. Plant Cell. 2007;19:2440-53 pubmed
    ..This newly defined transcription factor interaction is part of the plant cells' repertoire for modulating response to auxin, thereby controlling lateral root growth and development under changing environmental conditions. ..
  8. Trevisan S, Pizzeghello D, Ruperti B, Francioso O, Sassi A, Palme K, et al. Humic substances induce lateral root formation and expression of the early auxin-responsive IAA19 gene and DR5 synthetic element in Arabidopsis. Plant Biol (Stuttg). 2010;12:604-14 pubmed publisher
    ..These findings were further supported by the fact that HS used in this study activated the auxin synthetic reporter DR5::GUS and enhanced transcription of the early auxin responsive gene IAA19.
  9. Li J, Bush J, Xiong Y, Li L, McCormack M. Large-scale protein-protein interaction analysis in Arabidopsis mesophyll protoplasts by split firefly luciferase complementation. PLoS ONE. 2011;6:e27364 pubmed publisher
    ..Our results demonstrated that the SFLC assay is ideal for in vivo quantitative PPI analysis in plant cells and is particularly powerful for large-scale binary PPI screens...

More Information


  1. Cho H, Ryu H, Rho S, Hill K, Smith S, Audenaert D, et al. A secreted peptide acts on BIN2-mediated phosphorylation of ARFs to potentiate auxin response during lateral root development. Nat Cell Biol. 2014;16:66-76 pubmed publisher
    ..In summary, this study delineates a TDIF-TDR-BIN2 signalling cascade that controls regulation of ARF and AUX/IAA interaction independent of auxin perception during lateral root development...
  2. Kim J, Harter K, Theologis A. Protein-protein interactions among the Aux/IAA proteins. Proc Natl Acad Sci U S A. 1997;94:11786-91 pubmed
    ..These interactions provide a molecular basis for the developmental and tissue-specific manner of auxin action. ..
  3. Sun J, Qi L, Li Y, Zhai Q, Li C. PIF4 and PIF5 transcription factors link blue light and auxin to regulate the phototropic response in Arabidopsis. Plant Cell. 2013;25:2102-14 pubmed publisher
    ..we demonstrate that PIF4 directly activates the expression of the auxin/indole-3-acetic acid (IAA) genes IAA19 and IAA29 by binding to the G-box (CACGTG) motifs in their promoters...