Gene Symbol: HXK2
Description: hexokinase 2
Alias: ARABIDOPSIS THALIANA HEXOKINASE 2, ATHXK2, F6F22.11, F6F22_11, HEXOKINASE 2, hexokinase 2, hexokinase 2
Species: thale cress
Karve A, Rauh B, Xia X, Kandasamy M, Meagher R, Sheen J, et al
. Expression and evolutionary features of the hexokinase gene family in Arabidopsis. Planta. 2008;228:411-25 pubmed publisher
..We further discuss the possibility that the non-catalytic HKL proteins have regulatory functions instead of catalytic functions. ..
Kim M, Lim J, Ahn C, Park K, Kim G, Kim W, et al
. Mitochondria-associated hexokinases play a role in the control of programmed cell death in Nicotiana benthamiana. Plant Cell. 2006;18:2341-55 pubmed
..Furthermore, based on flow cytometry, Arabidopsis thaliana plants overexpressing Arabidopsis HXK1 and HXK2, both of which are predominantly associated with mitochondria, exhibited enhanced resistance to H(2)O(2)- and alpha-..
Jang J, Leon P, Zhou L, Sheen J. Hexokinase as a sugar sensor in higher plants. Plant Cell. 1997;9:5-19 pubmed
..The result suggests that HXK is a dual-function enzyme with a distinct regulatory function not interchangeable between plants and yeast. ..
Eastmond P, van Dijken A, Spielman M, Kerr A, Tissier A, Dickinson H, et al
. Trehalose-6-phosphate synthase 1, which catalyses the first step in trehalose synthesis, is essential for Arabidopsis embryo maturation. Plant J. 2002;29:225-35 pubmed
..However, T-6-P is not an inhibitor of AtHXK1 or AtHXK2. Nor does reducing hexokinase activity rescue tps1-1 embryo growth...
Giegé P, Heazlewood J, Roessner Tunali U, Millar A, Fernie A, Leaver C, et al
. Enzymes of glycolysis are functionally associated with the mitochondrion in Arabidopsis cells. Plant Cell. 2003;15:2140-51 pubmed
Duncan O, Taylor N, Carrie C, Eubel H, Kubiszewski Jakubiak S, Zhang B, et al
. Multiple lines of evidence localize signaling, morphology, and lipid biosynthesis machinery to the mitochondrial outer membrane of Arabidopsis. Plant Physiol. 2011;157:1093-113 pubmed publisher