Gene Symbol: HXK2
Description: hexokinase 2
Alias: ARABIDOPSIS THALIANA HEXOKINASE 2, ATHXK2, F6F22.11, F6F22_11, HEXOKINASE 2, hexokinase 2, hexokinase 2
Species: thale cress

Top Publications

  1. Karve A, Rauh B, Xia X, Kandasamy M, Meagher R, Sheen J, et al. Expression and evolutionary features of the hexokinase gene family in Arabidopsis. Planta. 2008;228:411-25 pubmed publisher
    ..We further discuss the possibility that the non-catalytic HKL proteins have regulatory functions instead of catalytic functions. ..
  2. Kim M, Lim J, Ahn C, Park K, Kim G, Kim W, et al. Mitochondria-associated hexokinases play a role in the control of programmed cell death in Nicotiana benthamiana. Plant Cell. 2006;18:2341-55 pubmed
    ..Furthermore, based on flow cytometry, Arabidopsis thaliana plants overexpressing Arabidopsis HXK1 and HXK2, both of which are predominantly associated with mitochondria, exhibited enhanced resistance to H(2)O(2)- and alpha-..
  3. Jang J, Leon P, Zhou L, Sheen J. Hexokinase as a sugar sensor in higher plants. Plant Cell. 1997;9:5-19 pubmed
    ..The result suggests that HXK is a dual-function enzyme with a distinct regulatory function not interchangeable between plants and yeast. ..
  4. Eastmond P, van Dijken A, Spielman M, Kerr A, Tissier A, Dickinson H, et al. Trehalose-6-phosphate synthase 1, which catalyses the first step in trehalose synthesis, is essential for Arabidopsis embryo maturation. Plant J. 2002;29:225-35 pubmed
    ..However, T-6-P is not an inhibitor of AtHXK1 or AtHXK2. Nor does reducing hexokinase activity rescue tps1-1 embryo growth...
  5. Giegé P, Heazlewood J, Roessner Tunali U, Millar A, Fernie A, Leaver C, et al. Enzymes of glycolysis are functionally associated with the mitochondrion in Arabidopsis cells. Plant Cell. 2003;15:2140-51 pubmed
  6. Duncan O, Taylor N, Carrie C, Eubel H, Kubiszewski Jakubiak S, Zhang B, et al. Multiple lines of evidence localize signaling, morphology, and lipid biosynthesis machinery to the mitochondrial outer membrane of Arabidopsis. Plant Physiol. 2011;157:1093-113 pubmed publisher