Gene Symbol: Hsp70-2
Description: Heat shock protein 70 (Hsp 70) family protein
Alias: AtHsp70-2, T22P11.80, T22P11_80, Heat shock protein 70 (Hsp 70) family protein
Species: thale cress

Top Publications

  1. Sung D, Vierling E, Guy C. Comprehensive expression profile analysis of the Arabidopsis Hsp70 gene family. Plant Physiol. 2001;126:789-800 pubmed
  2. Kriechbaumer V, Tsargorodskaya A, Mustafa M, Vinogradova T, Lacey J, Smith D, et al. Study of receptor-chaperone interactions using the optical technique of spectroscopic ellipsometry. Biophys J. 2011;101:504-11 pubmed publisher
  3. Gou M, Zhang Z, Zhang N, Huang Q, Monaghan J, Yang H, et al. Opposing Effects on Two Phases of Defense Responses from Concerted Actions of HEAT SHOCK COGNATE70 and BONZAI1 in Arabidopsis. Plant Physiol. 2015;169:2304-23 pubmed publisher
  4. Aparicio F, Thomas C, Lederer C, Niu Y, Wang D, Maule A. Virus induction of heat shock protein 70 reflects a general response to protein accumulation in the plant cytosol. Plant Physiol. 2005;138:529-36 pubmed
    ..This phenomenon is reminiscent of the unfolded protein response observed when the induced accumulation of proteins in the endoplasmic reticulum also induces a specific suite of chaperones. ..
  5. Noël L, Cagna G, Stuttmann J, Wirthmüller L, Betsuyaku S, Witte C, et al. Interaction between SGT1 and cytosolic/nuclear HSC70 chaperones regulates Arabidopsis immune responses. Plant Cell. 2007;19:4061-76 pubmed
    ..We conclude that an HSC70-SGT1 chaperone complex is important for multiple plant environmental responses and that the evolutionarily conserved SGS domain of SGT1 is a key determinant of the HSC70-SGT1 association. ..
  6. Brkljacic J, Zhao Q, Meier I. WPP-domain proteins mimic the activity of the HSC70-1 chaperone in preventing mistargeting of RanGAP1-anchoring protein WIT1. Plant Physiol. 2009;151:142-54 pubmed publisher
    ..Taken together, our data suggest that both HSC70-1 and the WPP-domain proteins play a role in facilitating WIT1 nuclear envelope targeting, which is, to our knowledge, the first described in planta activity for the WPP-domain proteins. ..
  7. Jungkunz I, Link K, Vogel F, Voll L, Sonnewald S, Sonnewald U. AtHsp70-15-deficient Arabidopsis plants are characterized by reduced growth, a constitutive cytosolic protein response and enhanced resistance to TuMV. Plant J. 2011;66:983-95 pubmed publisher
    ..Based on these results, AtHsp70-15 is likely to be a key factor in proper folding of cytosolic proteins, and may function as nucleotide exchange factor as proposed for yeast. ..