Gene Symbol: Hsp70-2
Description: Heat shock protein 70 (Hsp 70) family protein
Alias: AtHsp70-2, T22P11.80, T22P11_80, Heat shock protein 70 (Hsp 70) family protein
Species: thale cress
Sung D, Vierling E, Guy C. Comprehensive expression profile analysis of the Arabidopsis Hsp70 gene family. Plant Physiol. 2001;126:789-800 pubmed
Kriechbaumer V, Tsargorodskaya A, Mustafa M, Vinogradova T, Lacey J, Smith D, et al
. Study of receptor-chaperone interactions using the optical technique of spectroscopic ellipsometry. Biophys J. 2011;101:504-11 pubmed publisher
Gou M, Zhang Z, Zhang N, Huang Q, Monaghan J, Yang H, et al
. Opposing Effects on Two Phases of Defense Responses from Concerted Actions of HEAT SHOCK COGNATE70 and BONZAI1 in Arabidopsis. Plant Physiol. 2015;169:2304-23 pubmed publisher
Aparicio F, Thomas C, Lederer C, Niu Y, Wang D, Maule A. Virus induction of heat shock protein 70 reflects a general response to protein accumulation in the plant cytosol. Plant Physiol. 2005;138:529-36 pubmed
..This phenomenon is reminiscent of the unfolded protein response observed when the induced accumulation of proteins in the endoplasmic reticulum also induces a specific suite of chaperones. ..
Noël L, Cagna G, Stuttmann J, Wirthmüller L, Betsuyaku S, Witte C, et al
. Interaction between SGT1 and cytosolic/nuclear HSC70 chaperones regulates Arabidopsis immune responses. Plant Cell. 2007;19:4061-76 pubmed
..We conclude that an HSC70-SGT1 chaperone complex is important for multiple plant environmental responses and that the evolutionarily conserved SGS domain of SGT1 is a key determinant of the HSC70-SGT1 association. ..
Brkljacic J, Zhao Q, Meier I. WPP-domain proteins mimic the activity of the HSC70-1 chaperone in preventing mistargeting of RanGAP1-anchoring protein WIT1. Plant Physiol. 2009;151:142-54 pubmed publisher
..Taken together, our data suggest that both HSC70-1 and the WPP-domain proteins play a role in facilitating WIT1 nuclear envelope targeting, which is, to our knowledge, the first described in planta activity for the WPP-domain proteins. ..
Jungkunz I, Link K, Vogel F, Voll L, Sonnewald S, Sonnewald U. AtHsp70-15-deficient Arabidopsis plants are characterized by reduced growth, a constitutive cytosolic protein response and enhanced resistance to TuMV. Plant J. 2011;66:983-95 pubmed publisher
..Based on these results, AtHsp70-15 is likely to be a key factor in proper folding of cytosolic proteins, and may function as nucleotide exchange factor as proposed for yeast. ..