HSF1

Summary

Gene Symbol: HSF1
Description: heat shock factor 1
Alias: ARABIDOPSIS THALIANA CLASS A HEAT SHOCK FACTOR 1A, ARABIDOPSIS THALIANA HEAT SHOCK FACTOR 1, ATHSF1, ATHSFA1A, CLASS A HEAT SHOCK FACTOR 1A, DL4910C, FCAALL.107, HEAT SHOCK FACTOR, HSFA1A, heat shock factor 1, heat shock factor 1
Species: thale cress

Top Publications

  1. Reindl A, Schöffl F. Interaction between the Arabidopsis thaliana heat shock transcription factor HSF1 and the TATA binding protein TBP. FEBS Lett. 1998;436:318-22 pubmed
    The heat shock factor (HSF1) is the central regulator of the heat stress (hs) response and is required for stimulating the transcription of the hs genes and consequently the expression of heat shock proteins...
  2. Hubel A, Schöffl F. Arabidopsis heat shock factor: isolation and characterization of the gene and the recombinant protein. Plant Mol Biol. 1994;26:353-62 pubmed
    We have isolated the Arabidopsis heat shock factor gene Athsf1 as genomic and corresponding cDNA sequences via cross-hybridization with tomato clones...
  3. Li M, Doll J, Weckermann K, Oecking C, Berendzen K, Schöffl F. Detection of in vivo interactions between Arabidopsis class A-HSFs, using a novel BiFC fragment, and identification of novel class B-HSF interacting proteins. Eur J Cell Biol. 2010;89:126-32 pubmed publisher
    ..Genetic and functional analysis suggests that HsfA1a and HsfA1b are central regulators required in the early phase of the heat shock response, which have the capacity ..
  4. Kim B, Schöffl F. Interaction between Arabidopsis heat shock transcription factor 1 and 70 kDa heat shock proteins. J Exp Bot. 2002;53:371-5 pubmed
    ..Here the interaction between HSF and HSP70 is reported using electrophoretic mobility shift and yeast two-hybrid assays. Subdomain mapping indicates an interaction of the activation domain and DNA-binding domain of HSF1 with HSP70.
  5. Reindl A, Schöffl F, Schell J, Koncz C, Bako L. Phosphorylation by a cyclin-dependent kinase modulates DNA binding of the Arabidopsis heat-shock transcription factor HSF1 in vitro. Plant Physiol. 1997;115:93-100 pubmed
    ..identification, and characterization of a protein kinase that phosphorylates the Arabidopsis heat-shock factor AtHSF1 at multiple serine residues...
  6. Liu H, Li G, Chang H, Sun D, Zhou R, Li B. Calmodulin-binding protein phosphatase PP7 is involved in thermotolerance in Arabidopsis. Plant Cell Environ. 2007;30:156-64 pubmed
    ..In addition, we found that AtPP7 interacts with an HS transcription factor (HSF), suggesting a possible role for AtPP7 in regulating the expression of heat shock protein (HSP) genes. ..
  7. Xu X, Song H, Zhou Z, Shi N, Ying Q, Wang H. Functional characterization of AtHsp90.3 in Saccharomyces cerevisiae and Arabidopsis thaliana under heat stress. Biotechnol Lett. 2010;32:979-87 pubmed publisher
    ..3 under heat stress. These results indicate that overexpressing AtHsp90.3 impaired plant tolerance to heat stress and proper homeostasis of Hsp90 was critical for cellular stress response and/or tolerance in plants. ..
  8. Liu H, Gao F, Li G, Han J, Liu D, Sun D, et al. The calmodulin-binding protein kinase 3 is part of heat-shock signal transduction in Arabidopsis thaliana. Plant J. 2008;55:760-73 pubmed publisher
    ..In this study, using a yeast two-hybrid assay, we found that AtCBK3 interacts with AtHSFA1a. Fluorescence resonance energy transfer was used to confirm the interaction between AtCBK3-YFP and AtHSFA1a-CFP...
  9. Li M, Berendzen K, Schöffl F. Promoter specificity and interactions between early and late Arabidopsis heat shock factors. Plant Mol Biol. 2010;73:559-67 pubmed publisher
    The class A heat shock factors HsfA1a and HsfA1b are highly conserved, interacting regulators, responsible for the immediate-early transcription of a subset of heat shock genes in Arabidopsis...

More Information

Publications13

  1. Hsu S, Lai H, Jinn T. Cytosol-localized heat shock factor-binding protein, AtHSBP, functions as a negative regulator of heat shock response by translocation to the nucleus and is required for seed development in Arabidopsis. Plant Physiol. 2010;153:773-84 pubmed publisher
    ..Protoplast two-hybrid assay results confirmed that AtHSBP interacts with itself and with the HSFs, AtHSFA1a, AtHSFA1b, and AtHSFA2. AtHSBP also negatively affected AtHSFA1b DNA-binding capacity in vitro...
  2. Yoshida T, Ohama N, Nakajima J, Kidokoro S, Mizoi J, Nakashima K, et al. Arabidopsis HsfA1 transcription factors function as the main positive regulators in heat shock-responsive gene expression. Mol Genet Genomics. 2011;286:321-32 pubmed publisher
    ..the 21 Arabidopsis heat shock factors, we chose 4 HsfA1-type proteins as candidate transcriptional activators (HsfA1a, HsfA1b, HsfA1d, and HsfA1e) based on transactivation activity and expression patterns...
  3. Qian J, Chen J, Liu Y, Yang L, Li W, Zhang L. Overexpression of Arabidopsis HsfA1a enhances diverse stress tolerance by promoting stress-induced Hsp expression. Genet Mol Res. 2014;13:1233-43 pubmed publisher
    Arabidopsis (Arabidopsis thaliana) group A1 heat shock factors (Hsfs), including HsfA1a, are important regulators in the heat shock response...
  4. Czarnecka Verner E, Pan S, Salem T, Gurley W. Plant class B HSFs inhibit transcription and exhibit affinity for TFIIB and TBP. Plant Mol Biol. 2004;56:57-75 pubmed
    ..In vitro binding studies were consistent with this pattern of activity since the BD region alone interacted strongly with TFIIB, and the presence of RD had an inhibitory effect on TFIIB binding and transcriptional activation. ..