HKT1

Summary

Gene Symbol: HKT1
Description: sodium transporter HKT1
Alias: ATHKT1, T9A4.5, high-affinity K+ transporter 1
Species: thale cress

Top Publications

  1. ncbi Enhanced salt tolerance mediated by AtHKT1 transporter-induced Na unloading from xylem vessels to xylem parenchyma cells
    - Sunarpi
    Bioscience and Biotechnology Center, Nagoya University, Nagoya 464 8601, Japan
    Plant J 44:928-38. 2005
  2. pmc A coastal cline in sodium accumulation in Arabidopsis thaliana is driven by natural variation of the sodium transporter AtHKT1;1
    Ivan Baxter
    United States Department of Agriculture Agricultural Research Service, Plant Genetics Research Unit, Donald Danforth Plant Sciences Center, St Louis, Missouri, United States of America
    PLoS Genet 6:e1001193. 2010
  3. pmc HKT transporter-mediated salinity resistance mechanisms in Arabidopsis and monocot crop plants
    Tomoaki Horie
    Group of Molecular and Functional Plant Biology, Research Institute for Bioresources, Okayama University, Kurashiki, Okayama 710 0046, Japan
    Trends Plant Sci 14:660-8. 2009
  4. pmc AtHKT1 is a salt tolerance determinant that controls Na(+) entry into plant roots
    A Rus
    Center for Plant Environmental Stress Physiology, Purdue University, West Lafayette, IN 47907 1165, USA
    Proc Natl Acad Sci U S A 98:14150-5. 2001
  5. pmc Improved salinity tolerance of rice through cell type-specific expression of AtHKT1;1
    Darren Plett
    Australian Centre for Plant Functional Genomics, University of Adelaide, Glen Osmond, South Australia, Australia
    PLoS ONE 5:e12571. 2010
  6. pmc Functional analysis of AtHKT1 in Arabidopsis shows that Na(+) recirculation by the phloem is crucial for salt tolerance
    Pierre Berthomieu
    Biochimie et Physiologie Moleculaire des Plantes, UMR 5004, ENSA M INRA CNRS UMII and UMR Agronomie Ecophysiologie des Plantes sous Stress Environnementaux, INRA ENSA M, 34060 Montpellier Cedex 2, France
    EMBO J 22:2004-14. 2003
  7. doi Type-B response regulators ARR1 and ARR12 regulate expression of AtHKT1;1 and accumulation of sodium in Arabidopsis shoots
    Michael G Mason
    School of Biological Sciences, University of Queensland, St Lucia, Queensland 4072, Australia
    Plant J 64:753-63. 2010
  8. doi ABI4 downregulates expression of the sodium transporter HKT1;1 in Arabidopsis roots and affects salt tolerance
    Doron Shkolnik-Inbar
    Department of Life Sciences and Doris, Bertie Center for Bioenergetics in Life Sciences, Ben Gurion University of the Negev, Beer Sheva, 84105, Israel
    Plant J 73:993-1005. 2013
  9. pmc AtHKT1;1 mediates nernstian sodium channel transport properties in Arabidopsis root stelar cells
    Shaowu Xue
    Division of Biological Sciences, Cell and Developmental Biology Section, University of California, San Diego, La Jolla, California, United States of America
    PLoS ONE 6:e24725. 2011
  10. pmc Natural variants of AtHKT1 enhance Na+ accumulation in two wild populations of Arabidopsis
    Ana Rus
    Center for Plant Environmental Stress Physiology, Purdue University, West Lafayette, Indiana, United States of America
    PLoS Genet 2:e210. 2006

Scientific Experts

  • N Uozumi
  • Pierre Berthomieu
  • Romola Jane Davenport
  • Tomoaki Horie
  • Michael G Mason
  • Mark Tester
  • Deepa Jha
  • Ana Rus
  • Ivan Baxter
  • Julian I Schroeder
  • Camilla B Hill
  • Doron Shkolnik-Inbar
  • Shaowu Xue
  • Darren Plett
  • Matthew Gilliham
  • Inge S Møller
  • Huiming Zhang
  • Elena Yakubova
  • Brett Lahner
  • David E Salt
  • - Sunarpi
  • Rie Horie
  • Ji Ming Gong
  • Ute Roessner
  • Guy Adler
  • Dudy Bar-Zvi
  • Antony Bacic
  • A Rus
  • Wei Luo
  • Xuan Yao
  • Andrew Jacobs
  • Jessica N Brazelton
  • Neil Shirley
  • Yu S Huang
  • Alexander Johnson
  • Olga Vitek
  • Stuart Roy
  • Justin O Borevitz
  • Inge Skrumsager Møller
  • Gehan Safwat
  • Joy Bergelson
  • Danni Yu
  • Magnus Nordborg
  • Yan Li
  • Juliet C Coates
  • Stuart J Roy
  • Gwenda M Mayo
  • Jim Haseloff
  • Scot E Dowd
  • Huazhong Shi
  • Yan Sun
  • Paul W Pare
  • Mi Seong Kim
  • Jeff Gustin
  • Balasubramaniam Muthukumar
  • Masako Osumi
  • Kazumi Hattori
  • Wai Yin Chan
  • Kinya Yoda
  • Hua Yang
  • Mutsumi Yamagami
  • Masahiro Kubo
  • Jo Motoda
  • Mami Konomi
  • Ho Yin Leung
  • David A Waner
  • Alicia Muñoz-Mayor
  • Shi Lun Li
  • Paul M Hasegawa
  • Kenji Miura
  • Altanbadralt Sharkhuu
  • Khush B Abid
  • Jian Kang Zhu
  • Byeong Ha Lee
  • Ray A Bressan
  • S Yokoi
  • P M Hasegawa
  • T K Matsumoto
  • M Reddy
  • R A Bressan
  • B H Lee
  • J K Zhu
  • H Koiwa
  • A Sharkhuu

Detail Information

Publications18

  1. ncbi Enhanced salt tolerance mediated by AtHKT1 transporter-induced Na unloading from xylem vessels to xylem parenchyma cells
    - Sunarpi
    Bioscience and Biotechnology Center, Nagoya University, Nagoya 464 8601, Japan
    Plant J 44:928-38. 2005
    b>AtHKT1 is a sodium (Na+) transporter that functions in mediating tolerance to salt stress...
  2. pmc A coastal cline in sodium accumulation in Arabidopsis thaliana is driven by natural variation of the sodium transporter AtHKT1;1
    Ivan Baxter
    United States Department of Agriculture Agricultural Research Service, Plant Genetics Research Unit, Donald Danforth Plant Sciences Center, St Louis, Missouri, United States of America
    PLoS Genet 6:e1001193. 2010
    ..complementation, and gene expression studies to identify cis-regulatory expression level polymorphisms at the AtHKT1;1 locus, encoding a known sodium (Na(+)) transporter, as being a major factor controlling natural variation in ..
  3. pmc HKT transporter-mediated salinity resistance mechanisms in Arabidopsis and monocot crop plants
    Tomoaki Horie
    Group of Molecular and Functional Plant Biology, Research Institute for Bioresources, Okayama University, Kurashiki, Okayama 710 0046, Japan
    Trends Plant Sci 14:660-8. 2009
    ..mechanisms mediating salinity resistance have been identified in Arabidopsis , including the AtSOS1, AtNHX and AtHKT1;1 transporters...
  4. pmc AtHKT1 is a salt tolerance determinant that controls Na(+) entry into plant roots
    A Rus
    Center for Plant Environmental Stress Physiology, Purdue University, West Lafayette, IN 47907 1165, USA
    Proc Natl Acad Sci U S A 98:14150-5. 2001
    ..flanking the T-DNA left border indicated that sos3-1 hkt1-1 and sos3-1 hkt1-2 plants have allelic mutations in AtHKT1. AtHKT1 mRNA is more abundant in roots than shoots of wild-type plants but is not detected in plants of either ..
  5. pmc Improved salinity tolerance of rice through cell type-specific expression of AtHKT1;1
    Darren Plett
    Australian Centre for Plant Functional Genomics, University of Adelaide, Glen Osmond, South Australia, Australia
    PLoS ONE 5:e12571. 2010
    Previously, cell type-specific expression of AtHKT1;1, a sodium transporter, improved sodium (Na(+)) exclusion and salinity tolerance in Arabidopsis...
  6. pmc Functional analysis of AtHKT1 in Arabidopsis shows that Na(+) recirculation by the phloem is crucial for salt tolerance
    Pierre Berthomieu
    Biochimie et Physiologie Moleculaire des Plantes, UMR 5004, ENSA M INRA CNRS UMII and UMR Agronomie Ecophysiologie des Plantes sous Stress Environnementaux, INRA ENSA M, 34060 Montpellier Cedex 2, France
    EMBO J 22:2004-14. 2003
    ..The sas2 locus was found (by positional cloning) to correspond to the AtHKT1 gene...
  7. doi Type-B response regulators ARR1 and ARR12 regulate expression of AtHKT1;1 and accumulation of sodium in Arabidopsis shoots
    Michael G Mason
    School of Biological Sciences, University of Queensland, St Lucia, Queensland 4072, Australia
    Plant J 64:753-63. 2010
    ..Expression of the gene encoding Arabidopsis high-affinity K(+) transporter 1;1 (AtHKT1;1), a gene responsible for removing sodium ions from the root xylem, was repressed by cytokinin treatment, but ..
  8. doi ABI4 downregulates expression of the sodium transporter HKT1;1 in Arabidopsis roots and affects salt tolerance
    Doron Shkolnik-Inbar
    Department of Life Sciences and Doris, Bertie Center for Bioenergetics in Life Sciences, Ben Gurion University of the Negev, Beer Sheva, 84105, Israel
    Plant J 73:993-1005. 2013
    ..We show higher HKT1;1 expression in abi4 mutant plants and lower levels of expression in ABI4-overexpressing plants, resulting in ..
  9. pmc AtHKT1;1 mediates nernstian sodium channel transport properties in Arabidopsis root stelar cells
    Shaowu Xue
    Division of Biological Sciences, Cell and Developmental Biology Section, University of California, San Diego, La Jolla, California, United States of America
    PLoS ONE 6:e24725. 2011
    The Arabidopsis AtHKT1;1 protein was identified as a sodium (Na⁺) transporter by heterologous expression in Xenopus laevis oocytes and Saccharomyces cerevisiae...
  10. pmc Natural variants of AtHKT1 enhance Na+ accumulation in two wild populations of Arabidopsis
    Ana Rus
    Center for Plant Environmental Stress Physiology, Purdue University, West Lafayette, Indiana, United States of America
    PLoS Genet 2:e210. 2006
    ..We identify AtHKT1, known to encode a Na(+) transporter, as being the causal locus driving elevated shoot Na(+) in both Ts-1 and Tsu-..
  11. pmc Shoot Na+ exclusion and increased salinity tolerance engineered by cell type-specific alteration of Na+ transport in Arabidopsis
    Inge S Møller
    Department of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom
    Plant Cell 21:2163-78. 2009
    ..Here, it is shown that expression of the Na+ transporter HKT1;1 in the mature root stele of Arabidopsis thaliana decreases Na+ accumulation in the shoot by 37 to 64%...
  12. pmc The Arabidopsis HKT1 gene homolog mediates inward Na(+) currents in xenopus laevis oocytes and Na(+) uptake in Saccharomyces cerevisiae
    N Uozumi
    BioScience Center, Nagoya University, Nagoya, 464 8601, Japan
    Plant Physiol 122:1249-59. 2000
    ..We report here the isolation of a cDNA homologous to HKT1 from Arabidopsis (AtHKT1) and the characterization of its mode of ion transport in heterologous systems...
  13. ncbi Calcium regulation of sodium hypersensitivities of sos3 and athkt1 mutants
    Tomoaki Horie
    Division of Biological Sciences, Cell and Developmental Biology Section, and Center for Molecular Genetics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0116, USA
    Plant Cell Physiol 47:622-33. 2006
    T-DNA disruption mutations in the AtHKT1 gene have previously been shown to suppress the salt sensitivity of the sos3 mutant. However, both sos3 and athkt1 single mutants show sodium (Na+) hypersensitivity...
  14. pmc Microarray-based rapid cloning of an ion accumulation deletion mutant in Arabidopsis thaliana
    Ji Ming Gong
    Division of Biological Sciences, Cell and Developmental Biology Section and Center for Molecular Genetics, University of California at San Diego, La Jolla, CA 92093 0116, USA
    Proc Natl Acad Sci U S A 101:15404-9. 2004
    ..mutant FN1148 was identified as having a 523-bp genomic deletion within the second exon and intron of the AtHKT1 gene...
  15. pmc AtHKT1 facilitates Na+ homeostasis and K+ nutrition in planta
    Ana Rus
    Center for Plant Environmental Stress Physiology, Purdue University, West Lafayette, IN 47907 2010, USA
    Plant Physiol 136:2500-11. 2004
    Genetic and physiological data establish that Arabidopsis AtHKT1 facilitates Na(+) homeostasis in planta and by this function modulates K(+) nutrient status...
  16. ncbi The Na+ transporter AtHKT1;1 controls retrieval of Na+ from the xylem in Arabidopsis
    Romola Jane Davenport
    Department of Plant Sciences, Downing Street, Cambridge CB2 3EA, UK
    Plant Cell Environ 30:497-507. 2007
    ..hypotheses using (22)Na(+) flux measurements and ion accumulation assays in an hkt1;1 mutant and demonstrated that AtHKT1;1 contributes to the control of both root accumulation of Na(+) and retrieval of Na(+) from the xylem, but is not ..
  17. doi Characterization of ion contents and metabolic responses to salt stress of different Arabidopsis AtHKT1;1 genotypes and their parental strains
    Camilla B Hill
    Australian Centre for Plant Functional Genomics, School of Botany, University of Melbourne, Victoria 3010, Australia
    Mol Plant 6:350-68. 2013
    ..Cell-type-specific overexpression of AtHKT1;1 has been shown to prevent shoot Na(+) overaccumulation under salinity stress...
  18. doi Soil bacteria confer plant salt tolerance by tissue-specific regulation of the sodium transporter HKT1
    Huiming Zhang
    Texas Tech University, Department of Chemistry, Biochemistry and Biology Lubbock 79409, U S A
    Mol Plant Microbe Interact 21:737-44. 2008
    ..Consistent with HKT1 participation in GB03-induced salt tolerance, GB03 fails to rescue salt-stressed athkt1 mutants from stunted foliar growth and elevated total Na(+) whereas salt-stressed Na(+) export mutants sos3 show ..