Gene Symbol: HKL1
Description: hexokinase-like 1
Alias: ATHKL1, F11F12.18, F11F12_18, hexokinase-like 1, hexokinase-like 1
Species: thale cress

Top Publications

  1. Claeyssen E, Rivoal J. Isozymes of plant hexokinase: occurrence, properties and functions. Phytochemistry. 2007;68:709-31 pubmed
    ..Similarities and differences to known properties of animal and yeast HKs are also discussed as they may help to gain further insight into the functional adaptations of plant HKs. ..
  2. Karve A, Rauh B, Xia X, Kandasamy M, Meagher R, Sheen J, et al. Expression and evolutionary features of the hexokinase gene family in Arabidopsis. Planta. 2008;228:411-25 pubmed publisher
    ..Expression studies indicate that both HKL1 and HKL2 transcripts occur in most, if not all, plant tissues and that both proteins are targeted within cells to ..
  3. Giegé P, Heazlewood J, Roessner Tunali U, Millar A, Fernie A, Leaver C, et al. Enzymes of glycolysis are functionally associated with the mitochondrion in Arabidopsis cells. Plant Cell. 2003;15:2140-51 pubmed
  4. Karve A, Moore B. Function of Arabidopsis hexokinase-like1 as a negative regulator of plant growth. J Exp Bot. 2009;60:4137-49 pubmed publisher
    ..Since the AtHKL1 protein is predicted to bind glc, although with a relatively decreased affinity, a reverse genetics approach was ..
  5. Karve A, Xia X, Moore B. Arabidopsis Hexokinase-Like1 and Hexokinase1 form a critical node in mediating plant glucose and ethylene responses. Plant Physiol. 2012;158:1965-75 pubmed publisher
    Arabidopsis (Arabidopsis thaliana) Hexokinase-Like1 (HKL1) lacks glucose (Glc) phosphorylation activity and has been shown to act as a negative regulator of plant growth...
  6. Duncan O, Taylor N, Carrie C, Eubel H, Kubiszewski Jakubiak S, Zhang B, et al. Multiple lines of evidence localize signaling, morphology, and lipid biosynthesis machinery to the mitochondrial outer membrane of Arabidopsis. Plant Physiol. 2011;157:1093-113 pubmed publisher
  7. Koizumi S, Ohama N, Mizoi J, Shinozaki K, Yamaguchi Shinozaki K. Functional analysis of the Hikeshi-like protein and its interaction with HSP70 in Arabidopsis. Biochem Biophys Res Commun. 2014;450:396-400 pubmed publisher
    ..Our results suggest that HKL plays a positive role in the thermotolerance of Arabidopsis plants and cooperatively interacts with HSP70. ..