GRP7

Summary

Gene Symbol: GRP7
Description: cold, circadian rhythm, and rna binding 2
Alias: ''cold, ATGPR7, ATGRP7, CCR2, F2G1.4, GLYCINE RICH PROTEIN 7, GLYCINE-RICH RNA-BINDING PROTEIN 7, GR-RBP7, and rna binding 2, and rna binding 2'', circadian rhythm, cold, cold, circadian rhythm, and rna binding 2
Species: thale cress

Top Publications

  1. Kim J, Jung H, Lee H, Kim K, Goh C, Woo Y, et al. Glycine-rich RNA-binding protein 7 affects abiotic stress responses by regulating stomata opening and closing in Arabidopsis thaliana. Plant J. 2008;55:455-66 pubmed publisher
    ..Arabidopsis thaliana, on seed germination, seedling growth, and stress tolerance under high salinity, drought, or cold stress conditions...
  2. Heintzen C, Nater M, Apel K, Staiger D. AtGRP7, a nuclear RNA-binding protein as a component of a circadian-regulated negative feedback loop in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 1997;94:8515-20 pubmed
    ..A transcript encoding a glycine-rich RNA-binding protein, Atgrp7, in Arabidopsis thaliana undergoes circadian oscillations with peak levels in the evening...
  3. Lohr B, Streitner C, Steffen A, Lange T, Staiger D. A glycine-rich RNA-binding protein affects gibberellin biosynthesis in Arabidopsis. Mol Biol Rep. 2014;41:439-45 pubmed publisher
    The RNA-binding protein Arabidopsis thaliana glycine-rich RNA-binding protein 7 (AtGRP7) regulates the steady-state abundance of numerous target transcripts in A. thaliana...
  4. van Nocker S, Vierstra R. Two cDNAs from Arabidopsis thaliana encode putative RNA binding proteins containing glycine-rich domains. Plant Mol Biol. 1993;21:695-9 pubmed
    ..b>AtGRP7 and AtGRP8 encode proteins with a bipartite structure consisting of an amino-terminal putative RNA-binding domain ..
  5. Streitner C, Köster T, Simpson C, Shaw P, Danisman S, Brown J, et al. An hnRNP-like RNA-binding protein affects alternative splicing by in vivo interaction with transcripts in Arabidopsis thaliana. Nucleic Acids Res. 2012;40:11240-55 pubmed publisher
    ..Here, we show that the glycine-rich RNA-binding protein AtGRP7 influences AS in Arabidopsis thaliana...
  6. Schöning J, Streitner C, Meyer I, Gao Y, Staiger D. Reciprocal regulation of glycine-rich RNA-binding proteins via an interlocked feedback loop coupling alternative splicing to nonsense-mediated decay in Arabidopsis. Nucleic Acids Res. 2008;36:6977-87 pubmed publisher
    ..In addition to its own pre-mRNA, AtGRP8 negatively regulates the AtGRP7 transcript through promoting the formation of the equivalent alternatively spliced as_AtGRP7 transcript, leading ..
  7. Schüttpelz M, Schöning J, Doose S, Neuweiler H, Peters E, Staiger D, et al. Changes in conformational dynamics of mRNA upon AtGRP7 binding studied by fluorescence correlation spectroscopy. J Am Chem Soc. 2008;130:9507-13 pubmed publisher
    The clock-regulated RNA recognition motif (RRM)-containing protein AtGRP7 (Arabidopsis thaliana glycine-rich RNA-binding protein) influences the amplitude of its transcript oscillation at the post-transcriptional level...
  8. Cao S, Jiang L, Song S, Jing R, Xu G. AtGRP7 is involved in the regulation of abscisic acid and stress responses in Arabidopsis. Cell Mol Biol Lett. 2006;11:526-35 pubmed
    The Arabidopsis AtGRP7 gene, encoding a glycine-rich RNA-binding protein, has been shown to be involved in the regulation of a circadian-regulated negative feedback loop...
  9. Fu Z, Guo M, Jeong B, Tian F, Elthon T, Cerny R, et al. A type III effector ADP-ribosylates RNA-binding proteins and quells plant immunity. Nature. 2007;447:284-8 pubmed
    ..A. thaliana knockout lines defective in the glycine-rich RNA-binding protein GRP7 (also known as AtGRP7), a HopU1 substrate, were more susceptible than wild-type plants to P. syringae...

More Information

Publications24

  1. Hackmann C, Korneli C, Kutyniok M, Köster T, Wiedenlübbert M, Muller C, et al. Salicylic acid-dependent and -independent impact of an RNA-binding protein on plant immunity. Plant Cell Environ. 2014;37:696-706 pubmed publisher
    Plants overexpressing the RNA-binding protein AtGRP7 (AtGRP7-ox plants) constitutively express the PR-1 (PATHOGENESIS-RELATED-1), PR-2 and PR-5 transcripts associated with salicylic acid (SA)-mediated immunity and show enhanced resistance ..
  2. Schöning J, Streitner C, Page D, Hennig S, Uchida K, Wolf E, et al. Auto-regulation of the circadian slave oscillator component AtGRP7 and regulation of its targets is impaired by a single RNA recognition motif point mutation. Plant J. 2007;52:1119-30 pubmed
    The clock-regulated RNA-binding protein AtGRP7 (Arabidopsis thaliana glycine-rich RNA-binding protein) influences circadian oscillations of its transcript by negative feedback at the post-transcriptional level...
  3. Kim J, Park S, Kwak K, Kim Y, Kim J, Song J, et al. Cold shock domain proteins and glycine-rich RNA-binding proteins from Arabidopsis thaliana can promote the cold adaptation process in Escherichia coli. Nucleic Acids Res. 2007;35:506-16 pubmed
    ..role of plant CSDPs and GRPs in the cold response, two CSDPs (CSDP1 and CSDP2) and three GRPs (GRP2, GRP4 and GRP7) from Arabidopsis thaliana were investigated...
  4. Kwak K, Kim Y, Kang H. Characterization of transgenic Arabidopsis plants overexpressing GR-RBP4 under high salinity, dehydration, or cold stress. J Exp Bot. 2005;56:3007-16 pubmed
    ..expression, nucleic acid-binding property, and functional roles in plants subjected to various stresses including cold, high salinity, and dehydration...
  5. Streitner C, Danisman S, Wehrle F, Schöning J, Alfano J, Staiger D. The small glycine-rich RNA binding protein AtGRP7 promotes floral transition in Arabidopsis thaliana. Plant J. 2008;56:239-50 pubmed publisher
    The RNA binding protein AtGRP7 is part of a circadian slave oscillator in Arabidopsis thaliana that negatively autoregulates its own mRNA, and affects the levels of other transcripts...
  6. Jeong B, Lin Y, Joe A, Guo M, Korneli C, Yang H, et al. Structure function analysis of an ADP-ribosyltransferase type III effector and its RNA-binding target in plant immunity. J Biol Chem. 2011;286:43272-81 pubmed publisher
    ..plant cell it suppresses immunity by modifying RNA-binding proteins including the glycine-rich RNA-binding protein GRP7. The crystal structure of HopU1 at 2...
  7. Ziemienowicz A, Haasen D, Staiger D, Merkle T. Arabidopsis transportin1 is the nuclear import receptor for the circadian clock-regulated RNA-binding protein AtGRP7. Plant Mol Biol. 2003;53:201-12 pubmed
    ..hnRNP that shows high similarity to human hnRNP A1 and two small RNA-binding proteins from Arabidopsis, AtGRP7 and AtGRP8...
  8. Nicaise V, Joe A, Jeong B, Korneli C, Boutrot F, Westedt I, et al. Pseudomonas HopU1 modulates plant immune receptor levels by blocking the interaction of their mRNAs with GRP7. EMBO J. 2013;32:701-12 pubmed publisher
    ..HopU1 targets several RNA-binding proteins including GRP7, whose role in immunity is still unclear...
  9. Kwak K, Park S, Han J, Kim M, Oh S, Han Y, et al. Structural determinants crucial to the RNA chaperone activity of glycine-rich RNA-binding proteins 4 and 7 in Arabidopsis thaliana during the cold adaptation process. J Exp Bot. 2011;62:4003-11 pubmed publisher
    ..C-terminal glycine-rich domains of two Arabidopsis thaliana GRPs (AtGRP4 harbouring no RNA chaperone activity and AtGRP7 harbouring RNA chaperone activity) was assessed via domain swapping and mutation analyses...
  10. Schmal C, Reimann P, Staiger D. A circadian clock-regulated toggle switch explains AtGRP7 and AtGRP8 oscillations in Arabidopsis thaliana. PLoS Comput Biol. 2013;9:e1002986 pubmed publisher
    ..The transcripts encoding the RNA-binding proteins AtGRP7 (Arabidopsis thaliana Glycine Rich Protein 7) and AtGRP8 oscillate with evening peaks...
  11. Yang D, Kwak K, Kim M, Park S, Yang K, Kang H. Expression of Arabidopsis glycine-rich RNA-binding protein AtGRP2 or AtGRP7 improves grain yield of rice (Oryza sativa) under drought stress conditions. Plant Sci. 2014;214:106-12 pubmed publisher
    ..AtGRP2- or AtGRP7-expressing transgenic rice plants displayed similar phenotypes comparable with the wild-type plants under high ..
  12. Lee H, Kim J, Yoo S, Kang E, Han S, Yang K, et al. Different roles of glycine-rich RNA-binding protein7 in plant defense against Pectobacterium carotovorum, Botrytis cinerea, and tobacco mosaic viruses. Plant Physiol Biochem. 2012;60:46-52 pubmed publisher
    Glycine-rich RNA-binding protein7 (AtGRP7) has previously been demonstrated to confer plant defense against Pseudomonas syringae DC3000. Here, we show that AtGRP7 can play different roles in plant defense against diverse pathogens...
  13. Leder V, Lummer M, Tegeler K, Humpert F, Lewinski M, Schüttpelz M, et al. Mutational definition of binding requirements of an hnRNP-like protein in Arabidopsis using fluorescence correlation spectroscopy. Biochem Biophys Res Commun. 2014;453:69-74 pubmed publisher
    Arabidopsis thaliana glycine-rich RNA binding protein 7 (AtGRP7) is part of a negative feedback loop through which it regulates alternative splicing and steady-state abundance of its pre-mRNA...
  14. K ster T, Meyer K, Weinholdt C, Smith L, Lummer M, Speth C, et al. Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis. Nucleic Acids Res. 2014;42:9925-36 pubmed publisher
    The hnRNP-like glycine-rich RNA-binding protein AtGRP7 regulates pre-mRNA splicing in Arabidopsis. Here we used small RNA-seq to show that AtGRP7 also affects the miRNA inventory...
  15. Xiao J, Li C, Xu S, Xing L, Xu Y, Chong K. JACALIN-LECTIN LIKE1 Regulates the Nuclear Accumulation of GLYCINE-RICH RNA-BINDING PROTEIN7, Influencing the RNA Processing of FLOWERING LOCUS C Antisense Transcripts and Flowering Time in Arabidopsis. Plant Physiol. 2015;169:2102-17 pubmed publisher
    ..Genetic analysis revealed that AtJAC1's function is mostly dependent on GLYCINE-RICH RNA-BINDING PROTEIN7 (GRP7), an upstream regulator of FLC...