Gene Symbol: GRH1
Description: GRR1-like protein 1
Alias: A. THALIANA GERMIN-LIKE PROTEIN 1, AFB1, ATFBL18, ATGER1, ATGRH1, AUXIN SIGNALING F BOX PROTEIN 1, F4C21.11, F4C21_11, GRR1-like protein 1, GRR1-like protein 1
Species: thale cress
Dharmasiri N, Dharmasiri S, Estelle M. The F-box protein TIR1 is an auxin receptor. Nature. 2005;435:441-5 pubmed
..Finally, TIR1 synthesized in insect cells binds Aux/IAA proteins in an auxin-dependent manner. Together, these results indicate that TIR1 is an auxin receptor that mediates Aux/IAA degradation and auxin-regulated transcription. ..
Dharmasiri N, Dharmasiri S, Weijers D, Lechner E, Yamada M, Hobbie L, et al
. Plant development is regulated by a family of auxin receptor F box proteins. Dev Cell. 2005;9:109-19 pubmed
..Here we show that three additional F box proteins, called AFB1, 2, and 3, also regulate auxin response...
Thelander M, Fredriksson D, Schouten J, Hoge J, Ronne H. Cloning by pathway activation in yeast: identification of an Arabidopsis thaliana F-box protein that can turn on glucose repression. Plant Mol Biol. 2002;49:69-79 pubmed
..Six clones were characterized. One of them codes for AtGRH1, a new F-box protein that shows similarity to GRR1, a yeast protein involved in glucose repression...
Dharmasiri S, Dharmasiri N, Hellmann H, Estelle M. The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis. EMBO J. 2003;22:1762-70 pubmed
..In addition, we show that RCE1 interacts directly with the RING protein RBX1 and is present in a stable complex with SCF. We propose that RBX1 functions as an E3 for RUB modification of CUL1. ..
Navarro L, Dunoyer P, Jay F, Arnold B, Dharmasiri N, Estelle M, et al
. A plant miRNA contributes to antibacterial resistance by repressing auxin signaling. Science. 2006;312:436-9 pubmed
..Repression of auxin signaling restricts P. syringae growth, implicating auxin in disease susceptibility and miRNA-mediated suppression of auxin signaling in resistance. ..
Cecchetti V, Altamura M, Falasca G, Costantino P, Cardarelli M. Auxin regulates Arabidopsis anther dehiscence, pollen maturation, and filament elongation. Plant Cell. 2008;20:1760-74 pubmed publisher
..In agreement with the timing of auxin effects, the TIR1, AFB1, AFB2, and AFB3 auxin receptor-encoding genes are transcribed in anthers only during late stages of development ..
Parry G, Calderon Villalobos L, Prigge M, Peret B, Dharmasiri S, Itoh H, et al
. Complex regulation of the TIR1/AFB family of auxin receptors. Proc Natl Acad Sci U S A. 2009;106:22540-5 pubmed publisher
..Further, we demonstrate that TIR1, AFB2, and AFB3, but not AFB1 exhibit significant posttranscriptional regulation...
Calderon Villalobos L, Lee S, de Oliveira C, Ivetac A, Brandt W, Armitage L, et al
. A combinatorial TIR1/AFB-Aux/IAA co-receptor system for differential sensing of auxin. Nat Chem Biol. 2012;8:477-85 pubmed publisher
..This co-receptor system broadens the effective concentration range of the hormone and may contribute to the complexity of auxin response. ..