Gene Symbol: GPAT9
Description: glycerol-3-phosphate acyltransferase 9
Alias: MUP24.4, MUP24_4, glycerol-3-phosphate acyltransferase 9, glycerol-3-phosphate acyltransferase 9
Species: thale cress
Beigneux A, Vergnes L, Qiao X, Quatela S, Davis R, Watkins S, et al
. Agpat6--a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium. J Lipid Res. 2006;47:734-44 pubmed
..Thus, we identified a novel glycerolipid acyltransferase of the ER, AGPAT6, which is crucial for the production of milk fat by the mammary gland. ..
Gidda S, Shockey J, Rothstein S, Dyer J, Mullen R. Arabidopsis thaliana GPAT8 and GPAT9 are localized to the ER and possess distinct ER retrieval signals: functional divergence of the dilysine ER retrieval motif in plant cells. Plant Physiol Biochem. 2009;47:867-79 pubmed publisher
..relatively large Arabidopsis thaliana GPAT family, including GPAT8, which is involved in cutin biosynthesis, and GPAT9, which is a new putative GPAT that has extensive homology with a GPAT from mammalian cells involved in storage oil ..
Shockey J, Regmi A, Cotton K, Adhikari N, Browse J, Bates P. Identification of Arabidopsis GPAT9 (At5g60620) as an Essential Gene Involved in Triacylglycerol Biosynthesis. Plant Physiol. 2016;170:163-79 pubmed publisher
..Together, these results suggest that GPAT9 is the ER-localized GPAT enzyme responsible for plant membrane lipid and oil biosynthesis.
Singer S, Chen G, Mietkiewska E, Tomasi P, Jayawardhane K, Dyer J, et al
. Arabidopsis GPAT9 contributes to synthesis of intracellular glycerolipids but not surface lipids. J Exp Bot. 2016;67:4627-38 pubmed publisher
..GPATs 4-8 have been shown to be involved in the production of extracellular lipid barrier polyesters. Recently, GPAT9 was reported to be essential for triacylglycerol (TAG) biosynthesis in developing Arabidopsis seeds...