Gene Symbol: GLX2-1
Description: glyoxalase 2-1
Alias: GLY1, GLYOXALASE II, T1O24.17, glyoxalase 2-1, glyoxalase 2-1
Species: thale cress

Top Publications

  1. Maiti M, Krishnasamy S, Owen H, Makaroff C. Molecular characterization of glyoxalase II from Arabidopsis thaliana. Plant Mol Biol. 1997;35:471-81 pubmed
    b>Glyoxalase II is part of the glutathione-dependent glyoxalase detoxification system...
  2. Limphong P, Crowder M, Bennett B, Makaroff C. Arabidopsis thaliana GLX2-1 contains a dinuclear metal binding site, but is not a glyoxalase 2. Biochem J. 2009;417:323-30 pubmed publisher
    ..These results demonstrate that Arabidopsis GLX2-1 is a novel member of the metallo-beta-lactamase superfamily. ..
  3. Limphong P, Nimako G, Thomas P, Fast W, Makaroff C, Crowder M. Arabidopsis thaliana mitochondrial glyoxalase 2-1 exhibits beta-lactamase activity. Biochemistry. 2009;48:8491-3 pubmed publisher
    ..Glx2-1 can hydrolyze cephalosporins and carbapenems, albeit with rate constants slower than those of most metallo-beta-lactamases. The potential role of a beta-lactamase in the mitochondria of plant cells is briefly discussed. ..
  4. Devanathan S, Erban A, Perez Torres R, Kopka J, Makaroff C. Arabidopsis thaliana glyoxalase 2-1 is required during abiotic stress but is not essential under normal plant growth. PLoS ONE. 2014;9:e95971 pubmed publisher
    ..Overall our results suggest that Arabidopsis thaliana GLX2-1 is not essential during normal plant life, but is required during specific stress conditions. ..