Gene Symbol: FPA
Description: RNA binding protein
Alias: T1O24.15, RNA binding protein
Species: thale cress
Sonmez C, Bäurle I, Magusin A, Dreos R, Laubinger S, Weigel D, et al
. RNA 3' processing functions of Arabidopsis FCA and FPA limit intergenic transcription. Proc Natl Acad Sci U S A. 2011;108:8508-13 pubmed publisher
The RNA-binding proteins FCA and FPA were identified based on their repression of the flowering time regulator FLC but have since been shown to have widespread roles in the Arabidopsis thaliana genome...
Bäurle I, Smith L, Baulcombe D, Dean C. Widespread role for the flowering-time regulators FCA and FPA in RNA-mediated chromatin silencing. Science. 2007;318:109-12 pubmed
The RRM-domain proteins FCA and FPA have previously been characterized as flowering-time regulators in Arabidopsis. We show that they are required for RNA-mediated chromatin silencing of a range of loci in the genome...
Hornyik C, Terzi L, Simpson G. The spen family protein FPA controls alternative cleavage and polyadenylation of RNA. Dev Cell. 2010;18:203-13 pubmed publisher
..We show that FPA functions redundantly with FCA, another RNA binding protein that controls flowering and RNA silencing, to control the expression of alternatively polyadenylated ..
Doyle M, Bizzell C, Keller M, Michaels S, Song J, Noh Y, et al
. HUA2 is required for the expression of floral repressors in Arabidopsis thaliana. Plant J. 2005;41:376-85 pubmed
..hua2 mutations suppress late flowering by reducing the expression of several MADS genes that act as floral repressors including FLOWERING LOCUS C (FLC ) and FLOWERING LOCUS M (FLM ). ..
Zhang Y, Li X, Goodrich J, Wu C, Wei H, Yang S, et al
. Reduced function of the RNA-binding protein FPA rescues a T-DNA insertion mutant in the Arabidopsis ZHOUPI gene by promoting transcriptional read-through. Plant Mol Biol. 2016;91:549-61 pubmed publisher
..SPZ2 encodes an RNA-binding protein, FPA, which is known to regulate polyadenylation site selection...
Schomburg F, Patton D, Meinke D, Amasino R. FPA, a gene involved in floral induction in Arabidopsis, encodes a protein containing RNA-recognition motifs. Plant Cell. 2001;13:1427-36 pubmed
b>FPA is a gene that regulates flowering time in Arabidopsis via a pathway that is independent of daylength (the autonomous pathway). Mutations in FPA result in extremely delayed flowering. FPA was identified by means of positional cloning...
Zhang Y, Rataj K, Simpson G, Tong L. Crystal Structure of the SPOC Domain of the Arabidopsis Flowering Regulator FPA. PLoS ONE. 2016;11:e0160694 pubmed publisher
The Arabidopsis protein FPA controls flowering time by regulating the alternative 3'-end processing of the FLOWERING LOCUS (FLC) antisense RNA...
Duc C, Sherstnev A, Cole C, Barton G, Simpson G. Transcription termination and chimeric RNA formation controlled by Arabidopsis thaliana FPA. PLoS Genet. 2013;9:e1003867 pubmed publisher
..Although widespread, few regulators of this process are known. The Arabidopsis thaliana protein FPA is a rare example of a trans-acting regulator of poly(A) site choice...