Gene Symbol: FNR1
Description: ferredoxin-NADP[+]-oxidoreductase 1
Alias: ATLFNR1, FERREDOXIN:NADP(H) OXIDOREDUCTASE, K2A18.27, K2A18_27, LEAF FNR 1, LFNR1, ferredoxin-NADP(+)-oxidoreductase 1, leaf-type chloroplast-targeted FNR 1, ferredoxin-NADP[+]-oxidoreductase 1
Species: thale cress
Products:     FNR1

Top Publications

  1. Lintala M, Allahverdiyeva Y, Kangasjärvi S, Lehtimäki N, Keranen M, Rintamäki E, et al. Comparative analysis of leaf-type ferredoxin-NADP oxidoreductase isoforms in Arabidopsis thaliana. Plant J. 2009;57:1103-15 pubmed publisher
    ..ferredoxin-NADP(+) oxidoreductase (FNR) isoforms in Arabidopsis thaliana were studied using T-DNA insertion line fnr1 and RNAi line fnr2...
  2. Lehtimäki N, Koskela M, Dahlström K, Pakula E, Lintala M, Scholz M, et al. Posttranslational modifications of FERREDOXIN-NADP+ OXIDOREDUCTASE in Arabidopsis chloroplasts. Plant Physiol. 2014;166:1764-76 pubmed publisher
  3. Yuan S, Zhang Z, Zheng C, Zhao Z, Wang Y, Feng L, et al. Arabidopsis cryptochrome 1 functions in nitrogen regulation of flowering. Proc Natl Acad Sci U S A. 2016;113:7661-6 pubmed publisher
    ..g., GI and CO). Taken together, our results suggest that N signaling functions as a modulator of nuclear CRY1 protein abundance, as well as the input signal for the central circadian clock to interfere with the normal flowering process. ..
  4. Lintala M, Lehtimäki N, Benz J, Jungfer A, Soll J, Aro E, et al. Depletion of leaf-type ferredoxin-NADP(+) oxidoreductase results in the permanent induction of photoprotective mechanisms in Arabidopsis chloroplasts. Plant J. 2012;70:809-17 pubmed publisher
    ..Nevertheless, the FNR isoforms also display distinct molecular phenotypes, as only the FNR1 is able to directly bind to the thylakoid membrane...
  5. Michaeli S, Honig A, Levanony H, Peled Zehavi H, Galili G. Arabidopsis ATG8-INTERACTING PROTEIN1 is involved in autophagy-dependent vesicular trafficking of plastid proteins to the vacuole. Plant Cell. 2014;26:4084-101 pubmed publisher
    ..Taken together, our results implicate ATI1 in autophagic plastid-to-vacuole trafficking through its ability to interact with both plastid proteins and ATG8 of the core autophagy machinery. ..
  6. Hanke G, Endo T, Satoh F, Hase T. Altered photosynthetic electron channelling into cyclic electron flow and nitrite assimilation in a mutant of ferredoxin:NADP(H) reductase. Plant Cell Environ. 2008;31:1017-28 pubmed publisher
    ..Taken together, our results demonstrate the integral role played by FNR isoform and location in the partitioning of photosynthetic reducing power. ..
  7. Stael S, Bayer R, Mehlmer N, Teige M. Protein N-acylation overrides differing targeting signals. FEBS Lett. 2011;585:517-522 pubmed publisher
  8. DalCorso G, Pesaresi P, Masiero S, Aseeva E, Schünemann D, Finazzi G, et al. A complex containing PGRL1 and PGR5 is involved in the switch between linear and cyclic electron flow in Arabidopsis. Cell. 2008;132:273-85 pubmed publisher
    ..Plants lacking PGRL1 show perturbation of CEF, similar to PGR5-deficient plants. We find that PGRL1 and PGR5 interact physically and associate with PSI. We therefore propose that the PGRL1-PGR5 complex facilitates CEF in eukaryotes. ..
  9. Benz J, Stengel A, Lintala M, Lee Y, Weber A, Philippar K, et al. Arabidopsis Tic62 and ferredoxin-NADP(H) oxidoreductase form light-regulated complexes that are integrated into the chloroplast redox poise. Plant Cell. 2009;21:3965-83 pubmed publisher
    ..Association with Tic62 stabilizes FNR and is involved in its dynamic and light-dependent membrane tethering. ..

More Information


  1. Puthiyaveetil S, Ibrahim I, Jelicic B, Tomasic A, Fulgosi H, Allen J. Transcriptional control of photosynthesis genes: the evolutionarily conserved regulatory mechanism in plastid genome function. Genome Biol Evol. 2010;2:888-96 pubmed publisher
    ..Plastid genome function permits adaptation of the photosynthetic apparatus to changing environmental conditions of light quantity and quality. ..
  2. Lintala M, Allahverdiyeva Y, Kidron H, Piippo M, Battchikova N, Suorsa M, et al. Structural and functional characterization of ferredoxin-NADP+-oxidoreductase using knock-out mutants of Arabidopsis. Plant J. 2007;49:1041-52 pubmed
    ..thaliana, the chloroplast-targeted enzyme ferredoxin-NADP+-oxidoreductase (FNR) exists as two isoforms, AtLFNR1 and AtLFNR2, encoded by the genes At5g66190 and At1g20020, respectively...
  3. Xu Y, Wang B, Zhu Y. Identification of proteins expressed at extremely low level in Arabidopsis leaves. Biochem Biophys Res Commun. 2007;358:808-12 pubmed
    ..Our results suggest that polyU or similar media may be combined with 2-DE techniques to identify cellular proteins with extremely low transcription levels to fulfill specific research needs. ..
  4. Lintala M, Schuck N, Thormählen I, Jungfer A, Weber K, Weber A, et al. Arabidopsis tic62 trol mutant lacking thylakoid-bound ferredoxin-NADP+ oxidoreductase shows distinct metabolic phenotype. Mol Plant. 2014;7:45-57 pubmed publisher
    ..Surface plasmon resonance assays showed that the two FNR isoforms, LFNR1 and LFNR2, are bound to the thylakoid membrane via the C-terminal domains of Tic62 and TROL proteins in a pH-..
  5. Kozuleva M, Goss T, Twachtmann M, Rudi K, Trapka J, Selinski J, et al. Ferredoxin:NADP(H) Oxidoreductase Abundance and Location Influences Redox Poise and Stress Tolerance. Plant Physiol. 2016;172:1480-1493 pubmed
    ..In fnr1 knock-outs, the NADP(H) and glutathione pools are more oxidized relative to the wild type, and the photoprotective ..