FKF1

Summary

Gene Symbol: FKF1
Description: flavin-binding, kelch repeat, f box 1
Alias: ADO3, T23K23.10, T23K23_10, f box 1, flavin-binding, kelch repeat
Species: thale cress

Top Publications

  1. ncbi FKF1 F-box protein mediates cyclic degradation of a repressor of CONSTANS in Arabidopsis
    Takato Imaizumi
    Department of Cell Biology, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Science 309:293-7. 2005
  2. pmc FKF1 conveys timing information for CONSTANS stabilization in photoperiodic flowering
    Young Hun Song
    Department of Biology, University of Washington, Seattle, WA 98195, USA
    Science 336:1045-9. 2012
  3. doi LOV KELCH PROTEIN2 and ZEITLUPE repress Arabidopsis photoperiodic flowering under non-inductive conditions, dependent on FLAVIN-BINDING KELCH REPEAT F-BOX1
    Tomoyuki Takase
    Department of Life Science, Faculty of Science, Gakushuin University, 1 5 1 Mejiro, Toshima ku, Tokyo 171 8588, Japan
    Plant J 67:608-21. 2011
  4. pmc Kinetics of conformational changes of the FKF1-LOV domain upon photoexcitation
    Yusuke Nakasone
    Department of Chemistry, Graduate School of Science, Kyoto University, Kyoto, Japan
    Biophys J 99:3831-9. 2010
  5. pmc F-box proteins FKF1 and LKP2 act in concert with ZEITLUPE to control Arabidopsis clock progression
    Antoine Baudry
    Section of Cell and Developmental Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, California 92093, USA
    Plant Cell 22:606-22. 2010
  6. ncbi [Molecular mechanism by which plant determines flowering timing with circadian clock]
    Mariko Sawa
    Tanpakushitsu Kakusan Koso 53:739-46. 2008
  7. pmc FKF1 and GIGANTEA complex formation is required for day-length measurement in Arabidopsis
    Mariko Sawa
    Department of Biochemistry, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Science 318:261-5. 2007
  8. ncbi ZEITLUPE is a circadian photoreceptor stabilized by GIGANTEA in blue light
    Woe Yeon Kim
    Department of Plant Cellular and Molecular Biology Plant Biotechnology Center, Ohio State University, 054 Rightmire Hall, 1060 Carmack Road, Columbus, Ohio 43210, USA
    Nature 449:356-60. 2007
  9. ncbi Photoreaction cycle of the light, oxygen, and voltage domain in FKF1 determined by low-temperature absorption spectroscopy
    Kazunori Zikihara
    Department of Biological Science, Graduate School of Science, Osaka Prefecture University, 1 1 Gakuencho, Sakai, Osaka 599 8531, Japan
    Biochemistry 45:10828-37. 2006
  10. ncbi Identification of LOV KELCH PROTEIN2 (LKP2)-interacting factors that can recruit LKP2 to nuclear bodies
    Yosuke Fukamatsu
    Division of Gene Research, Life Science Research Center, Kagawa University, 2393 Ikenobe, Miki cho Kita gun, Kagawa, 761 0795 Japan
    Plant Cell Physiol 46:1340-9. 2005

Scientific Experts

  • Masayoshi Nakasako
  • Mariko Sawa
  • Takato Imaizumi
  • Young Hun Song
  • Steve A Kay
  • Kazunori Zikihara
  • Tomohiro Kiyosue
  • Woe Yeon Kim
  • Masahiro Yasuhara
  • Tomoyuki Takase
  • Yusuke Nakasone
  • Antoine Baudry
  • Satoru Tokutomi
  • Yosuke Fukamatsu
  • David E Somers
  • Norihisa Ihara
  • Yoko Tokioka
  • Motoaki Seki
  • Kazuo Shinozaki
  • Naoki Takahashi
  • Paloma Mas
  • Benjamin J To
  • Andrew J Millar
  • Robert W Smith
  • Yuji Miyazaki
  • Yumiko Yamada
  • Yuuki Nishiyama
  • Haruna Tanihigashi
  • Yasunobu Ogura
  • Rossana Henriques
  • Elaine M Tobin
  • Masahide Terazima
  • D C Nelson
  • Sheen Lu
  • Jose L Pruneda-Paz
  • Nam Hai Chua
  • Alexander A Strait
  • Takatoshi Kiba
  • Shogo Ito
  • Hong Gil Nam
  • Sung Suk Suh
  • Linqu Han
  • Sumire Fujiwara
  • Joanna Putterill
  • Yumi Kim
  • Karine David
  • Jeongsik Kim
  • Hideki Kandori
  • Takeshi Todo
  • Daisuke Matsuoka
  • Tatsuya Iwata
  • Shouhei Fujita
  • Frank G Harmon
  • Thomas F Schultz
  • Lindsey A Ho
  • Syunya Mitsui
  • Rieko Takanabe
  • Hirofumi Kuroda
  • Takashi Hirayama
  • Akihiro Komatsu
  • Shunya Mitsui
  • Takashi Kuromori
  • Minami Matsui
  • Hiroaki Shimada
  • Hiroshi Hirano
  • Hien G Tran
  • Trevor E Swartz
  • Winslow R Briggs
  • M A Cohen
  • J Lasswell
  • B Bartel
  • L E Rogg

Detail Information

Publications16

  1. ncbi FKF1 F-box protein mediates cyclic degradation of a repressor of CONSTANS in Arabidopsis
    Takato Imaizumi
    Department of Cell Biology, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Science 309:293-7. 2005
    ..FLAVIN-BINDING, KELCH REPEAT, F-BOX 1 (FKF1) protein regulates CO transcription, although the molecular mechanism is unknown...
  2. pmc FKF1 conveys timing information for CONSTANS stabilization in photoperiodic flowering
    Young Hun Song
    Department of Biology, University of Washington, Seattle, WA 98195, USA
    Science 336:1045-9. 2012
    ..Here, we demonstrate that FLAVIN-BINDING, KELCH REPEAT, F-BOX 1 (FKF1) protein stabilizes CO protein in the afternoon in long days...
  3. doi LOV KELCH PROTEIN2 and ZEITLUPE repress Arabidopsis photoperiodic flowering under non-inductive conditions, dependent on FLAVIN-BINDING KELCH REPEAT F-BOX1
    Tomoyuki Takase
    Department of Life Science, Faculty of Science, Gakushuin University, 1 5 1 Mejiro, Toshima ku, Tokyo 171 8588, Japan
    Plant J 67:608-21. 2011
    LOV KELCH PROTEIN2 (LKP2), ZEITLUPE (ZTL)/LOV KELCH PROTEIN1 (LKP1) and FLAVIN-BINDING KELCH REPEAT F-BOX1 (FKF1) constitute a family of Arabidopsis F-box proteins that regulate the circadian clock...
  4. pmc Kinetics of conformational changes of the FKF1-LOV domain upon photoexcitation
    Yusuke Nakasone
    Department of Chemistry, Graduate School of Science, Kyoto University, Kyoto, Japan
    Biophys J 99:3831-9. 2010
    ..dynamics of a light-oxygen-voltage (LOV) domain from the blue light sensor protein, FKF1 (flavin-binding Kelch repeat F-box) was studied by means of the pulsed laser-induced transient grating method...
  5. pmc F-box proteins FKF1 and LKP2 act in concert with ZEITLUPE to control Arabidopsis clock progression
    Antoine Baudry
    Section of Cell and Developmental Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, California 92093, USA
    Plant Cell 22:606-22. 2010
    ..Here, we report that FLAVIN BINDING, KELCH REPEAT, F-BOX1 (FKF1) and LOV KELCH PROTEIN2 (LKP2) play similar roles to ZTL in the circadian clock ..
  6. ncbi [Molecular mechanism by which plant determines flowering timing with circadian clock]
    Mariko Sawa
    Tanpakushitsu Kakusan Koso 53:739-46. 2008
  7. pmc FKF1 and GIGANTEA complex formation is required for day-length measurement in Arabidopsis
    Mariko Sawa
    Department of Biochemistry, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Science 318:261-5. 2007
    ..The FLAVIN-BINDING, KELCH REPEAT, F-BOX 1 (FKF1), and GIGANTEA (GI) proteins regulate CO transcription in Arabidopsis...
  8. ncbi ZEITLUPE is a circadian photoreceptor stabilized by GIGANTEA in blue light
    Woe Yeon Kim
    Department of Plant Cellular and Molecular Biology Plant Biotechnology Center, Ohio State University, 054 Rightmire Hall, 1060 Carmack Road, Columbus, Ohio 43210, USA
    Nature 449:356-60. 2007
    ..This mechanism of establishing and sustaining robust oscillations of ZTL results in the high-amplitude TOC1 rhythms necessary for proper clock function...
  9. ncbi Photoreaction cycle of the light, oxygen, and voltage domain in FKF1 determined by low-temperature absorption spectroscopy
    Kazunori Zikihara
    Department of Biological Science, Graduate School of Science, Osaka Prefecture University, 1 1 Gakuencho, Sakai, Osaka 599 8531, Japan
    Biochemistry 45:10828-37. 2006
    Flavin-binding Kelch repeat F-box (FKF1) protein plays important roles in the photoregulation of flowering in Arabidopsis...
  10. ncbi Identification of LOV KELCH PROTEIN2 (LKP2)-interacting factors that can recruit LKP2 to nuclear bodies
    Yosuke Fukamatsu
    Division of Gene Research, Life Science Research Center, Kagawa University, 2393 Ikenobe, Miki cho Kita gun, Kagawa, 761 0795 Japan
    Plant Cell Physiol 46:1340-9. 2005
    ..The CCT motif in CO or COL1 was not sufficient for interaction with LKP2. LKP2 recognized CO with F-box and kelch repeat-containing regions, while it recognized COL1 with an LOV domain...
  11. ncbi Quaternary structure of LOV-domain containing polypeptide of Arabidopsis FKF1 protein
    Masayoshi Nakasako
    Department of Physics, Faculty of Science and Technology, Keio University, 3 14 1 Hiyoshi, Kohoku Ku, Kanagawa 223 8522, Japan
    FEBS Lett 579:1067-71. 2005
    Flavin-binding, Kelch repeat, F-box (FKF1) protein is a photoreceptor to regulate flowering of Arabidopsis. The protein has a light, oxygen and voltage (LOV)-sensing domain binding a flavin mononucleotide...
  12. ncbi Identification of ASK and clock-associated proteins as molecular partners of LKP2 (LOV kelch protein 2) in Arabidopsis
    Masahiro Yasuhara
    Gene Research Center, Kagawa University, 2393 Ikenobe, Miki cho Kita gun, Kagawa 761 0795, Japan
    J Exp Bot 55:2015-27. 2004
    The ADO/FKF/LKP/ZTL family of proteins of Arabidopsis thaliana Heynh. have a LOV domain, an F-box motif, and a kelch repeat region...
  13. ncbi Expression and interaction analysis of Arabidopsis Skp1-related genes
    Naoki Takahashi
    Plant Function Exploration Team, Plant Functional Genomics Research Group, Genomic Sciences Center, RIKEN Yokohama Institute, 1 7 22 Suyehiro cho, Tsurumi ku, Yokohama, Kanagawa, 230 0045 Japan
    Plant Cell Physiol 45:83-91. 2004
    ..As a result, we found diverse binding specificities: ASK1, ASK2, ASK11 and ASK12 interacted well with COI1, FKF1, UFO-like protein, LRR-containing F-box proteins, and other F-box proteins with unknown C-terminal motifs...
  14. ncbi Targeted degradation of TOC1 by ZTL modulates circadian function in Arabidopsis thaliana
    Paloma Mas
    Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
    Nature 426:567-70. 2003
    ..Our results show that the TOC1-ZTL interaction is important in the control of TOC1 protein stability, and is probably responsible for the regulation of circadian period by the clock...
  15. ncbi FKF1 is essential for photoperiodic-specific light signalling in Arabidopsis
    Takato Imaizumi
    Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
    Nature 426:302-6. 2003
    ..Here we show that the clock-controlled FLAVIN-BINDING, KELCH REPEAT, F-BOX (FKF1) protein has an essential role in generating the diurnal CO peak and that this function is ..
  16. ncbi FKF1, a clock-controlled gene that regulates the transition to flowering in Arabidopsis
    D C Nelson
    Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77005, USA
    Cell 101:331-40. 2000
    ..We isolated a late-flowering Arabidopsis mutant, fkf1, that is rescued by vemalization or gibberellin treatment...