Gene Symbol: EMF2
Description: VEFS-Box of polycomb protein
Alias: AT5G51240, AtEMF2, CYR1, CYTOKININ RESISTANT 1, EMBRYONIC FLOWER 2, MWD22.18, MWD22_18, VEF2, VEFS-Box of polycomb protein
Species: thale cress

Top Publications

  1. Chanvivattana Y, Bishopp A, Schubert D, Stock C, Moon Y, Sung Z, et al. Interaction of Polycomb-group proteins controlling flowering in Arabidopsis. Development. 2004;131:5263-76 pubmed
    In Arabidopsis, the EMBYRONIC FLOWER2 (EMF2), VERNALISATION2 (VRN2) and FERTILISATION INDEPENDENT ENDOSPERM2 (FIS2) genes encode related Polycomb-group (Pc-G) proteins...
  2. Kim S, Zhu T, Sung Z. Epigenetic regulation of gene programs by EMF1 and EMF2 in Arabidopsis. Plant Physiol. 2010;152:516-28 pubmed publisher
    ..EMF1 encodes a putative transcriptional regulator, while EMF2 encodes a Polycomb group (PcG) protein...
  3. Yoshida N, Yanai Y, Chen L, Kato Y, Hiratsuka J, Miwa T, et al. EMBRYONIC FLOWER2, a novel polycomb group protein homolog, mediates shoot development and flowering in Arabidopsis. Plant Cell. 2001;13:2471-81 pubmed
    ..Loss-of-function mutations in the EMBRYONIC FLOWER genes (EMF1 and EMF2) cause Arabidopsis to flower directly, bypassing vegetative shoot growth...
  4. Chen L, Cheng J, Castle L, Sung Z. EMF genes regulate Arabidopsis inflorescence development. Plant Cell. 1997;9:2011-24 pubmed
    Mutations in EMBRYONIC FLOWER (EMF) genes EMF1 and EMF2 abolish rosette development, and the mutants produce either a much reduced inflorescence or a transformed flower...
  5. Tang X, Lim M, Pelletier J, Tang M, Nguyen V, Keller W, et al. Synergistic repression of the embryonic programme by SET DOMAIN GROUP 8 and EMBRYONIC FLOWER 2 in Arabidopsis seedlings. J Exp Bot. 2012;63:1391-404 pubmed publisher
    ..made and formation of somatic embryos was observed on mutant seedlings with mutations in both SDG8 and EMF2 (EMBRYONIC FLOWER 2)...
  6. Lodha M, Marco C, Timmermans M. The ASYMMETRIC LEAVES complex maintains repression of KNOX homeobox genes via direct recruitment of Polycomb-repressive complex2. Genes Dev. 2013;27:596-601 pubmed publisher
    ..Combined with recent studies in mammals, our findings reveal a conserved paradigm to epigenetically regulate homeobox gene expression during development. ..
  7. Liang S, Hartwig B, Perera P, Mora García S, de Leau E, Thornton H, et al. Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2. PLoS Genet. 2015;11:e1005660 pubmed publisher
  8. Stetter M, Schmid K, Ludewig U. Uncovering genes and ploidy involved in the high diversity in root hair density, length and response to local scarce phosphate in Arabidopsis thaliana. PLoS ONE. 2015;10:e0120604 pubmed publisher
    ..Knock-out mutants in identified candidate genes (CYR1, At1g32360 and RLP48) were isolated and differences in root hair traits in the mutants were confirmed...
  9. Jullien P, Katz A, Oliva M, Ohad N, Berger F. Polycomb group complexes self-regulate imprinting of the Polycomb group gene MEDEA in Arabidopsis. Curr Biol. 2006;16:486-92 pubmed
    ..This feedback loop ensures a complete maternal control of MEA expression from both parental alleles and might have provided a template for evolution of imprinting in plants. ..

More Information


  1. Kim S, Lee J, Eshed Williams L, Zilberman D, Sung Z. EMF1 and PRC2 cooperate to repress key regulators of Arabidopsis development. PLoS Genet. 2012;8:e1002512 pubmed publisher
    ..Transcriptome analysis, coupled with the H3K27me3 pattern, of EMF1_K27 genes in emf1 and PRC2 mutants showed that EMF1 represses gene activities via diverse mechanisms and plays a novel role in the PcG mechanism. ..
  2. Derkacheva M, Steinbach Y, Wildhaber T, Mozgová I, Mahrez W, Nanni P, et al. Arabidopsis MSI1 connects LHP1 to PRC2 complexes. EMBO J. 2013;32:2073-85 pubmed publisher
    ..The LHP1-MSI1 interaction forms a positive feedback loop to recruit PRC2 to chromatin that carries H3K27me3. Consequently, this can provide a mechanism for the faithful inheritance of local epigenetic information through replication. ..