EFS

Summary

Gene Symbol: EFS
Description: histone-lysine N-methyltransferase
Alias: ASH1 HOMOLOG 2, ASHH2, CAROTENOID CHLOROPLAST REGULATORY1, CCR1, EARLY FLOWERING IN SHORT DAYS, LAZ2, LAZARUS 2, SDG8, SET DOMAIN GROUP 8, T14N5.15, T14N5_15, histone-lysine N-methyltransferase
Species: thale cress

Top Publications

  1. Cazzonelli C, Cuttriss A, Cossetto S, Pye W, Crisp P, Whelan J, et al. Regulation of carotenoid composition and shoot branching in Arabidopsis by a chromatin modifying histone methyltransferase, SDG8. Plant Cell. 2009;21:39-53 pubmed publisher
    ..We report the cloning of the CAROTENOID CHLOROPLAST REGULATORY1 (CCR1) gene...
  2. Grini P, Thorstensen T, Alm V, Vizcay Barrena G, Windju S, Jørstad T, et al. The ASH1 HOMOLOG 2 (ASHH2) histone H3 methyltransferase is required for ovule and anther development in Arabidopsis. PLoS ONE. 2009;4:e7817 pubmed publisher
    ..The Arabidopsis ASH1 HOMOLOG 2 (ASHH2) protein (also called SDG8, EFS and CCR1) has been suggested to methylate H3K4 and/or H3K36 and is ..
  3. Dong G, Ma D, Li J. The histone methyltransferase SDG8 regulates shoot branching in Arabidopsis. Biochem Biophys Res Commun. 2008;373:659-64 pubmed publisher
    ..Here we report that the Arabidopsis SET domain group 8 (SDG8) protein is a histone H3 methyltransferase involved in regulating shoot branching...
  4. Kim S, He Y, Jacob Y, Noh Y, Michaels S, Amasino R. Establishment of the vernalization-responsive, winter-annual habit in Arabidopsis requires a putative histone H3 methyl transferase. Plant Cell. 2005;17:3301-10 pubmed
    ..Lesions in this methyl transferase, EARLY FLOWERING IN SHORT DAYS (EFS), result in reduced levels of histone H3 Lys 4 trimethylation in FLC chromatin...
  5. Cazzonelli C, Roberts A, Carmody M, Pogson B. Transcriptional control of SET DOMAIN GROUP 8 and CAROTENOID ISOMERASE during Arabidopsis development. Mol Plant. 2010;3:174-91 pubmed publisher
    ..Here, we show how the branch point can be regulated by the chromatin-modifying histone methyltransferase, Set Domain Group 8 (SDG8) targeting the carotenoid isomerase (CRTISO)...
  6. Xu L, Zhao Z, Dong A, Soubigou Taconnat L, Renou J, Steinmetz A, et al. Di- and tri- but not monomethylation on histone H3 lysine 36 marks active transcription of genes involved in flowering time regulation and other processes in Arabidopsis thaliana. Mol Cell Biol. 2008;28:1348-60 pubmed
    ..The SET2 homologs SDG8 and SDG26 each can methylate oligonucleosomes in vitro, and both proteins are localized in the nucleus...
  7. Wang X, Chen J, Xie Z, Liu S, Nolan T, Ye H, et al. Histone lysine methyltransferase SDG8 is involved in brassinosteroid-regulated gene expression in Arabidopsis thaliana. Mol Plant. 2014;7:1303-1315 pubmed publisher
    ..Here we report that histone lysine methyltransferase SDG8, implicated in histone 3 lysine 36 di- and trimethylation (H3K36me2 and me3), is involved in BR-regulated gene ..
  8. Liu B, Berr A, Chang C, Liu C, Shen W, Ruan Y. Interplay of the histone methyltransferases SDG8 and SDG26 in the regulation of transcription and plant flowering and development. Biochim Biophys Acta. 2016;1859:581-90 pubmed publisher
    ..powerful genetic tool in Arabidopsis, we here investigate the interplay between two close HKMT homologues, SET DOMAIN GROUP 8 (SDG8) and SDG26, in regulating transcription and plant growth and development...
  9. Lee N, Kang H, Lee D, Choi G. A histone methyltransferase inhibits seed germination by increasing PIF1 mRNA expression in imbibed seeds. Plant J. 2014;78:282-93 pubmed publisher
    ..Here we show that mutation of the early flowering in short days (EFS) gene, encoding an H3K4 and H3K36 methyltransferase, decreases the level of H3K36me2 and H3K36me3 ..
  10. Sui P, Jin J, Ye S, Mu C, Gao J, Feng H, et al. H3K36 methylation is critical for brassinosteroid-regulated plant growth and development in rice. Plant J. 2012;70:340-7 pubmed publisher
    ..Taken together, our data indicate that SDG725-mediated H3K36 methylation modulates brassinosteroid-related gene expression, playing an important role in rice plant growth and development. ..

Detail Information

Publications19

  1. Cazzonelli C, Cuttriss A, Cossetto S, Pye W, Crisp P, Whelan J, et al. Regulation of carotenoid composition and shoot branching in Arabidopsis by a chromatin modifying histone methyltransferase, SDG8. Plant Cell. 2009;21:39-53 pubmed publisher
    ..We report the cloning of the CAROTENOID CHLOROPLAST REGULATORY1 (CCR1) gene...
  2. Grini P, Thorstensen T, Alm V, Vizcay Barrena G, Windju S, Jørstad T, et al. The ASH1 HOMOLOG 2 (ASHH2) histone H3 methyltransferase is required for ovule and anther development in Arabidopsis. PLoS ONE. 2009;4:e7817 pubmed publisher
    ..The Arabidopsis ASH1 HOMOLOG 2 (ASHH2) protein (also called SDG8, EFS and CCR1) has been suggested to methylate H3K4 and/or H3K36 and is ..
  3. Dong G, Ma D, Li J. The histone methyltransferase SDG8 regulates shoot branching in Arabidopsis. Biochem Biophys Res Commun. 2008;373:659-64 pubmed publisher
    ..Here we report that the Arabidopsis SET domain group 8 (SDG8) protein is a histone H3 methyltransferase involved in regulating shoot branching...
  4. Kim S, He Y, Jacob Y, Noh Y, Michaels S, Amasino R. Establishment of the vernalization-responsive, winter-annual habit in Arabidopsis requires a putative histone H3 methyl transferase. Plant Cell. 2005;17:3301-10 pubmed
    ..Lesions in this methyl transferase, EARLY FLOWERING IN SHORT DAYS (EFS), result in reduced levels of histone H3 Lys 4 trimethylation in FLC chromatin...
  5. Cazzonelli C, Roberts A, Carmody M, Pogson B. Transcriptional control of SET DOMAIN GROUP 8 and CAROTENOID ISOMERASE during Arabidopsis development. Mol Plant. 2010;3:174-91 pubmed publisher
    ..Here, we show how the branch point can be regulated by the chromatin-modifying histone methyltransferase, Set Domain Group 8 (SDG8) targeting the carotenoid isomerase (CRTISO)...
  6. Xu L, Zhao Z, Dong A, Soubigou Taconnat L, Renou J, Steinmetz A, et al. Di- and tri- but not monomethylation on histone H3 lysine 36 marks active transcription of genes involved in flowering time regulation and other processes in Arabidopsis thaliana. Mol Cell Biol. 2008;28:1348-60 pubmed
    ..The SET2 homologs SDG8 and SDG26 each can methylate oligonucleosomes in vitro, and both proteins are localized in the nucleus...
  7. Wang X, Chen J, Xie Z, Liu S, Nolan T, Ye H, et al. Histone lysine methyltransferase SDG8 is involved in brassinosteroid-regulated gene expression in Arabidopsis thaliana. Mol Plant. 2014;7:1303-1315 pubmed publisher
    ..Here we report that histone lysine methyltransferase SDG8, implicated in histone 3 lysine 36 di- and trimethylation (H3K36me2 and me3), is involved in BR-regulated gene ..
  8. Liu B, Berr A, Chang C, Liu C, Shen W, Ruan Y. Interplay of the histone methyltransferases SDG8 and SDG26 in the regulation of transcription and plant flowering and development. Biochim Biophys Acta. 2016;1859:581-90 pubmed publisher
    ..powerful genetic tool in Arabidopsis, we here investigate the interplay between two close HKMT homologues, SET DOMAIN GROUP 8 (SDG8) and SDG26, in regulating transcription and plant growth and development...
  9. Lee N, Kang H, Lee D, Choi G. A histone methyltransferase inhibits seed germination by increasing PIF1 mRNA expression in imbibed seeds. Plant J. 2014;78:282-93 pubmed publisher
    ..Here we show that mutation of the early flowering in short days (EFS) gene, encoding an H3K4 and H3K36 methyltransferase, decreases the level of H3K36me2 and H3K36me3 ..
  10. Sui P, Jin J, Ye S, Mu C, Gao J, Feng H, et al. H3K36 methylation is critical for brassinosteroid-regulated plant growth and development in rice. Plant J. 2012;70:340-7 pubmed publisher
    ..Taken together, our data indicate that SDG725-mediated H3K36 methylation modulates brassinosteroid-related gene expression, playing an important role in rice plant growth and development. ..
  11. Palma K, Thorgrimsen S, Malinovsky F, Fiil B, Nielsen H, Brodersen P, et al. Autoimmunity in Arabidopsis acd11 is mediated by epigenetic regulation of an immune receptor. PLoS Pathog. 2010;6:e1001137 pubmed publisher
    ..In a screen for lazarus (laz) mutants that suppress acd11 death we identified two genes, LAZ2 and LAZ5...
  12. Fromm M, Avramova Z. ATX1/AtCOMPASS and the H3K4me3 marks: how do they activate Arabidopsis genes?. Curr Opin Plant Biol. 2014;21:75-82 pubmed publisher
  13. Soppe W, Bentsink L, Koornneef M. The early-flowering mutant efs is involved in the autonomous promotion pathway of Arabidopsis thaliana. Development. 1999;126:4763-70 pubmed
    ..for early flowering, after mutagenesis of the late-flowering fwa mutant of Arabidopsis thaliana, the early flowering in short days (efs) mutant was identified...
  14. Valencia Morales M, Camas Reyes J, Cabrera Ponce J, Alvarez Venegas R. The Arabidopsis thaliana SET-domain-containing protein ASHH1/SDG26 interacts with itself and with distinct histone lysine methyltransferases. J Plant Res. 2012;125:679-92 pubmed publisher
    ..sequences from two distinct histone lysine methyltransferases, the ARABIDOPSIS HOMOLOG OF TRITHORAX-1 (ATX1) and ASHH2 proteins...
  15. Hoppmann V, Thorstensen T, Kristiansen P, Veiseth S, Rahman M, Finne K, et al. The CW domain, a new histone recognition module in chromatin proteins. EMBO J. 2011;30:1939-52 pubmed publisher
    ..The solution structure of the CW domain of the Arabidopsis ASH1 HOMOLOG2 (ASHH2) histone methyltransferase provides insight into how different CW domains can distinguish different methylated ..
  16. Elrouby N, Bonequi M, Porri A, Coupland G. Identification of Arabidopsis SUMO-interacting proteins that regulate chromatin activity and developmental transitions. Proc Natl Acad Sci U S A. 2013;110:19956-61 pubmed publisher
    ..It reduces protein levels of CYCLING DOF FACTOR 2, hence increasing transcript levels of CONSTANS and promoting flowering through the photoperiodic pathway. ..
  17. Tang X, Lim M, Pelletier J, Tang M, Nguyen V, Keller W, et al. Synergistic repression of the embryonic programme by SET DOMAIN GROUP 8 and EMBRYONIC FLOWER 2 in Arabidopsis seedlings. J Exp Bot. 2012;63:1391-404 pubmed publisher
    ..Here, it is shown that mutations affecting SDG8 (SET DOMAIN GROUP 8), a putative histone methyltransferase, cause ectopic expression of a subset of maturation genes in leaves...
  18. Berr A, McCallum E, Alioua A, Heintz D, Heitz T, Shen W. Arabidopsis histone methyltransferase SET DOMAIN GROUP8 mediates induction of the jasmonate/ethylene pathway genes in plant defense response to necrotrophic fungi. Plant Physiol. 2010;154:1403-14 pubmed publisher
    ..idea, we demonstrate here that the Arabidopsis (Arabidopsis thaliana) histone methyltransferase SET DOMAIN GROUP8 (SDG8) plays a crucial role in plant defense against fungal pathogens by regulating a subset of genes within the jasmonic ..
  19. Lee S, Fu F, Xu S, Lee S, Yun D, Mengiste T. Global Regulation of Plant Immunity by Histone Lysine Methyl Transferases. Plant Cell. 2016;28:1640-61 pubmed publisher
    ..We showed that the Arabidopsis thaliana histone methyl transferases SET DOMAIN GROUP8 (SDG8) and SDG25 regulate pep1-, flg22-, and effector-triggered immunity as well as systemic acquired resistance...