Gene Symbol: DPE2
Description: disproportionating enzyme 2
Alias: T20B5.4, T20B5_4, disproportionating enzyme 2, disproportionating enzyme 2
Species: thale cress

Top Publications

  1. Fettke J, Eckermann N, Tiessen A, Geigenberger P, Steup M. Identification, subcellular localization and biochemical characterization of water-soluble heteroglycans (SHG) in leaves of Arabidopsis thaliana L.: distinct SHG reside in the cytosol and in the apoplast. Plant J. 2005;43:568-85 pubmed
    ..As revealed by in vivo labeling experiments using 14CO2 carbon fluxes into subfraction I and II differed. Furthermore, in leaves the pool size of subfraction I varied during the light-dark regime. ..
  2. Lu Y, Steichen J, Weise S, Sharkey T. Cellular and organ level localization of maltose in maltose-excess Arabidopsis mutants. Planta. 2006;224:935-43 pubmed
    ..Plants that lack either the chloroplast maltose transporter or disproportionating enzyme 2 (DPE2, EC have excess maltose in leaves...
  3. Yazdanbakhsh N, Fisahn J. Mutations in leaf starch metabolism modulate the diurnal root growth profiles of Arabidopsis thaliana. Plant Signal Behav. 2011;6:995-8 pubmed
    ..imaging was performed to quantify the growth kinetics of Arabidopsis wild-type as well as pgm, sex1, mex1, dpe1 and dpe2 starch metabolism mutants grown in three different photoperiods...
  4. Chia T, Thorneycroft D, Chapple A, Messerli G, Chen J, Zeeman S, et al. A cytosolic glucosyltransferase is required for conversion of starch to sucrose in Arabidopsis leaves at night. Plant J. 2004;37:853-63 pubmed
    ..we characterised plants with mutations in a gene encoding a putative glucanotransferase (disproportionating enzyme; DPE2), a protein similar to the maltase Q (MalQ) gene product involved in maltose metabolism in bacteria...
  5. Malinova I, Fettke J. Reduced starch granule number per chloroplast in the dpe2/phs1 mutant is dependent on initiation of starch degradation. PLoS ONE. 2017;12:e0187985 pubmed publisher
    An Arabidopsis double knock-out mutant lacking cytosolic disproportionating enzyme 2 (DPE2) and the plastidial phosphorylase (PHS1) revealed a dwarf-growth phenotype, reduced starch content, an uneven distribution of starch within the ..
  6. Smith A, Zeeman S, Smith S. Starch degradation. Annu Rev Plant Biol. 2005;56:73-98 pubmed
    ..We discuss the differences in relation to the biology of each system. ..
  7. Malinova I, Mahlow S, Alseekh S, Orawetz T, Fernie A, Baumann O, et al. Double knockout mutants of Arabidopsis grown under normal conditions reveal that the plastidial phosphorylase isozyme participates in transitory starch metabolism. Plant Physiol. 2014;164:907-21 pubmed publisher
    ..starch-related single-knockout lines lacking either the cytosolic transglucosidase (also designated as disproportionating enzyme 2, DPE2) or the maltose transporter (MEX1), the activity of the plastidial phosphorylase isozyme (PHS1) ..
  8. Lu Y, Sharkey T. The role of amylomaltase in maltose metabolism in the cytosol of photosynthetic cells. Planta. 2004;218:466-73 pubmed
    ..were identified in which the gene encoding a putative amylomaltase enzyme [ disproportionating enzyme 2, DPE2 (DPE1 refers to the plastid version of this enzyme)] was disrupted by a T-DNA insertion...
  9. Fettke J, Chia T, Eckermann N, Smith A, Steup M. A transglucosidase necessary for starch degradation and maltose metabolism in leaves at night acts on cytosolic heteroglycans (SHG). Plant J. 2006;46:668-84 pubmed
    The recently characterized cytosolic transglucosidase DPE2 (EC is essential for the cytosolic metabolism of maltose, an intermediate on the pathway by which starch is converted to sucrose at night...

More Information


  1. Lu Y, Steichen J, Yao J, Sharkey T. The role of cytosolic alpha-glucan phosphorylase in maltose metabolism and the comparison of amylomaltase in Arabidopsis and Escherichia coli. Plant Physiol. 2006;142:878-89 pubmed
    ..of MalQ and MalP in the cytosol of Arabidopsis (Arabidopsis thaliana) were proposed as disproportionating enzyme (DPE2, At2g40840) and alpha-glucan phosphorylase (AtPHS2, At3g46970)...