Gene Symbol: DMS3
Description: defective in meristem silencing 3
Alias: DEFECTIVE IN MERISTEM SILENCING 3, IDN1, INVOLVED IN DE NOVO 1, defective in meristem silencing 3
Species: thale cress
Wierzbicki A, Ream T, Haag J, Pikaard C. RNA polymerase V transcription guides ARGONAUTE4 to chromatin. Nat Genet. 2009;41:630-4 pubmed publisher
..We further show that DEFECTIVE IN MERISTEM SILENCING3 (DMS3), a structural maintenance of chromosomes (SMC) hinge-domain protein, functions in the assembly of Pol V ..
Law J, Ausin I, Johnson L, Vashisht A, Zhu J, Wohlschlegel J, et al
. A protein complex required for polymerase V transcripts and RNA- directed DNA methylation in Arabidopsis. Curr Biol. 2010;20:951-6 pubmed publisher
..purification of two known RdDM components, DEFECTIVE IN RNA-DIRECTED DNA METHYLATION 1 (DRD1) and DEFECTIVE IN MERISTEM SILENCING 3 (DMS3), we found that they copurify with each other and with a novel protein, RNA-DIRECTED DNA ..
Zhong X, Hale C, Law J, Johnson L, Feng S, Tu A, et al
. DDR complex facilitates global association of RNA polymerase V to promoters and evolutionarily young transposons. Nat Struct Mol Biol. 2012;19:870-5 pubmed publisher
..Furthermore, these findings suggest a role for Pol V and RNA-directed DNA methylation in genome surveillance and in responding to genome evolution. ..
Lorkovic Z, Naumann U, Matzke A, Matzke M. Involvement of a GHKL ATPase in RNA-directed DNA methylation in Arabidopsis thaliana. Curr Biol. 2012;22:933-8 pubmed publisher
..DMS11 interacts physically with another RdDM component, DMS3, an unusual structural maintenance of chromosomes (SMC) hinge domain-containing protein that lacks the ATPase ..
Kanno T, Bucher E, Daxinger L, Huettel B, Böhmdorfer G, Gregor W, et al
. A structural-maintenance-of-chromosomes hinge domain-containing protein is required for RNA-directed DNA methylation. Nat Genet. 2008;40:670-5 pubmed publisher
..Additionally, we identified a previously unknown gene DMS3 (At3g49250), encoding a protein similar to the hinge-domain region of structural maintenance of chromosomes (SMC) ..
Ausin I, Mockler T, Chory J, Jacobsen S. IDN1 and IDN2 are required for de novo DNA methylation in Arabidopsis thaliana. Nat Struct Mol Biol. 2009;16:1325-7 pubmed publisher
..IDN1 encodes DMS3, an SMC-related protein, and IDN2 encodes a previously unknown double-stranded RNA-binding protein with homology to ..
Zhong X, Hale C, Nguyen M, Ausin I, Groth M, Hetzel J, et al
. Domains rearranged methyltransferase3 controls DNA methylation and regulates RNA polymerase V transcript abundance in Arabidopsis. Proc Natl Acad Sci U S A. 2015;112:911-6 pubmed publisher
..This work sheds further light on the mechanism by which long noncoding RNAs facilitate RNA-directed DNA methylation. ..
Bang W, Kim S, Jeong I, Koiwa H, Bahk J. The C-terminal region (640-967) of Arabidopsis CPL1 interacts with the abiotic stress- and ABA-responsive transcription factors. Biochem Biophys Res Commun. 2008;372:907-12 pubmed publisher
..GFP-fusion analysis indicated that AtMYB3 localized in nuclei-like CPL1, and its expression is induced by abiotic stress and ABA treatment. These results suggest that AtMYB3 function in abiotic stress signaling in concert with CPL1. ..
Sasaki T, Lorkovic Z, Liang S, Matzke A, Matzke M. The ability to form homodimers is essential for RDM1 to function in RNA-directed DNA methylation. PLoS ONE. 2014;9:e88190 pubmed publisher
..DRD1) and the structural-maintenance-of-chromosomes solo hinge protein DEFECTIVE IN MERISTEM SILENCING3 (DMS3) to form the DDR complex, which facilitates synthesis of Pol V scaffold transcripts...