Gene Symbol: DL3
Description: dynamin-like 3
Alias: ADL3, CF1, DRP2B, DYNAMIN-LIKE 3, Dynamin related protein 2B, T30E16.17, T30E16_17, dynamin-like 3, dynamin-like 3
Species: thale cress

Top Publications

  1. Backues S, Korasick D, Heese A, Bednarek S. The Arabidopsis dynamin-related protein2 family is essential for gametophyte development. Plant Cell. 2010;22:3218-31 pubmed publisher
    ..Gametophytes lacking both DRP2A and DRP2B were inviable, arresting prior to the first mitotic division in both male and female gametogenesis...
  2. Fujimoto M, Arimura S, Nakazono M, Tsutsumi N. Arabidopsis dynamin-related protein DRP2B is co-localized with DRP1A on the leading edge of the forming cell plate. Plant Cell Rep. 2008;27:1581-6 pubmed publisher
    The Arabidopsis genome has six families of dynamin-related proteins. One of these families includes DRP2A and DRP2B. The domain structures of proteins of this family are most similar to those of the animal endocytosis protein, dynamin...
  3. Taylor N. A role for Arabidopsis dynamin related proteins DRP2A/B in endocytosis; DRP2 function is essential for plant growth. Plant Mol Biol. 2011;76:117-29 pubmed publisher
    ..obvious phenotypes but double mutants could be recovered as gametophytes carrying mutant copies of both DRP2A and DRP2B were not transmitted to the next generation...
  4. Fujimoto M, Arimura S, Ueda T, Takanashi H, Hayashi Y, Nakano A, et al. Arabidopsis dynamin-related proteins DRP2B and DRP1A participate together in clathrin-coated vesicle formation during endocytosis. Proc Natl Acad Sci U S A. 2010;107:6094-9 pubmed publisher
    ..endocytic CCV formation in plant cells, we compared the behaviors of two structurally different Arabidopsis DRPs, DRP2B and DRP1A, with those of the clathrin light chain (CLC), a marker of CCVs, at the plasma membrane by variable ..
  5. Stanislas T, Hüser A, Barbosa I, Kiefer C, Brackmann K, Pietra S, et al. Arabidopsis D6PK is a lipid domain-dependent mediator of root epidermal planar polarity. Nat Plants. 2015;1:15162 pubmed publisher
    ..ROP) 2 and 6, phosphatidylinositol-4-phosphate 5-kinase 3 (PIP5K3), DYNAMIN-RELATED PROTEIN (DRP) 1A and DRP2B accumulate in a sterol-enriched, polar membrane domain during root hair initiation...
  6. Mikami K, Iuchi S, Yamaguchi Shinozaki K, Shinozaki K. A novel Arabidopsis thaliana dynamin-like protein containing the pleckstrin homology domain. J Exp Bot. 2000;51:317-8 pubmed
    A full-length cDNA encoding a novel type of plant dynamin-like protein, ADL3, was isolated from Arabidopsis thaliana...
  7. Atmodjo M, Sakuragi Y, Zhu X, Burrell A, Mohanty S, Atwood J, et al. Galacturonosyltransferase (GAUT)1 and GAUT7 are the core of a plant cell wall pectin biosynthetic homogalacturonan:galacturonosyltransferase complex. Proc Natl Acad Sci U S A. 2011;108:20225-30 pubmed publisher
  8. Huang J, Fujimoto M, Fujiwara M, Fukao Y, Arimura S, Tsutsumi N. Arabidopsis dynamin-related proteins, DRP2A and DRP2B, function coordinately in post-Golgi trafficking. Biochem Biophys Res Commun. 2015;456:238-44 pubmed publisher
    ..In Arabidopsis thaliana, two paralogous land plant-specific type DRPs, DRP2A and DRP2B, are thought to participate in the regulation of post-Golgi trafficking...
  9. Smith J, Leslie M, Robinson S, Korasick D, Zhang T, Backues S, et al. Loss of Arabidopsis thaliana Dynamin-Related Protein 2B reveals separation of innate immune signaling pathways. PLoS Pathog. 2014;10:e1004578 pubmed publisher
    ..Here we demonstrate that Arabidopsis thaliana Dynamin-Related Protein 2B (DRP2B), which has been previously implicated in constitutive clathrin-mediated endocytosis (CME), functions in responses ..

More Information


  1. Chaparro Garcia A, Schwizer S, Sklenar J, Yoshida K, Petre B, Bos J, et al. Phytophthora infestans RXLR-WY Effector AVR3a Associates with Dynamin-Related Protein 2 Required for Endocytosis of the Plant Pattern Recognition Receptor FLS2. PLoS ONE. 2015;10:e0137071 pubmed publisher
    ..We conclude that AVR3a is a multifunctional effector that can suppress BAK1/SERK3-mediated immunity through at least two different pathways. ..