Genomes and Genes
Gene Symbol: CYT1
Description: Glucose-1-phosphate adenylyltransferase family protein
Alias: CYTOKINESIS DEFECTIVE 1, EMB101, EMBRYO DEFECTIVE 101, GDP-MANNOSE PYROPHOSPHORYLASE 1, GMP1, SENSITIVE TO OZONE 1, SOZ1, T5I7.7, T5I7_7, VITAMIN C DEFECTIVE 1, VTC1, Glucose-1-phosphate adenylyltransferase family protein
Species: thale cress
- Barth C, Gouzd Z, Steele H, Imperio R. A mutation in GDP-mannose pyrophosphorylase causes conditional hypersensitivity to ammonium, resulting in Arabidopsis root growth inhibition, altered ammonium metabolism, and hormone homeostasis. J Exp Bot. 2010;61:379-94 pubmed publisher..in the quiescent centre of the root, it was hypothesized that the AA-deficient Arabidopsis thaliana mutants vtc1-1, vtc2-1, vtc3-1, and vtc4-1 have altered root growth...
- Li S, Wang J, Yu Y, Wang F, Dong J, Huang R. D27E mutation of VTC1 impairs the interaction with CSN5B and enhances ascorbic acid biosynthesis and seedling growth in Arabidopsis. Plant Mol Biol. 2016;92:473-482 pubmedOur previous investigation revealed that GDP-Man pyrophosphorylase (VTC1), a vital ascorbic acid (AsA) biosynthesis enzyme, could be degraded through interaction with the photomorphogenic factor COP9 signalosome subunit 5B (CSN5B) in the ..
- Sasaki Sekimoto Y, Taki N, Obayashi T, Aono M, Matsumoto F, Sakurai N, et al. Coordinated activation of metabolic pathways for antioxidants and defence compounds by jasmonates and their roles in stress tolerance in Arabidopsis. Plant J. 2005;44:653-68 pubmed..Compared with the wild type, opr3 mutants were more sensitive to O3 exposure. These results suggest that the coordinated activation of the metabolic pathways mediated by jasmonates provides resistance to environmental stresses. ..
- Zhao S, Liu L. Expression and crystallographic studies of the Arabidopsis thaliana GDP-D-mannose pyrophosphorylase VTC1. Acta Crystallogr F Struct Biol Commun. 2016;72:795-798 pubmed..This enzyme is a key regulatory target in AsA biosynthesis and is encoded by VITAMIN C DEFECTIVE 1 (VTC1) in the Arabidopsis thaliana genome. Here, recombinant VTC1 was expressed, purified and crystallized...