CRY1

Summary

Gene Symbol: CRY1
Description: cryptochrome 1
Alias: ATCRY1, BLU1, BLUE LIGHT UNINHIBITED 1, CRYPTOCHROME 1 APOPROTEIN (BLUE LIGHT PHOTORECEPTOR, ELONGATED HYPOCOTYL 4, HY4, OOP2, OUT OF PHASE 2, T3H13.14, T3H13_14, cryptochrome 1, cryptochrome 1
Species: thale cress
Products:     CRY1

Top Publications

  1. Lin C, Ahmad M, Cashmore A. Arabidopsis cryptochrome 1 is a soluble protein mediating blue light-dependent regulation of plant growth and development. Plant J. 1996;10:893-902 pubmed
    b>Cryptochrome 1 (CRY1) is a flavin-type blue type receptor of Arabidopsis thaliana which mediates inhibition of hypocotyl elongation...
  2. Kang B, Grancher N, Koyffmann V, Lardemer D, Burney S, Ahmad M. Multiple interactions between cryptochrome and phototropin blue-light signalling pathways in Arabidopsis thaliana. Planta. 2008;227:1091-9 pubmed publisher
    ..These two classes of photoreceptor thereby reciprocally modulate their overall responsivity to blue light through multiple forms of interaction. ..
  3. Sellaro R, Crepy M, Trupkin S, Karayekov E, Buchovsky A, Rossi C, et al. Cryptochrome as a sensor of the blue/green ratio of natural radiation in Arabidopsis. Plant Physiol. 2010;154:401-9 pubmed publisher
    ..The impact of blue/green ratio on cryptochrome-mediated inhibition of hypocotyl growth was at least as large as that of irradiance. We conclude that cryptochrome is a sensor of blue irradiance and blue/green ratio. ..
  4. Neff M, Chory J. Genetic interactions between phytochrome A, phytochrome B, and cryptochrome 1 during Arabidopsis development. Plant Physiol. 1998;118:27-35 pubmed
    ..phyA was the major photoreceptor/effector for most far-red-light responses, although phyB and cry1 modulated anthocyanin accumulation in a phyA-dependent manner...
  5. Gu N, Zhang Y, Yang H. Substitution of a conserved glycine in the PHR domain of Arabidopsis cryptochrome 1 confers a constitutive light response. Mol Plant. 2012;5:85-97 pubmed publisher
    ..The signaling mechanism of Arabidopsis CRYs (CRY1 and CRY2) involves direct CRY-COP1 interaction...
  6. Hong S, Kim H, Ryu J, Choi H, Jeong S, Shin J, et al. CRY1 inhibits COP1-mediated degradation of BIT1, a MYB transcription factor, to activate blue light-dependent gene expression in Arabidopsis. Plant J. 2008;55:361-71 pubmed publisher
    ..assay showed that BIT1 regulates promoter activity of PsbS in a blue light-dependent manner and that it requires CRY1 for activation of the PsbS promoter...
  7. Lasceve G, Leymarie J, Olney M, Liscum E, Christie J, Vavasseur A, et al. Arabidopsis contains at least four independent blue-light-activated signal transduction pathways. Plant Physiol. 1999;120:605-14 pubmed
    ..The stomatal responses of light-grown mutant plants (cry1, cry2, nph1, nph3, nph4, cry1cry2, and nph1cry1) did not differ significantly from those of their wild-type ..
  8. Zeugner A, Byrdin M, Bouly J, Bakrim N, Giovani B, Brettel K, et al. Light-induced electron transfer in Arabidopsis cryptochrome-1 correlates with in vivo function. J Biol Chem. 2005;280:19437-40 pubmed
    ..These data support the possibility that light-induced flavin reduction via the tryptophan chain is the primary step in the signaling pathway of plant cryptochrome. ..
  9. Yang H, Tang R, Cashmore A. The signaling mechanism of Arabidopsis CRY1 involves direct interaction with COP1. Plant Cell. 2001;13:2573-87 pubmed
    ..Here we show that Arabidopsis cryptochrome 1 (CRY1) and its C-terminal domain (CCT1) interacted strongly with the COP1 protein...
  10. Jarillo J, Capel J, Tang R, Yang H, Alonso J, Ecker J, et al. An Arabidopsis circadian clock component interacts with both CRY1 and phyB. Nature. 2001;410:487-90 pubmed
    ..Both yeast two-hybrid and in vitro binding studies show that there is a physical interaction between ADO1 and the photoreceptors CRY1 and phyB. We propose that ADO1 is an important component of the Arabidopsis circadian system.

Detail Information

Publications67

  1. Lin C, Ahmad M, Cashmore A. Arabidopsis cryptochrome 1 is a soluble protein mediating blue light-dependent regulation of plant growth and development. Plant J. 1996;10:893-902 pubmed
    b>Cryptochrome 1 (CRY1) is a flavin-type blue type receptor of Arabidopsis thaliana which mediates inhibition of hypocotyl elongation...
  2. Kang B, Grancher N, Koyffmann V, Lardemer D, Burney S, Ahmad M. Multiple interactions between cryptochrome and phototropin blue-light signalling pathways in Arabidopsis thaliana. Planta. 2008;227:1091-9 pubmed publisher
    ..These two classes of photoreceptor thereby reciprocally modulate their overall responsivity to blue light through multiple forms of interaction. ..
  3. Sellaro R, Crepy M, Trupkin S, Karayekov E, Buchovsky A, Rossi C, et al. Cryptochrome as a sensor of the blue/green ratio of natural radiation in Arabidopsis. Plant Physiol. 2010;154:401-9 pubmed publisher
    ..The impact of blue/green ratio on cryptochrome-mediated inhibition of hypocotyl growth was at least as large as that of irradiance. We conclude that cryptochrome is a sensor of blue irradiance and blue/green ratio. ..
  4. Neff M, Chory J. Genetic interactions between phytochrome A, phytochrome B, and cryptochrome 1 during Arabidopsis development. Plant Physiol. 1998;118:27-35 pubmed
    ..phyA was the major photoreceptor/effector for most far-red-light responses, although phyB and cry1 modulated anthocyanin accumulation in a phyA-dependent manner...
  5. Gu N, Zhang Y, Yang H. Substitution of a conserved glycine in the PHR domain of Arabidopsis cryptochrome 1 confers a constitutive light response. Mol Plant. 2012;5:85-97 pubmed publisher
    ..The signaling mechanism of Arabidopsis CRYs (CRY1 and CRY2) involves direct CRY-COP1 interaction...
  6. Hong S, Kim H, Ryu J, Choi H, Jeong S, Shin J, et al. CRY1 inhibits COP1-mediated degradation of BIT1, a MYB transcription factor, to activate blue light-dependent gene expression in Arabidopsis. Plant J. 2008;55:361-71 pubmed publisher
    ..assay showed that BIT1 regulates promoter activity of PsbS in a blue light-dependent manner and that it requires CRY1 for activation of the PsbS promoter...
  7. Lasceve G, Leymarie J, Olney M, Liscum E, Christie J, Vavasseur A, et al. Arabidopsis contains at least four independent blue-light-activated signal transduction pathways. Plant Physiol. 1999;120:605-14 pubmed
    ..The stomatal responses of light-grown mutant plants (cry1, cry2, nph1, nph3, nph4, cry1cry2, and nph1cry1) did not differ significantly from those of their wild-type ..
  8. Zeugner A, Byrdin M, Bouly J, Bakrim N, Giovani B, Brettel K, et al. Light-induced electron transfer in Arabidopsis cryptochrome-1 correlates with in vivo function. J Biol Chem. 2005;280:19437-40 pubmed
    ..These data support the possibility that light-induced flavin reduction via the tryptophan chain is the primary step in the signaling pathway of plant cryptochrome. ..
  9. Yang H, Tang R, Cashmore A. The signaling mechanism of Arabidopsis CRY1 involves direct interaction with COP1. Plant Cell. 2001;13:2573-87 pubmed
    ..Here we show that Arabidopsis cryptochrome 1 (CRY1) and its C-terminal domain (CCT1) interacted strongly with the COP1 protein...
  10. Jarillo J, Capel J, Tang R, Yang H, Alonso J, Ecker J, et al. An Arabidopsis circadian clock component interacts with both CRY1 and phyB. Nature. 2001;410:487-90 pubmed
    ..Both yeast two-hybrid and in vitro binding studies show that there is a physical interaction between ADO1 and the photoreceptors CRY1 and phyB. We propose that ADO1 is an important component of the Arabidopsis circadian system.
  11. Millenaar F, van Zanten M, Cox M, Pierik R, Voesenek L, Peeters A. Differential petiole growth in Arabidopsis thaliana: photocontrol and hormonal regulation. New Phytol. 2009;184:141-52 pubmed publisher
  12. Canamero R, Bakrim N, Bouly J, Garay A, Dudkin E, Habricot Y, et al. Cryptochrome photoreceptors cry1 and cry2 antagonistically regulate primary root elongation in Arabidopsis thaliana. Planta. 2006;224:995-1003 pubmed
    ..Here we report the effect of cry1 and cry2 blue light receptors on primary root growth in Arabidopsis thaliana seedlings, through analysis of both ..
  13. Mao J, Zhang Y, Sang Y, Li Q, Yang H. From The Cover: A role for Arabidopsis cryptochromes and COP1 in the regulation of stomatal opening. Proc Natl Acad Sci U S A. 2005;102:12270-5 pubmed
    ..Arabidopsis CRY (CRY1 and CRY2) functions through negatively regulating constitutive photomorphogenic (COP) 1, a repressor of ..
  14. Bouly J, Giovani B, Djamei A, Mueller M, Zeugner A, Dudkin E, et al. Novel ATP-binding and autophosphorylation activity associated with Arabidopsis and human cryptochrome-1. Eur J Biochem. 2003;270:2921-8 pubmed
    ..Here, we report a novel ATP binding and autophosphorylation activity associated with Arabidopsis cry1 protein purified from a baculovirus expression system...
  15. Wang H, Ma L, Li J, Zhao H, Deng X. Direct interaction of Arabidopsis cryptochromes with COP1 in light control development. Science. 2001;294:154-8 pubmed
    ..Arabidopsis has two related cryptochromes (cry1 and cry2) mediating various blue/ultraviolet-A light responses...
  16. Cashmore A, Jarillo J, Wu Y, Liu D. Cryptochromes: blue light receptors for plants and animals. Science. 1999;284:760-5 pubmed
    ..This process of repeated evolution may have coincided with the origin in animals of a modified circadian clock based on the PERIOD, TIMELESS, CLOCK, and CYCLE proteins. ..
  17. Toth R, Kevei E, Hall A, Millar A, Nagy F, Kozma Bognar L. Circadian clock-regulated expression of phytochrome and cryptochrome genes in Arabidopsis. Plant Physiol. 2001;127:1607-16 pubmed
    ..and long-term light-regulated expression patterns of the Arabidopsis phytochrome (PHYA to PHYE) and cryptochrome (CRY1 and CRY2) promoters fused to the luciferase (LUC(+)) reporter gene...
  18. Bouly J, Schleicher E, Dionisio Sese M, Vandenbussche F, Van Der Straeten D, Bakrim N, et al. Cryptochrome blue light photoreceptors are activated through interconversion of flavin redox states. J Biol Chem. 2007;282:9383-91 pubmed
    ..We further characterize light-dependent changes in the cryptochrome1 (cry1) protein in living cells, which match photoreduction of the purified cry1 in vitro...
  19. Ahmad M, Jarillo J, Smirnova O, Cashmore A. The CRY1 blue light photoreceptor of Arabidopsis interacts with phytochrome A in vitro. Mol Cell. 1998;1:939-48 pubmed
    ..Here, we demonstrate in vitro, using purified recombinant photoreceptors, that Arabidopsis CRY1 and CRY2 (cryptochrome) are substrates for phosphorylation by a phytochrome A-associated kinase activity...
  20. Hughes R, Vrana J, Song J, Tucker C. Light-dependent, dark-promoted interaction between Arabidopsis cryptochrome 1 and phytochrome B proteins. J Biol Chem. 2012;287:22165-72 pubmed publisher
    ..with critical roles in photomorphogenesis are phytochrome B (phyB), a red/far-red absorbing photoreceptor, and cryptochrome 1 (CRY1), a UV-A/blue photoreceptor...
  21. Boccalandro H, Giordano C, Ploschuk E, Piccoli P, Bottini R, Casal J. Phototropins but not cryptochromes mediate the blue light-specific promotion of stomatal conductance, while both enhance photosynthesis and transpiration under full sunlight. Plant Physiol. 2012;158:1475-84 pubmed publisher
    ..Arabidopsis thaliana) mutants lacking either phototropins 1 and 2 (phot1 and phot2) or cryptochromes 1 and 2 (cry1 and cry2) exposed to a background of red light show severely impaired stomatal opening responses to blue light...
  22. Gao J, Wang X, Zhang M, Bian M, Deng W, Zuo Z, et al. Trp triad-dependent rapid photoreduction is not required for the function of Arabidopsis CRY1. Proc Natl Acad Sci U S A. 2015;112:9135-40 pubmed publisher
    ..We tested this hypothesis by analyzing mutations of Arabidopsis cryptochrome 1 (CRY1) altered in each of the three Trp-triad tryptophan residues (W324, W377, and W400)...
  23. Ong W, Okubo Kurihara E, Kurihara Y, Shimada S, Makita Y, Kawashima M, et al. Chemical-Induced Inhibition of Blue Light-Mediated Seedling Development Caused by Disruption of Upstream Signal Transduction Involving Cryptochromes in Arabidopsis thaliana. Plant Cell Physiol. 2017;58:95-105 pubmed publisher
    ..We demonstrated that 3B7N directly binds to CRY1 protein using an in vitro binding assay...
  24. Ozgur S, Sancar A. Analysis of autophosphorylating kinase activities of Arabidopsis and human cryptochromes. Biochemistry. 2006;45:13369-74 pubmed
    ..Arabidopsis thaliana and humans possess two cryptochromes. Recently, it was found that Arabidopsis cryptochrome 1 (AtCry1) binds ATP and exhibits autokinase activity that is simulated by blue light...
  25. Danon A, Coll N, Apel K. Cryptochrome-1-dependent execution of programmed cell death induced by singlet oxygen in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2006;103:17036-41 pubmed
    ..The singlet oxygen-mediated and cryptochrome-dependent cell death response differs in several ways from PCD triggered by hydrogen peroxide/superoxide. ..
  26. Whippo C, Hangarter R. Second positive phototropism results from coordinated co-action of the phototropins and cryptochromes. Plant Physiol. 2003;132:1499-507 pubmed
    ..Based on our results, we hypothesize that phototropins and cryptochromes regulate phototropism by coordinating the balance between stimulation and inhibition of growth of the hypocotyl depending on the fluence rate of blue light. ..
  27. Pedmale U, Huang S, Zander M, Cole B, Hetzel J, Ljung K, et al. Cryptochromes Interact Directly with PIFs to Control Plant Growth in Limiting Blue Light. Cell. 2016;164:233-245 pubmed publisher
    ..For growth under a canopy, where blue light is diminished, CRY1 and CRY2 perceive this change and respond by directly contacting two bHLH transcription factors, PIF4 and PIF5...
  28. Lian H, He S, Zhang Y, Zhu D, Zhang J, Jia K, et al. Blue-light-dependent interaction of cryptochrome 1 with SPA1 defines a dynamic signaling mechanism. Genes Dev. 2011;25:1023-8 pubmed publisher
    ..Here, we report that CRY1 interacts physically with SPA1 in a blue-light-dependent manner...
  29. Wu L, Yang H. CRYPTOCHROME 1 is implicated in promoting R protein-mediated plant resistance to Pseudomonas syringae in Arabidopsis. Mol Plant. 2010;3:539-48 pubmed publisher
    ..We report here that the Arabidopsis blue light photoreceptor CRY1 positively regulates inducible resistance to Pseudomonas syringae under continuous light conditions...
  30. Partch C, Clarkson M, Ozgur S, Lee A, Sancar A. Role of structural plasticity in signal transduction by the cryptochrome blue-light photoreceptor. Biochemistry. 2005;44:3795-805 pubmed
    ..Importantly, we demonstrate a light-dependent conformational change in the C-terminal domain of Arabidopsis Cry1. Collectively, these findings provide the first biochemical evidence for the proposed conformational rearrangement ..
  31. Vandenbussche F, Habricot Y, Condiff A, Maldiney R, Van Der Straeten D, Ahmad M. HY5 is a point of convergence between cryptochrome and cytokinin signalling pathways in Arabidopsis thaliana. Plant J. 2007;49:428-41 pubmed
    ..of anthocyanin accumulation occurs only in light, and interacts with the signalling pathway downstream of cryptochrome 1 (CRY1) at the level of transcript accumulation of anthocyanin biosynthetic genes...
  32. Shaikhali J, de Dios Barajas López J, Otvös K, Kremnev D, Garcia A, Srivastava V, et al. The CRYPTOCHROME1-dependent response to excess light is mediated through the transcriptional activators ZINC FINGER PROTEIN EXPRESSED IN INFLORESCENCE MERISTEM LIKE1 and ZML2 in Arabidopsis. Plant Cell. 2012;24:3009-25 pubmed publisher
    ..The photoreceptor Cryptochrome 1 (cry1) is essential to the induction of genes encoding photoprotective components in Arabidopsis thaliana...
  33. Jia K, Luo Q, He S, Lu X, Yang H. Strigolactone-regulated hypocotyl elongation is dependent on cryptochrome and phytochrome signaling pathways in Arabidopsis. Mol Plant. 2014;7:528-40 pubmed publisher
    ..The photoreceptor mutants cry1 cry2, phyA, and phyB are hyposensitive to strigolactone analog GR24 under the respective monochromatic light ..
  34. Holtkotte X, Ponnu J, Ahmad M, Hoecker U. The blue light-induced interaction of cryptochrome 1 with COP1 requires SPA proteins during Arabidopsis light signaling. PLoS Genet. 2017;13:e1007044 pubmed publisher
    ..Blue light is sensed by the Arabidopsis photoreceptors CRY1 and CRY2 which subsequently initiate light signal transduction by repressing the COP1/SPA E3 ubiquitin ligase...
  35. Liu Y, Liu Q, Yan Q, Shi L, Fang Y. Nucleolus-tethering system (NoTS) reveals that assembly of photobodies follows a self-organization model. Mol Biol Cell. 2014;25:1366-73 pubmed publisher
  36. Ma D, Li X, Guo Y, Chu J, Fang S, Yan C, et al. Cryptochrome 1 interacts with PIF4 to regulate high temperature-mediated hypocotyl elongation in response to blue light. Proc Natl Acad Sci U S A. 2016;113:224-9 pubmed publisher
    b>Cryptochrome 1 (CRY1) is a blue light receptor that mediates primarily blue-light inhibition of hypocotyl elongation. Very little is known of the mechanisms by which CRY1 affects growth...
  37. El Esawi M, Glascoe A, ENGLE D, Ritz T, Link J, Ahmad M. Cellular metabolites modulate in vivo signaling of Arabidopsis cryptochrome-1. Plant Signal Behav. 2015;10:e1063758 pubmed publisher
    ..In the present work we extend these observations to Arabidopsis cryptochrome 1 and demonstrate that Trp triad substitution mutants at W400F and W324F positions which are not photoreduced in ..
  38. Exner V, Alexandre C, Rosenfeldt G, Alfarano P, Nater M, Caflisch A, et al. A gain-of-function mutation of Arabidopsis cryptochrome1 promotes flowering. Plant Physiol. 2010;154:1633-45 pubmed publisher
    ..Here, we describe the cry1-L407F allele of Arabidopsis (Arabidopsis thaliana), which encodes a hypersensitive cryptochrome1 (cry1) protein...
  39. Zhang X, Wu Y, Tobias J, Brunk B, Deitzer G, Liu D. HFR1 is crucial for transcriptome regulation in the cryptochrome 1-mediated early response to blue light in Arabidopsis thaliana. PLoS ONE. 2008;3:e3563 pubmed publisher
    ..However, the gene targets that are regulated by HFR1 in cryptochrome 1 (cry1)-mediated blue light signaling have not been globally addressed...
  40. Maeda K, Robinson A, Henbest K, Hogben H, Biskup T, Ahmad M, et al. Magnetically sensitive light-induced reactions in cryptochrome are consistent with its proposed role as a magnetoreceptor. Proc Natl Acad Sci U S A. 2012;109:4774-9 pubmed publisher
    ..We argue that cryptochrome is fit for purpose as a chemical magnetoreceptor. ..
  41. Yang Y, Zuo Z, Zhao X, Li X, Klejnot J, Li Y, et al. Blue-light-independent activity of Arabidopsis cryptochromes in the regulation of steady-state levels of protein and mRNA expression. Mol Plant. 2008;1:167-77 pubmed publisher
    ..These results support a hypothesis that, in addition to their blue-light-specific functions, cryptochromes also play roles in the control of gene expression mediated by the red/far-red-light receptor phytochromes. ..
  42. Herbel V, Orth C, Wenzel R, Ahmad M, Bittl R, Batschauer A. Lifetimes of Arabidopsis cryptochrome signaling states in vivo. Plant J. 2013;74:583-92 pubmed publisher
    ..on the loss of degradation of cry2 after prolonged dark incubation and loss of reversibility of photoactivated cry1 by a pulse of green light, we estimate the in vivo half-lives of the signaling states of cry1 and cry2 to be in the ..
  43. Liu B, Zuo Z, Liu H, Liu X, Lin C. Arabidopsis cryptochrome 1 interacts with SPA1 to suppress COP1 activity in response to blue light. Genes Dev. 2011;25:1029-34 pubmed publisher
    ..We report here that Arabidopsis blue-light receptor cryptochrome 1 (CRY1) undergoes blue-light-dependent interaction with the COP1-interacting protein SPA1 (SUPPRESSOR OF ..
  44. Gould P, Ugarte N, Domijan M, Costa M, Foreman J, Macgregor D, et al. Network balance via CRY signalling controls the Arabidopsis circadian clock over ambient temperatures. Mol Syst Biol. 2013;9:650 pubmed publisher
    ..Our analysis provides a systems-level understanding of period control in the plant circadian oscillator. ..
  45. Yuan S, Zhang Z, Zheng C, Zhao Z, Wang Y, Feng L, et al. Arabidopsis cryptochrome 1 functions in nitrogen regulation of flowering. Proc Natl Acad Sci U S A. 2016;113:7661-6 pubmed publisher
    ..time control in Arabidopsis thaliana, namely ferredoxin-NADP(+)-oxidoreductase and the blue-light receptor cryptochrome 1 (CRY1)...
  46. Kondoh M, Shiraishi C, Müller P, Ahmad M, Hitomi K, Getzoff E, et al. Light-induced conformational changes in full-length Arabidopsis thaliana cryptochrome. J Mol Biol. 2011;413:128-37 pubmed publisher
    ..method to detect conformational changes induced by blue-light excitation of full-length Arabidopsis thaliana cryptochrome 1 (AtCRY1)...
  47. Wu G, Spalding E. Separate functions for nuclear and cytoplasmic cryptochrome 1 during photomorphogenesis of Arabidopsis seedlings. Proc Natl Acad Sci U S A. 2007;104:18813-8 pubmed
    ..The cryptochrome 1 (cry1) protein of Arabidopsis is present in the nucleus and cytoplasm of cells, but how the functions of one ..
  48. Fox A, Soto G, Jones A, Casal J, Muschietti J, Mazzella M. cry1 and GPA1 signaling genetically interact in hook opening and anthocyanin synthesis in Arabidopsis. Plant Mol Biol. 2012;80:315-24 pubmed publisher
    While studying blue light-independent effects of cryptochrome 1 (cry1) photoreceptor, we observed premature opening of the hook in cry1 mutants grown in complete darkness, a phenotype that resembles the one described for the ..
  49. Ahmad M, Lin C, Cashmore A. Mutations throughout an Arabidopsis blue-light photoreceptor impair blue-light-responsive anthocyanin accumulation and inhibition of hypocotyl elongation. Plant J. 1995;8:653-8 pubmed
    ..of novel mutations within the Arabidopsis thaliana HY4 gene, which has previously been shown to encode a protein (CRY1) with characteristics of a blue-light photoreceptor...
  50. Cailliez F, Müller P, Gallois M, De La Lande A. ATP binding and aspartate protonation enhance photoinduced electron transfer in plant cryptochrome. J Am Chem Soc. 2014;136:12974-86 pubmed publisher
    ..e., ATP binding and the protonation state of D396 determine the preferred pathway of ISO* relaxation. ..
  51. Sang Y, Li Q, Rubio V, Zhang Y, Mao J, Deng X, et al. N-terminal domain-mediated homodimerization is required for photoreceptor activity of Arabidopsis CRYPTOCHROME 1. Plant Cell. 2005;17:1569-84 pubmed
    ..Here, we report the essential role of the Arabidopsis CRY1 N-terminal domain (CNT1) in the light activation of CRY1 photoreceptor activity...
  52. Chen X, Lin W, Wang Y, Luan S, Xue H. An inositol polyphosphate 5-phosphatase functions in PHOTOTROPIN1 signaling in Arabidopis by altering cytosolic Ca2+. Plant Cell. 2008;20:353-66 pubmed publisher
  53. He Z, Zhao X, Kong F, Zuo Z, Liu X. TCP2 positively regulates HY5/HYH and photomorphogenesis in Arabidopsis. J Exp Bot. 2016;67:775-85 pubmed publisher
    ..a protein, TEOSINTE-LIKE1, CYCLOIDEA, and PROLIFERATING CELL FACTOR 2 (TCP2), which interacts with the cryptochrome 1 (CRY1) protein in yeast and plant cells via the N-terminal domains of both proteins...
  54. Liscum E, Hangarter R. Arabidopsis Mutants Lacking Blue Light-Dependent Inhibition of Hypocotyl Elongation. Plant Cell. 1991;3:685-694 pubmed
    ..Complementation analysis indicated that recessive nuclear mutations at three genetic loci, designated blu1, blu2, and blu3, can result in the blu mutant phenotype and that these mutants are genetically distinct from other ..
  55. Wang Y, Maruhnich S, Mageroy M, Justice J, Folta K. Phototropin 1 and cryptochrome action in response to green light in combination with other wavelengths. Planta. 2013;237:225-37 pubmed publisher
    ..These findings demonstrate how enriched green environments may adjust RL and BL photomorphogenic responses through both the crys and phot1 receptors, and define a new role for phot1 in stem growth promotion. ..
  56. Trupkin S, Mora Garcia S, Casal J. The cyclophilin ROC1 links phytochrome and cryptochrome to brassinosteroid sensitivity. Plant J. 2012;71:712-23 pubmed publisher
    ..1 (ROC1/AtCYP18-3) gene, and partial loss-of function roc1 alleles, has defects in phytochrome A (phyA)-, cryptochrome 1 (cry1)- and phytochrome B (phyB)-mediated de-etiolation, including long hypocotyls under blue or far-red light...
  57. Consentino L, Lambert S, Martino C, Jourdan N, Bouchet P, Witczak J, et al. Blue-light dependent reactive oxygen species formation by Arabidopsis cryptochrome may define a novel evolutionarily conserved signaling mechanism. New Phytol. 2015;206:1450-62 pubmed publisher
    ..Recently, it has been shown that Arabidopsis cry1 activation by blue light also results in direct enzymatic conversion of molecular oxygen (O2 ) to reactive oxygen ..
  58. Ruckle M, DeMarco S, Larkin R. Plastid signals remodel light signaling networks and are essential for efficient chloroplast biogenesis in Arabidopsis. Plant Cell. 2007;19:3944-60 pubmed
    ..Here, we report the isolation of new cryptochrome1 (cry1) alleles from a screen for Arabidopsis thaliana genomes uncoupled mutants, which have defects in plastid-to-nucleus ..
  59. Lopez Juez E, Dillon E, Magyar Z, Khan S, Hazeldine S, de Jager S, et al. Distinct light-initiated gene expression and cell cycle programs in the shoot apex and cotyledons of Arabidopsis. Plant Cell. 2008;20:947-68 pubmed publisher
    ..These data provide the basis for reconstruction of the regulatory networks for light-regulated meristem, leaf, and cotyledon development. ..
  60. Ruckle M, Larkin R. Plastid signals that affect photomorphogenesis in Arabidopsis thaliana are dependent on GENOMES UNCOUPLED 1 and cryptochrome 1. New Phytol. 2009;182:367-79 pubmed publisher
    ..Photomorphogenesis was monitored in genomes uncoupled 1 (gun1), cryptochrome 1 (cry1), and long hypocotyl 5 (hy5), which have defects in light and plastid signaling, by growing Arabidopsis ..
  61. Parks B, Cho M, Spalding E. Two genetically separable phases of growth inhibition induced by blue light in Arabidopsis seedlings. Plant Physiol. 1998;118:609-15 pubmed
    ..depolarization that results from the activation of anion channels by BL was only 30% of the wild-type magnitude in hy4, a mutant lacking the HY4 BL receptor...
  62. Xu C, Li Y, Yu Y, Zhang Y, Wei S. Suppression of Arabidopsis flowering by near-null magnetic field is affected by light. Bioelectromagnetics. 2015;36:476-9 pubmed publisher
    ..However, flowering time of CRY1/CRY2 mutants did not show any difference between plants grown in near-null magnetic field and in local geomagnetic ..
  63. Müller P, Ahmad M. Light-activated cryptochrome reacts with molecular oxygen to form a flavin-superoxide radical pair consistent with magnetoreception. J Biol Chem. 2011;286:21033-40 pubmed publisher
    ..for the reverse reaction, namely dark reoxidation of protein-bound flavin in Arabidopsis thaliana cryptochrome (AtCRY1) by molecular oxygen that involves formation of a spin-correlated FADH(•)-superoxide radical pair...
  64. Xu X, Hotta C, Dodd A, Love J, Sharrock R, Lee Y, et al. Distinct light and clock modulation of cytosolic free Ca2+ oscillations and rhythmic CHLOROPHYLL A/B BINDING PROTEIN2 promoter activity in Arabidopsis. Plant Cell. 2007;19:3474-90 pubmed
    ..Blue light signaling occurs through the redundant action of CRYPTOCHROME1 (CRY1) and CRY2...
  65. He S, Wang W, Zhang J, Xu F, Lian H, Li L, et al. The CNT1 Domain of Arabidopsis CRY1 Alone Is Sufficient to Mediate Blue Light Inhibition of Hypocotyl Elongation. Mol Plant. 2015;8:822-5 pubmed publisher
  66. Zeng J, Wang Q, Lin J, Deng K, Zhao X, Tang D, et al. Arabidopsis cryptochrome-1 restrains lateral roots growth by inhibiting auxin transport. J Plant Physiol. 2010;167:670-3 pubmed publisher
    ..In this study, cryptochrome mutants of Arabidopsis were examined to assess the role of cryptchrome-1 (CRY1) in lateral roots growth...
  67. Keller M, Jaillais Y, Pedmale U, Moreno J, Chory J, Ballaré C. Cryptochrome 1 and phytochrome B control shade-avoidance responses in Arabidopsis via partially independent hormonal cascades. Plant J. 2011;67:195-207 pubmed publisher
    ..These responses to blue light attenuation required the UV-A/blue light photoreceptor cry1. Moreover, they were mediated through mechanisms that showed only limited overlap with the pathways recruited by ..