CGL1

Summary

Gene Symbol: CGL1
Description: alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
Alias: CGL, COMPLEX GLYCAN LESS, COMPLEX GLYCAN LESS 1, F20D10.360, F20D10_360, GNTI, N-ACETYLGLUCOSAMINYLTRANSFERASE I, alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
Species: thale cress

Top Publications

  1. von Schaewen A, Sturm A, O NEILL J, Chrispeels M. Isolation of a mutant Arabidopsis plant that lacks N-acetyl glucosaminyl transferase I and is unable to synthesize Golgi-modified complex N-linked glycans. Plant Physiol. 1993;102:1109-18 pubmed
    ..thaliana with a transgenic strain that expresses the glycoprotein phytohemagglutinin, we obtained a unique strain that synthesizes phytohemagglutinin with two high-mannose glycans, instead of one high-mannose and one complex glycan. ..
  2. Strasser R, Stadlmann J, Svoboda B, Altmann F, Glössl J, Mach L. Molecular basis of N-acetylglucosaminyltransferase I deficiency in Arabidopsis thaliana plants lacking complex N-glycans. Biochem J. 2005;387:385-91 pubmed
    b>GnTI (N-acetylglucosaminyltransferase I) is a Golgi-resident enzyme essential for the processing of high-mannose to hybrid and complex N-glycans...
  3. Kang J, Frank J, Kang C, Kajiura H, Vikram M, Ueda A, et al. Salt tolerance of Arabidopsis thaliana requires maturation of N-glycosylated proteins in the Golgi apparatus. Proc Natl Acad Sci U S A. 2008;105:5933-8 pubmed publisher
    ..Herein, we provide evidence that mutants defective in N-glycan maturation, such as complex glycan 1 (cgl1), are more salt-sensitive than wild type...
  4. Frank J, Kaulfürst Soboll H, Rips S, Koiwa H, von Schaewen A. Comparative analyses of Arabidopsis complex glycan1 mutants and genetic interaction with staurosporin and temperature sensitive3a. Plant Physiol. 2008;148:1354-67 pubmed publisher
    We compare three Arabidopsis (Arabidopsis thaliana) complex glycan1 (cgl1) alleles and report on genetic interaction with staurosporin and temperature sensitive3a (stt3a)...
  5. Bakker H, Lommen A, Jordi W, Stiekema W, Bosch D. An Arabidopsis thaliana cDNA complements the N-acetylglucosaminyltransferase I deficiency of CHO Lec1 cells. Biochem Biophys Res Commun. 1999;261:829-32 pubmed
    ..It has already been shown that a human GlcNAcT-I can complement an A. thaliana mutant (cgl-1)...
  6. Schoberer J, Liebminger E, Botchway S, Strasser R, Hawes C. Time-resolved fluorescence imaging reveals differential interactions of N-glycan processing enzymes across the Golgi stack in planta. Plant Physiol. 2013;161:1737-54 pubmed publisher
  7. Henquet M, Heinhuis B, Borst J, Eigenhuijsen J, Schreuder M, Bosch D, et al. Differential effects of human and plant N-acetylglucosaminyltransferase I (GnTI) in plants. Transgenic Res. 2010;19:535-47 pubmed publisher
    ..first step in complex type N-glycan formation on glycoproteins is catalyzed by N-acetylglucosaminyltransferase I (GnTI)...