CESA6

Summary

Gene Symbol: CESA6
Description: cellulose synthase 6
Alias: E112, ISOXABEN RESISTANT 2, IXR2, MVP7.7, MVP7_7, PRC1, PROCUSTE 1, cellulose synthase 6, cellulose synthase 6
Species: thale cress

Top Publications

  1. Taylor N, Scheible W, Cutler S, Somerville C, Turner S. The irregular xylem3 locus of Arabidopsis encodes a cellulose synthase required for secondary cell wall synthesis. Plant Cell. 1999;11:769-80 pubmed
    ..IRX3 and RSW1 fall into a distinct subgroup (Csa) of Arabidopsis genes showing homology to bacterial cellulose synthases. ..
  2. Desprez T, Vernhettes S, Fagard M, Refregier G, Desnos T, Aletti E, et al. Resistance against herbicide isoxaben and cellulose deficiency caused by distinct mutations in same cellulose synthase isoform CESA6. Plant Physiol. 2002;128:482-90 pubmed
    ..Here, we report on the cloning of IXR2, and show that it encodes another cellulose synthase isoform, CESA6. ixr2-1 carries a mutation substituting an amino acid close to the C terminus of CESA6 that is highly conserved ..
  3. Paredez A, Somerville C, Ehrhardt D. Visualization of cellulose synthase demonstrates functional association with microtubules. Science. 2006;312:1491-5 pubmed
    ..Inhibition of microtubule polymerization changed the fine-scale distribution and pattern of moving CESA complexes in the membrane, indicating a relatively direct mechanism for guidance of cellulose deposition by the cytoskeleton. ..
  4. Turner S, Somerville C. Collapsed xylem phenotype of Arabidopsis identifies mutants deficient in cellulose deposition in the secondary cell wall. Plant Cell. 1997;9:689-701 pubmed
    ..The mutations should be useful in facilitating the identification of factors that control the synthesis and deposition of cellulose and other cell wall components. ..
  5. Desprez T, Juraniec M, Crowell E, Jouy H, Pochylova Z, Parcy F, et al. Organization of cellulose synthase complexes involved in primary cell wall synthesis in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2007;104:15572-7 pubmed
    ..In this study, we show that CESA3 and CESA6 fused to GFP are expressed in the same cells and at the same time in the hypocotyl of etiolated seedlings and ..
  6. Carroll A, Mansoori N, Li S, Lei L, Vernhettes S, Visser R, et al. Complexes with mixed primary and secondary cellulose synthases are functional in Arabidopsis plants. Plant Physiol. 2012;160:726-37 pubmed publisher
    ..and biomolecular fluorescence systems were used to assess the interactions between three primary (CESA1, CESA3, CESA6), and three secondary (CESA4, CESA7, CESA8) Arabidopsis (Arabidopsis thaliana) CESAs...
  7. Paredez A, Persson S, Ehrhardt D, Somerville C. Genetic evidence that cellulose synthase activity influences microtubule cortical array organization. Plant Physiol. 2008;147:1723-34 pubmed publisher
  8. Li S, Lei L, Somerville C, Gu Y. Cellulose synthase interactive protein 1 (CSI1) links microtubules and cellulose synthase complexes. Proc Natl Acad Sci U S A. 2012;109:185-90 pubmed publisher
    ..CSI1 directly binds to microtubules as demonstrated by in vitro microtubule-binding assay. ..
  9. Endler A, Schneider R, Kesten C, Lampugnani E, Persson S. The cellulose synthase companion proteins act non-redundantly with CELLULOSE SYNTHASE INTERACTING1/POM2 and CELLULOSE SYNTHASE 6. Plant Signal Behav. 2016;11:e1135281 pubmed publisher
    ..These data indicate that the CC proteins have a broad role in aiding cellulose synthesis during environmental changes and when core complex components are non-functional. ..

More Information

Publications22

  1. Lei L, Li S, Gu Y. Cellulose synthase interactive protein 1 (CSI1) mediates the intimate relationship between cellulose microfibrils and cortical microtubules. Plant Signal Behav. 2012;7:714-8 pubmed publisher
    ..In addition to a role in serving as a messenger from microtubule to CSCs, CSI1 labels SmaCCs/MASCs, a compartment that has been proposed to be involved in CESA trafficking and/or delivery to the plasma membrane. ..
  2. Wang J, Elliott J, Williamson R. Features of the primary wall CESA complex in wild type and cellulose-deficient mutants of Arabidopsis thaliana. J Exp Bot. 2008;59:2627-37 pubmed publisher
    ..In prc1-19, with no CESA6, CESAs 1 and 3 were part of a 420 kDa complex in extracts of light-grown seedlings that was absent from extracts ..
  3. Mansoori N, Timmers J, Desprez T, Alvim Kamei C, Kamei C, Dees D, et al. KORRIGAN1 interacts specifically with integral components of the cellulose synthase machinery. PLoS ONE. 2014;9:e112387 pubmed publisher
    ..The KOR1 transmembrane domain has shown to be required for the interaction between KOR1 and the different CESAs, as well as for higher oligomer formation of KOR1. ..
  4. MacKinnon I, Šturcová A, Sugimoto Shirasu K, His I, McCann M, Jarvis M. Cell-wall structure and anisotropy in procuste, a cellulose synthase mutant of Arabidopsis thaliana. Planta. 2006;224:438-48 pubmed
    In dark-grown hypocotyls of the Arabidopsis procuste mutant, a mutation in the CesA6 gene encoding a cellulose synthase reduces cellulose synthesis and severely inhibits elongation growth...
  5. Singh S, Fischer U, Singh M, Grebe M, Marchant A. Insight into the early steps of root hair formation revealed by the procuste1 cellulose synthase mutant of Arabidopsis thaliana. BMC Plant Biol. 2008;8:57 pubmed publisher
    ..The Arabidopsis procuste1 (prc1-1) cellulose synthase mutant was studied in order to investigate the role of the cell wall loosening during the ..
  6. Lei L, Li S, Du J, Bashline L, Gu Y. Cellulose synthase INTERACTIVE3 regulates cellulose biosynthesis in both a microtubule-dependent and microtubule-independent manner in Arabidopsis. Plant Cell. 2013;25:4912-23 pubmed publisher
    ..We propose that CSI3 is an important regulator of plant cellulose biosynthesis and plant anisotropic cell growth that modulates the velocity of CSCs in both a microtubule-dependent and microtubule-independent manner. ..
  7. Slabaugh E, Sethaphong L, Xiao C, Amick J, Anderson C, Haigler C, et al. Computational and genetic evidence that different structural conformations of a non-catalytic region affect the function of plant cellulose synthase. J Exp Bot. 2014;65:6645-53 pubmed publisher
    ..The combination of computational and genetic results provides evidence that the ability of the TMH5-6 region to adopt specific structural conformations is important for CESA function. ..
  8. Zhang S, Sun L, Dong X, Lu S, Tian W, Liu J. Cellulose synthesis genes CESA6 and CSI1 are important for salt stress tolerance in Arabidopsis. J Integr Plant Biol. 2016;58:623-6 pubmed publisher
    ..SHE1 encodes a cellulose synthase CESA6 while SHE2 encodes a cellulose synthase-interactive protein CSI1...
  9. Gu Y, Kaplinsky N, Bringmann M, Cobb A, Carroll A, Sampathkumar A, et al. Identification of a cellulose synthase-associated protein required for cellulose biosynthesis. Proc Natl Acad Sci U S A. 2010;107:12866-71 pubmed publisher
    ..CSI1 is associated with CESA complexes, and csi1 mutants affect the distribution and movement of CESA complexes in the plasma membrane. ..
  10. Zhang Y, Nikolovski N, Sorieul M, Vellosillo T, McFarlane H, Dupree R, et al. Golgi-localized STELLO proteins regulate the assembly and trafficking of cellulose synthase complexes in Arabidopsis. Nat Commun. 2016;7:11656 pubmed publisher
    ..Point mutations in the predicted catalytic domains of the STELLO proteins indicate that they are glycosyltransferases facing the Golgi lumen. Hence, we have uncovered proteins that regulate CSC assembly in the plant Golgi apparatus. ..
  11. Chen I, Lo W, Chuang J, Cheuh C, Fan Y, Lin L, et al. A chemical genetics approach reveals a role of brassinolide and cellulose synthase in hypocotyl elongation of etiolated Arabidopsis seedlings. Plant Sci. 2013;209:46-57 pubmed publisher
    ..A map-based cloning approach revealed that CELLULOSE SYNTHASE6 (CESA6) and DE-ETIOLATED2 (DET2) were mutated in ret8 (cesa6(ret8);eto1-4) and ret41 (det2(ret41);eto1-5), respectively...
  12. Gonneau M, Desprez T, Guillot A, Vernhettes S, Höfte H. Catalytic subunit stoichiometry within the cellulose synthase complex. Plant Physiol. 2014;166:1709-12 pubmed publisher
    ..Based on spectral counting, we show that CESA1, CESA3, and CESA6 are present in a 1:1:1 molecular ratio.
  13. Xu S, Rahman A, Baskin T, Kieber J. Two leucine-rich repeat receptor kinases mediate signaling, linking cell wall biosynthesis and ACC synthase in Arabidopsis. Plant Cell. 2008;20:3065-79 pubmed publisher
    ..Furthermore, the FEI proteins interact directly with ACC synthase. These results suggest that the FEI proteins define a novel signaling pathway that regulates cell wall function, likely via an ACC-mediated signal. ..