Gene Symbol: CESA4
Description: cellulose synthase A4
Alias: IRREGULAR XYLEM 5, IRX5, MRH10.14, MRH10_14, NWS2, cellulose synthase A4, cellulose synthase A4
Species: thale cress
Timmers J, Vernhettes S, Desprez T, Vincken J, Visser R, Trindade L. Interactions between membrane-bound cellulose synthases involved in the synthesis of the secondary cell wall. FEBS Lett. 2009;583:978-82 pubmed publisher
..Results indicated that although all CESA proteins can interact with each other, only CESA4 is able to form homodimers. A model is proposed for the secondary rosette structure...
Pear J, Kawagoe Y, Schreckengost W, Delmer D, Stalker D. Higher plants contain homologs of the bacterial celA genes encoding the catalytic subunit of cellulose synthase. Proc Natl Acad Sci U S A. 1996;93:12637-42 pubmed
..Cotton celA1 and celA2 genes are expressed at high levels during active secondary wall cellulose synthesis in developing cotton fibers. Genomic Southern blot analyses in cotton demonstrate that celA forms a small gene family...
Taylor N, Howells R, Huttly A, Vickers K, Turner S. Interactions among three distinct CesA proteins essential for cellulose synthesis. Proc Natl Acad Sci U S A. 2003;100:1450-5 pubmed
..deficient mutants, three lines were shown to be allelic and define a novel complementation group, irregular xylem5 (irx5). IRX5 was cloned and encodes a member of the CesA family of cellulose synthase catalytic subunits (AtCesA4)...
Carroll A, Mansoori N, Li S, Lei L, Vernhettes S, Visser R, et al
. Complexes with mixed primary and secondary cellulose synthases are functional in Arabidopsis plants. Plant Physiol. 2012;160:726-37 pubmed publisher
..systems were used to assess the interactions between three primary (CESA1, CESA3, CESA6), and three secondary (CESA4, CESA7, CESA8) Arabidopsis (Arabidopsis thaliana) CESAs...
Zhang Y, Nikolovski N, Sorieul M, Vellosillo T, McFarlane H, Dupree R, et al
. Golgi-localized STELLO proteins regulate the assembly and trafficking of cellulose synthase complexes in Arabidopsis. Nat Commun. 2016;7:11656 pubmed publisher
..Point mutations in the predicted catalytic domains of the STELLO proteins indicate that they are glycosyltransferases facing the Golgi lumen. Hence, we have uncovered proteins that regulate CSC assembly in the plant Golgi apparatus. ..
Hernández Blanco C, Feng D, Hu J, Sanchez Vallet A, Deslandes L, Llorente F, et al
. Impairment of cellulose synthases required for Arabidopsis secondary cell wall formation enhances disease resistance. Plant Cell. 2007;19:890-903 pubmed
..In Arabidopsis thaliana, three types of CESA subunits (CESA4/IRREGULAR XYLEM5 [IRX5], CESA7/IRX3, and CESA8/IRX1) are required for secondary cell wall formation...
Betancur L, Singh B, Rapp R, Wendel J, Marks M, Roberts A, et al
. Phylogenetically distinct cellulose synthase genes support secondary wall thickening in arabidopsis shoot trichomes and cotton fiber. J Integr Plant Biol. 2010;52:205-20 pubmed publisher
Atanassov I, Pittman J, Turner S. Elucidating the mechanisms of assembly and subunit interaction of the cellulose synthase complex of Arabidopsis secondary cell walls. J Biol Chem. 2009;284:3833-41 pubmed publisher
..These preparations consisted solely of the three known secondary cell wall CESA proteins CESA4, CESA7, and CESA8. No additional CESA isoforms or other proteins were identified...
Mansoori N, Timmers J, Desprez T, Alvim Kamei C, Kamei C, Dees D, et al
. KORRIGAN1 interacts specifically with integral components of the cellulose synthase machinery. PLoS ONE. 2014;9:e112387 pubmed publisher
..The KOR1 transmembrane domain has shown to be required for the interaction between KOR1 and the different CESAs, as well as for higher oligomer formation of KOR1. ..