CDC5

Summary

Gene Symbol: CDC5
Description: cell division cycle 5
Alias: ARABIDOPSIS THALIANA CELL DIVISION CYCLE 5, ARABIDOPSIS THALIANA MYB DOMAIN CELL DIVISION CYCLE 5, ATCDC5, ATMYBCDC5, F21M12.15, F21M12_15, cell division cycle 5, cell division cycle 5
Species: thale cress

Top Publications

  1. Zhang S, Xie M, Ren G, Yu B. CDC5, a DNA binding protein, positively regulates posttranscriptional processing and/or transcription of primary microRNA transcripts. Proc Natl Acad Sci U S A. 2013;110:17588-93 pubmed publisher
    b>CDC5 is a MYB-related protein that exists in plants, animals, and fungi. In Arabidopsis, CDC5 regulates both growth and immunity through unknown mechanisms...
  2. Palma K, Zhao Q, Cheng Y, Bi D, Monaghan J, Cheng W, et al. Regulation of plant innate immunity by three proteins in a complex conserved across the plant and animal kingdoms. Genes Dev. 2007;21:1484-93 pubmed
    ..model, we identified a discrete protein complex containing at least three members--MOS4 (Modifier Of snc1, 4), AtCDC5, and PRL1 (Pleiotropic Regulatory Locus 1)--that are all essential for plant innate immunity...
  3. Monaghan J, Xu F, Gao M, Zhao Q, Palma K, Long C, et al. Two Prp19-like U-box proteins in the MOS4-associated complex play redundant roles in plant innate immunity. PLoS Pathog. 2009;5:e1000526 pubmed publisher
    ..MOS4 is part of a nuclear complex called the MOS4-Associated Complex (MAC) along with the transcription factor AtCDC5 and the WD-40 protein PRL1...
  4. Xu F, Xu S, Wiermer M, Zhang Y, Li X. The cyclin L homolog MOS12 and the MOS4-associated complex are required for the proper splicing of plant resistance genes. Plant J. 2012;70:916-28 pubmed publisher
    ..Our study highlights the contribution of MOS12 and the MAC in the alternative splicing of R?genes, providing regulatory details on how alternative splicing is used to fine-tune R?gene expression in plant immunity. ..
  5. Lin Z, Yin K, Zhu D, Chen Z, Gu H, Qu L. AtCDC5 regulates the G2 to M transition of the cell cycle and is critical for the function of Arabidopsis shoot apical meristem. Cell Res. 2007;17:815-28 pubmed
    ..Here we report the functional characterization of the CDC5 gene in Arabidopsis thaliana. Arabidopsis CDC5 (AtCDC5) is mainly expressed in tissues with high cell division activity, and is expressed throughout the entire process ..
  6. Deng X, Lu T, Wang L, Gu L, Sun J, Kong X, et al. Recruitment of the NineTeen Complex to the activated spliceosome requires AtPRMT5. Proc Natl Acad Sci U S A. 2016;113:5447-52 pubmed publisher
  7. Monaghan J, Xu F, Xu S, Zhang Y, Li X. Two putative RNA-binding proteins function with unequal genetic redundancy in the MOS4-associated complex. Plant Physiol. 2010;154:1783-93 pubmed publisher
    ..Our results suggest that MAC5A is a component of the MAC that contributes to snc1- mediated autoimmunity. ..
  8. Zhang S, Liu Y, Yu B. PRL1, an RNA-binding protein, positively regulates the accumulation of miRNAs and siRNAs in Arabidopsis. PLoS Genet. 2014;10:e1004841 pubmed publisher
    ..We further reveal the genetic interaction of PRL1 with CDC5, which interacts with PRL1 and regulates transcription and processing of pri-miRNAs...
  9. Lin Z, Yin K, Wang X, Liu M, Chen Z, Gu H, et al. Virus induced gene silencing of AtCDC5 results in accelerated cell death in Arabidopsis leaves. Plant Physiol Biochem. 2007;45:87-94 pubmed
    ..In this study, Arabidopsis thaliana CDC5 (AtCDC5) is found to be nuclear localized, and the C-terminus of this protein is of transcriptional activation activity in ..